Pancreatic adenocarcinoma presenting with sudden onset bilateral deafness secondary to metastatic leptomeningeal infiltration.

Abstract:

:Deafness is a very common problem in older persons. We present a case of metastatic adenocarcinoma of the pancreas with deafness being the patient's only reason for seeking medical attention. The patient had bilateral vestibulocochlear nerve palsies with associated lower motor neurone facial nerve palsies and a bulbar palsy. Magnetic resonance imaging of his brain was unremarkable. It was only on post-mortem histology that tumour infiltrating the leptomeninges was demonstrated. Leptomeningeal metastases are rarely associated with adenocarcinoma of the pancreas. A review of the literature reveals only two other case reports of mestatic pancreatic carcinoma presenting with deafness but both had demonstrable temporal bone lesions on MRI as opposed to the meninges.

journal_name

Age Ageing

journal_title

Age and ageing

authors

Blows SJ,Morgan R,Dhariwal U,Petts G,Roncaroli F

doi

10.1093/ageing/afs085

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

818-9

issue

6

eissn

0002-0729

issn

1468-2834

pii

afs085

journal_volume

41

pub_type

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