Bone metastases in germ cell tumor patients.

abstract：PURPOSE:The aim of this study was to assess the impact of cyclin D1 overexpression (considered separately or jointly with previously assessed p53 and pRb statuses) on survival in a group of 111 surgically treated non-small cell lung cancer patients (NSCLC). METHODS:Cyclin D1 accumulation was assessed immunohistochemic...

journal_title：Journal of cancer research and clinical oncology

authors： Dworakowska D,Jassem E,Jassem J,Boltze C,Wiedorn KH,Dworakowski R,Skokowski J,Jaśkiewicz K,Czestochowska E

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:How could we transfer knowledge about healing plants from other cultures? We analyzed the results of literature search in two exemplary fields-oral mucositis and polyneuropathy. MATERIALS AND METHODS:In both systematic searches of existing literature, we found 57 studies investigating 68 plants from differen...

journal_title：Journal of cancer research and clinical oncology

authors： Büntzel J,Micke O,Büntzel J

更新日期：2021-02-01 00:00:00

abstract：:Primary CNS lymphomas (PCNSL), until recently representing about 1% of all brain tumors, show dramatically increased incidence both in high-risk groups (immunocompromised, AIDS) and in the general population. They are extranodal diffuse non-Hodgkin's lymphomas, the morphology and classification of which are identical ...

journal_title：Journal of cancer research and clinical oncology

authors： Jellinger KA,Paulus W

更新日期：1992-01-01 00:00:00

abstract：:Modulation of 5-fluorouracil (5-FU) is currently being investigated in advanced colorectal cancer. In an attempt to improve the results obtainable for the association of 5-FU and leucovorin, we decided to add cisplatin to 5-FU and (6S)-leucovorin (S-LV) after disease progression. The hypothesis was that a pharmacologi...

journal_title：Journal of cancer research and clinical oncology

authors： Cassano A,Pozzo C,Corsi DC,Fontana T,Noviello MR,Astone A,Barone C

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:Individuals affected by rheumatoid arthritis (RA) occasionally develop lymphoproliferative disorders (RA-LPD). To study the molecular changes underscoring the RA-LPD, mutations of p53 and Bak gene were analyzed in RA-LPD with (MTX-LPD) or without methotrexate treatment for RA (non-MTX-LPD). METHODS:Histology a...

journal_title：Journal of cancer research and clinical oncology

authors： Xu JX,Hoshida Y,Hongyo T,Sasaki T,Miyazato H,Tomita Y,Aozasa K

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To identify and characterize novel genetic alterations in hepatocellular carcinoma (HCC). METHODS:DNA was extracted from 29 HCC and corresponding normal tissues and amplified with 59 different 10-base arbitrary primers. A 550 bp DNA fragment amplified using primer Q-9 and which was present in 19 of 29 cases (6...

journal_title：Journal of cancer research and clinical oncology

authors： Saelee P,Wongkham S,Bhudhisawasdi V,Sripa B,Chariyalertsak S,Petmitr S

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:The development of brain metastases (BMs) was associated with poor prognosis in melanoma patients. Patients with BMs have a median survival of <6 months. Melanoma is the third most common tumor to metastasize to the brain with a reported incidence of 10-40 %. Our aim was to identify factors predicting develo...

journal_title：Journal of cancer research and clinical oncology

authors： Gumusay O,Coskun U,Akman T,Ekinci AS,Kocar M,Erceleb OB,Yazıcı O,Kaplan MA,Berk V,Cetin B,Taskoylu BY,Yildiz A,Goksel G,Alacacioglu A,Demirci U,Algin E,Uysal M,Oztop I,Oksuzoglu B,Dane F,Gumus M,Buyukberber S

更新日期：2014-01-01 00:00:00

abstract：CONTEXT:Parathyroid carcinoma (PC) is a rare endocrine malignancy with no approved systemic therapies for unresectable locally invasive or distant metastatic disease. Understanding the molecular changes in advanced PC can provide better understanding of this disease and potentially help directing targeted therapy. OBJ...

