[Low-affinity Fcγ receptor IIa gene polymorphism and dengue bleeding disorder].

Abstract:

INTRODUCTION:The pathophysiological changes that determine the severity of dengue are still not well known, therefore it is important to study the probable relationship with the host genetic. METHODS:We analyzed the possible association between the FcγRIIa polymorphism and clinical signs in individuals who suffered dengue infection in 2006, using contingency tables. RESULTS:We found that bleeding was significantly associated to FcγRIIa H/H131 genotype (80%). CONCLUSION:Our results suggest that in clinical dengue infection the bleeding could be associated to FcγRIIa H/H131 genotype.

authors

García G,González D,Sánchez L,Pérez AB,Sierra B,Guzmán MG

doi

10.1016/j.eimc.2012.05.011

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

621-3

issue

10

eissn

0213-005X

issn

1578-1852

pii

S0213-005X(12)00208-X

journal_volume

30

pub_type

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    authors: Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC).,Guna Serrano Mdel R,Orta Mira N,Ovies M,Gimeno Cardona C,Pérez JL

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    doi:

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  • [Fever of intermediate duration].

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  • [Orthopedic device-related infections].

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    doi:

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  • [Fasciola hepatica infestation. Biopathology and new diagnostic and therapeutic aspects].

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    pub_type: 杂志文章

    doi:

    authors: de Górgolas M,Torres R,Verdejo C,Garay J,Robledo A,Ponte MC,Fernández Guerrero ML

    更新日期:1992-11-01 00:00:00