Abstract:
:The HIV-infected population is ageing. Issues including polypharmacy and co-morbidities led us to develop a dedicated clinic for HIV-infected individuals over 50. We describe our service evaluation after two years. The over 50 clinic commenced in January 2009. The team comprises a registrar, consultant, nurse practitioner and is supported by a pharmacist and mental health services. Patients undergo a full medication and drug interactions review, neurocognitive assessment, adherence self-assessment and investigations including therapeutic drug monitoring (TDM), coronary artery calcium scores (CACS) and bone mineral density. Over two years of activity, 150 patients attended the service. Median (range) age was 58 (50-88), all were on combined antiretroviral therapy and 38% (57/150) were on ≥3 non-HIV drugs. CACS was high (>90th centile) in 14%. Thirty-eight percent had osteopaenia and 18% had osteoporosis requiring treatment. Thirteen out of 125 men had an increased prostate specific antigen, four were diagnosed with prostate cancer. Drug interaction, TDM and neurocognitive assessments were useful for several patients. Asymptomatic patients over 50 in long-term follow-up had new pathologies detected through targeted screening. The clinic has improved general practitioner (GP) liaison and facilitated closer working relationships with other specialties. Patients have reacted positively to the clinic, particularly as many do not routinely access their GP.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Waters L,Patterson B,Scourfield A,Hughes A,de Silva S,Gazzard B,Barton S,Asboe D,Pozniak A,Boffito Mdoi
10.1258/ijsa.2012.011412subject
Has Abstractpub_date
2012-08-01 00:00:00pages
546-52issue
8eissn
0956-4624issn
1758-1052pii
23/8/546journal_volume
23pub_type
杂志文章abstract::Vulval adhesion is a rare but recognized local complication following genital herpes infection. We believe this is only the second reported case of successful resolution of vulval herpetic adhesion using topical potent corticosteroid as the primary early treatment. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007099
更新日期:2008-01-01 00:00:00
abstract::A cross-sectional study of 360 patients presenting with sexually transmitted diseases (STDs) to a primary care clinic in KwaZulu/Natal, South Africa was done. Prevalence of HIV infection was 42.5%. HIV-infected patients were of similar age to uninfected patients (mean age 25.1 vs 26.1 years), but were less likely to b...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921486
更新日期:1998-12-01 00:00:00
abstract::This study assessed lubricant use during receptive anal intercourse (RAI) among Peruvian men who have sex with men (MSM) and willingness to use a hypothetical rectal microbicide (RM) formulated as a lubricant to prevent HIV infection. Data were collected from 843 Peruvian MSM for the 2008 HIV Sentinel Surveillance usi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010134
更新日期:2010-08-01 00:00:00
abstract::We describe a recent outbreak of syphilis in young heterosexuals in the north west of England. A cluster of 12 cases of syphilis (7 primary and 5 early latent) was identified in Rochdale in heterosexuals aged 20 or under. Nine were women. Five were asymptomatic at presentation. This outbreak occurred in a group not us...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011031
更新日期:2011-09-01 00:00:00
abstract::The transition of clinical trial data to changes in routine clinical practice is often a slow process. We describe a rapid transition of patients from one form of antiviral therapy to a modified and potentially safer version that can occur quickly when there are no financial or organisational restrictions on the presc...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418761260
更新日期:2018-09-01 00:00:00
abstract::Patients who do not attend (DNA) clinic appointments are wasteful of resources and may also pose a potential public health risk through the onward transmission of untreated sexually transmitted infections (STIs). This service evaluation was performed to assess the demographics of DNAs, patient reasons for non-attendan...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009349
更新日期:2010-05-01 00:00:00
abstract::A review of published and unpublished data indicates the prevalence of high-risk behaviours for HIV transmission in segments of the Bangladeshi population. These include casual unprotected sex, heterosexual as well as between males, prior to and after marriage. Intravenous drug use (IVDU) exists though illicit drugs a...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991913862
更新日期:1999-03-01 00:00:00