journal_title：Journal of cancer research and clinical oncology

authors： Kutahyalioglu M,Nguyen HT,Kwatampora L,Clarke C,Silva A,Ibrahim E,Waguespack SG,Cabanillas ME,Jimenez C,Hu MI,Sherman SI,Kopetz S,Broaddus R,Dadu R,Wanland K,Williams M,Zafereo M,Perrier N,Busaidy NL

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:A growing body of evidence has shown the possible relevance of survivin -31G>C (rs9904341) promoter polymorphism to the genetic susceptibility of cancer. Because of the lack of available conclusive data, we performed a meta-analysis of all relevant available studies to derive a more precise estimation of the re...

journal_title：Journal of cancer research and clinical oncology

authors： Qin Q,Zhang C,Zhu H,Yang X,Xu L,Liu J,Lu J,Zhan L,Cheng H,Sun X

更新日期：2014-02-01 00:00:00

abstract：:Genetic predisposition is responsible for 5% 10% of all breast cancer cases. Therefore, the inherited susceptibility to breast cancer has been intensively investigated during the last 10 years. In particular, the identification of the breast cancer susceptibility genes BRCA1 (breast cancer gene 1) and BRCA2 and the cu...

journal_title：Journal of cancer research and clinical oncology

authors： Hofmann W,Schlag PM

更新日期：2000-09-01 00:00:00

abstract：:Ovarian cancer is a leading cause of death among gynecologic malignancies. This disappointing prognosis is closely related to intrinsic or acquired resistance to conventional platinum-based chemotherapy, which can affect a third of patients. As such, investigating relevant molecular targets is crucial in the fight aga...

journal_title：Journal of cancer research and clinical oncology

authors： Gasparri ML,Besharat ZM,Farooqi AA,Khalid S,Taghavi K,Besharat RA,Sabato C,Papadia A,Panici PB,Mueller MD,Ferretti E

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The clinical behaviour and outcome of young patients with gastroesophageal tumours (GET) is surmised to differ from older patients, yet data on the comparison of these two patient subgroups is scarce. This study focuses on the investigation of the clinical characteristics and survival outcome of younger-age ...

journal_title：Journal of cancer research and clinical oncology

authors： Puhr HC,Karner A,Taghizadeh H,Jomrich G,Schoppmann SF,Preusser M,Ilhan-Mutlu A

更新日期：2020-12-01 00:00:00

abstract：AIM:In men with adverse pathology after radical prostatectomy, the most appropriate timing to administer radiotherapy (RT) remains a topic of debate. We analyzed in terms of efficacy, prognostic factors and toxicity the two therapeutic strategies: immediate postoperative radiotherapy (PORT) and salvage radiotherapy (SA...

journal_title：Journal of cancer research and clinical oncology

authors： Detti B,Scoccianti S,Cassani S,Cipressi S,Villari D,Lapini A,Saieva C,Cai T,Pertici M,Giacomelli I,Livi L,Ceroti M,Nicita G,Carini M,Biti G

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:In our previous global gene expression analysis, we identified NIPA-like domain containing 1 (NIPAL1), which encodes a magnesium transporter, as one of the most overexpressed genes in recurrent oral squamous cell carcinoma (OSCC). Although has been NIPAL1 linked with gout pathogenesis, little is known about its...

journal_title：Journal of cancer research and clinical oncology

authors： Sasahira T,Nishiguchi Y,Kurihara-Shimomura M,Nakashima C,Kuniyasu H,Kirita T

更新日期：2018-05-01 00:00:00

abstract：AIMS:With three consecutive tetratricopeptide repeat (TPR) motifs at its C-terminus essential for neuronal migration, and a p23 domain at its N-terminus, DYX1C1 was the first gene proposed to have a role in developmental dyslexia. In this study, we attempted to identify the potential interaction of DYX1C1 and heat shoc...

journal_title：Journal of cancer research and clinical oncology

authors： Chen Y,Zhao M,Wang S,Chen J,Wang Y,Cao Q,Zhou W,Liu J,Xu Z,Tong G,Li J

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Despite of the introduction of novel treatment modalities for multiple myeloma, high-dose chemotherapy with hematopoietic stem-cell rescue is still considered the standard of care for eligible patients <65 years of age. As we have previously reported, stem-cell grafts regularly contain quantities of plasma c...

journal_title：Journal of cancer research and clinical oncology

authors： Kopp HG,Yildirim S,Weisel KC,Kanz L,Vogel W

更新日期：2009-04-01 00:00:00

abstract：:Mice with s.c. grafts of gastric carcinoma MKN45 or osteosarcoma 788T were injected i.v. with recombinant tumour necrosis factor alpha (rTNF alpha) and tumour blood flow rates were determined 4 h later as a fraction of the cardiac output g tissue-1. With MKN45, the tumour blood flow rate was significantly reduced from...

journal_title：Journal of cancer research and clinical oncology

authors： Pimm MV,Gribben SJ,Morris TM

更新日期：1991-01-01 00:00:00

abstract：:Formaldehyde is a reactive chemical which undergoes spontaneous reactions with various cellular constituents. Mutagenicity data may be interpreted on the background of this behavior. Mice are better able to reduce the irritating effect of formaldehyde than rats and to reduce their ventilation rate when formaldehyde ac...

journal_title：Journal of cancer research and clinical oncology

authors： Bolt HM

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:We compared laparoscopic approach with the conventional laparotomy approach for the treatment of patients with endometrial carcinoma in developing country. METHODS:Two hundred and seventy-two patients with endometrial carcinoma were enrolled in a prospective randomized trial and treated with laparoscopic or la...

journal_title：Journal of cancer research and clinical oncology

authors： Lu Q,Liu H,Liu C,Wang S,Li S,Guo S,Lu J,Zhang Z

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:Uterine neoplasms comprise a broad spectrum of lesions, some of which may pose a diagnostic challenge even to experienced pathologists. Recently, genome-wide DNA methylation-based classification of central nervous system tumors has been shown to increase diagnostic precision in clinical practice when combined w...

journal_title：Journal of cancer research and clinical oncology

authors： Kommoss FKF,Stichel D,Schrimpf D,Kriegsmann M,Tessier-Cloutier B,Talhouk A,McAlpine JN,Chang KTE,Sturm D,Pfister SM,Romero-Pérez L,Kirchner T,Grünewald TGP,Buslei R,Sinn HP,Mechtersheimer G,Schirmacher P,Schmidt D,Leh

更新日期：2020-01-01 00:00:00

abstract：:Metabolic activation steps involved in carcinogenesis by several aromatic amines, their N-acetylated derivatives, and dialkylnitrosamines are reviewed. N-Hydroxylation is the first activation step in the carcinogenesis by 2-acetylaminofluorene (AAF), other aromatic amides and amines. The cytochrome P-450 enzyme system...

journal_title：Journal of cancer research and clinical oncology

authors： Lotlikar PD

更新日期：1981-01-01 00:00:00

abstract：:Leukaemic and lymphomatous infiltration of the appendix is rare and even rarer is acute appendicitis as the initial manifestation. From our routine biopsy material we collected four cases of haematological malignancies presenting as acute appendicitis or acute abdomen, caused or accompanied by tumoral infiltration of ...

journal_title：Journal of cancer research and clinical oncology

authors： Müller G,Dargent JL,Duwel V,D'Olne D,Vanvuchelen J,Haot J,Hustin J

更新日期：1997-01-01 00:00:00

abstract：:This paper confirms previous results that hyperglycemia (5 g/l) lasting 250 min, when combined with local hyperthermia (43 degrees C) for the last 100 min, strongly inhibits microcirculation in Yoshida sarcomas and DS-carcinosarcomas. This inhibition occurs independently of heparinization of the animals (700 IU/200 G ...