abstract::Factors affecting the eligibility and acceptability of voluntary counselling and rapid HIV testing (VCT) were examined among pregnant women presenting in labour in Pune, India. Of the 6702 total women appearing at the delivery room from April 2001 to March 2002, 4638 (69%) were admitted for normal delivery. The remain...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462054679250
更新日期:2005-08-01 00:00:00
abstract::The primary aim of the current study was to test the effect of the presentation design of a test alert system on healthcare workers' (HCWs') decision-making regarding blood-borne virus (BBV) testing. The secondary aim was to determine HCWs' acceptance of the system. An online survey used a within-subjects research des...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420906998
更新日期:2020-07-01 00:00:00
abstract::In an audit of HIV post-exposure prophylaxis (PEP) programmes in Blantyre, Malawi, and Liverpool, UK, a striking common deficiency was poor attendance of follow-up visits and of HIV testing to determine efficacy of PEP. Causes of poor follow-up after PEP need to be explored in both settings. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010423
更新日期:2011-12-01 00:00:00
abstract::In vivo antimicrobial resistance has yet to be documented in Chlamydia trachomatis; however, there have been anecdotal reports of persistent infection. The purpose of this case series was to describe a group of patients who have persistent chlamydia infection despite adequate treatment and where re-infection was consi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412472815
更新日期:2013-06-01 00:00:00
abstract::Individuals with substance use disorders (SUDs) are at higher risk of HIV infection, yet recent studies show rates of HIV testing are low among this population. We implemented and evaluated a nurse-initiated HIV oral rapid testing (NRT) strategy at three Veterans Health Administration SUD clinics. Implementation of NR...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2012.012050
更新日期:2012-11-01 00:00:00
abstract::The management of cases of gonorrhoea in the Genitourinary Medicine Department (GUM) of Newcastle upon Tyne in 1999 was audited. The sensitivity of microscopy in diagnosis was 90.4% for male urethral gonorrhoea and 26.6% for female genital gonorrhoea. The sensitivity of laboratory culture was 98.5%. Screening for Chla...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001915057
更新日期:2000-10-01 00:00:00
abstract::Ninety women who were HIV antibody positive attended the genitourinary medicine clinics of East Riverside up to May 1990. Seventy-five of these women (83%) were examined for co-existent sexually transmitted disease (STD) at presentation. The prevalence of STD in these women was compared to the incidence of STD in all ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200312
更新日期:1991-05-01 00:00:00
abstract::During 2001 and 2002 an anonymous outreach-screening programme in Melbourne, Australia, offered testing for gonorrhoea and chlamydia on-site at men-only saunas. Modifications were made to this screening programme to offer a comprehensive testing clinic for sexually transmissible infections (STIs), including HIV. The c...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646205774988163
更新日期:2005-12-01 00:00:00
abstract::There is still a paucity of research on the sociodemographic and other underlying factors associated with HIV transmission among women in India. This study was designed to investigate such factors in sexually experienced Indian women. We used data from the National Family Health Survey 3 (NFHS-3), which tested 52,853 ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010127
更新日期:2011-03-01 00:00:00
abstract::People living with HIV (PLH) in Thailand face tremendous challenges, including HIV disclosure. With the advent of antiretroviral (ARV) therapy in Thailand, the positive benefits of HIV disclosure are becoming more salient. However, there are regional variations in the levels of HIV disclosure in Thailand. We examined ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009008
更新日期:2010-03-01 00:00:00
abstract::The incidence of disseminated Mycobacterium avium complex (MAC) infection in HIV patients has fallen markedly since the introduction of effective antiretroviral therapy (ART). However, current guidelines still recommend primary prophylaxis. We conducted a retrospective cohort study in a university-affiliated hospital ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417713432
更新日期:2017-12-01 00:00:00
abstract::Our objective was to investigate whether Postal Test Kits (PTKs) for Chlamydia trachomatis in Edinburgh offer an alternative to genitourinary (GU) medicine clinic attendance. All PTKs returned in the Edinburgh area over a six-month period from August 2005 were audited. Data on age and previous access to GU medicine se...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207780749718