journal_title：Journal of cancer research and clinical oncology

authors： von Ardenne M,Reitnauer PG

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:The feasibility of radioimmunotherapy (RAIT) combined with 5-fluorouracil (5-FU) was examined in colon cancer xenografts. The mode of interaction of the two treatments was also investigated. METHODS:Mice bearing human colon cancer were treated with a combination of 4.63 MBq (L-RAIT) or 9.25 MBq (H-RAIT) (131)I...

journal_title：Journal of cancer research and clinical oncology

authors： Kinuya S,Yokoyama K,Tega H,Hiramatsu T,Konishi S,Watanabe N,Shuke N,Aburano T,Takayama T,Michigishi T,Tonami N

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:Colorectal cancer (CRC) is one of the major health problems worldwide and is often diagnosed at late stage. There is growing body of evidence in early detection of this disease with novel screening modalities to reduce compliance and increase specificity of available methods. The aim of current review is to giv...

journal_title：Journal of cancer research and clinical oncology

authors： Vatandoost N,Ghanbari J,Mojaver M,Avan A,Ghayour-Mobarhan M,Nedaeinia R,Salehi R

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:Serrated adenomas (SAs), which include a wide spectrum of lesions, can be broadly divided into two subtypes: type I, closely mimicking hyperplastic polyps (HPs), and type II, unequivocal adenomatous tumor. Our preliminary findings showed clinicopathologic differences between them. The present study was conducte...

journal_title：Journal of cancer research and clinical oncology

authors： Mitomi H,Sada M,Kobayashi K,Igarashi M,Mori A,Kanazawa H,Nishiyama Y,Ihara A,Otani Y

更新日期：2003-08-01 00:00:00

abstract：INTRODUCTION:Protein profiles of endoscopically collected pancreatic juice from normal, chronic pancreatitis patients and pancreatic cancer patients were compared to identify diagnostic biomarkers of pancreatic cancer. METHODS:Secretin was injected intravenously and pancreatic juice was collected via selective cannula...

journal_title：Journal of cancer research and clinical oncology

authors： Park JY,Kim SA,Chung JW,Bang S,Park SW,Paik YK,Song SY

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:In recurrent ovarian cancer (ROC), there is a high demand on effective therapies with a mild toxicity profile. Treosulfan is an alkylating agent approved as oral (p.o.) and intravenous (i.v.) formulation for the treatment of recurrent ovarian cancer. Data on safety and efficacy for either formulation are rare...

journal_title：Journal of cancer research and clinical oncology

authors： Sehouli J,Tomè O,Dimitrova D,Camara O,Runnebaum IB,Tessen HW,Rautenberg B,Chekerov R,Muallem MZ,Lux MP,Trarbach T,Gitsch G

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:The study aim was to compare the disease control in two groups of patients affected by liver metastases from CRC treated with microwave ablation (MWA) or stereotactic body radiation therapy (SBRT). METHODS:We extracted data of patients treated between 2009 and 2016. Inclusion criteria were: (1) maximum diamete...

journal_title：Journal of cancer research and clinical oncology

authors： Franzese C,Comito T,Clerici E,Di Brina L,Tomatis S,Navarria P,Reggiori G,Viganò L,Poretti D,Pedicini V,Torzilli G,Solbiati L,Scorsetti M

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:To evaluate prognostic factors in estrogen receptor (ER)-positive, operable breast cancer focusing on the progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2). PATIENTS AND METHODS:A total of 819 patients with ER-positive, operable breast cancer were enrolled. All patients received up...

journal_title：Journal of cancer research and clinical oncology

authors： Moon YW,Park S,Sohn JH,Kang DR,Koo JS,Park HS,Chung HC,Park BW

更新日期：2011-07-01 00:00:00