更新日期:2007-05-01 00:00:00
abstract::The first HIV-positive diagnosis among injecting drug users (IDU) in Glasgow was made in 1985. By the end of 1987 prevalence among IDU receiving voluntary attributable tests was 4.8%. Since 1990, an annual cross-sectional survey of HIV prevalence and risk behaviours among 500 current Glasgow IDU has provided a more re...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249400500205
更新日期:1994-03-01 00:00:00
abstract::The aim of this work was to study the human papillomavirus (HPV) type-distribution in condylomata acuminata (CA) of mainland China and to estimate the potential role of HPV prophylactic vaccines for CA in mainland China. Forty-three studies using polymerase chain reaction to detect HPV were included in this meta-analy...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,meta分析
doi:10.1258/ijsa.2008.008040
更新日期:2008-10-01 00:00:00
abstract::Raltegravir is one of the standard antiretroviral therapy (ART) options in treatment-experienced and -naïve patients. However, efficacy data from clinical practice are scarce. Therefore, the efficacy of raltegravir-containing ART in clinical practice was investigated retrospectively. In all, 295 treatment-naïve and -e...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415610678
更新日期:2016-11-01 00:00:00
abstract::Accelerating antiretroviral therapy (ART) administration, improving retention, and achieving viral suppression in low- and middle-income countries must be prioritized. We evaluated trends and disparities in these milestones in a large Latin American cohort. Adults starting ART (ARTstart) from 2003 to 2014 at Caribbean...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462417714094
更新日期:2018-01-01 00:00:00
abstract::The value of microscopy of a Gram-stained urethral smear in the diagnosis of non-gonococcal urethritis and chlamydial urethral infection was assessed in 153 men attending a department of genitourinary medicine. A mean of more than 4 polymorphs in 5 fields (x1000) was considered to be abnormal. In the diagnosis of uret...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200409
更新日期:1991-07-01 00:00:00
abstract::Squamous cell carcinoma of the penis is an uncommon cancer, though in one study it accounted for 90% of all penile cancers. Its association with balanitis xerotica obliterans (BXO) is a rare though recognized occurrence. We describe a case of a 46-year-old Caucasian male who first presented to our open-access clinic w...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206775455658
更新日期:2006-02-01 00:00:00
abstract::A 26-year-old heterosexual man presented with urethral discharge and penile oedema, two days after having a Reverse Prince Albert penile ring replaced. Clinically, he also had genital warts at the piercing tract openings. Investigations revealed positive chlamydial and gonococcal infection of the urethra. The gonococc...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008021
更新日期:2008-07-01 00:00:00
abstract::The aim of this study was to investigate the prevalence of HIV infection in drug addicts and to address their drug habit, sexual life style and socioeconomic factors. This study was conducted among 505 male drug addicts comprising 250 intravenous drug users (IDUs) and 255 non-IDUs. Enzyme-linked immunosorbent assay wa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/09564620360719813
更新日期:2003-11-01 00:00:00
abstract::Infection by human immunodeficiency virus type 2 (HIV-2) has not previously been described in North or East Africa. We examined over 1200 sera of high-risk individuals from three North/East African countries for antibodies to HIV-2. Results indicated that 17 were repeatedly reactive by ELISA; 4 were confirmed by Weste...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249000100113
更新日期:1990-01-01 00:00:00
abstract::Using data from eligible participants, we evaluated procedures of a multi-step enrollment process for an mHealth, pilot randomized controlled trial aimed to promote regular HIV testing among at-risk, diverse sexual minority men. Completion rates of eligible participants were calculated and characterized for these enro...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462419831854
更新日期:2019-06-01 00:00:00
abstract::The first national audit of the management of Chlamydia trachomatis was undertaken by non-consultant career grade doctors working in genitourinary (GU) medicine clinics in the UK. During the audit period of January--March 2004, 1670 data collection forms were completed (from 830 men and 840 women with chlamydia). In a...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462054308431
更新日期:2005-07-01 00:00:00