Abstract:
OBJECTIVES:To investigate the diagnostic accuracy, through quantitative analysis, of contrast-enhanced ultrasound (CEUS), using a microbubble contrast agent, in the differentiation of thyroid nodules. METHODS:This prospective study enrolled 46 patients with solitary, scintigraphically non-functional thyroid nodules. These patients were scheduled for surgery and underwent preoperative CEUS with pulse-inversion harmonic imaging after intravenous microbubble contrast medium administration. Using histology as a standard of reference, time-intensity curves of benign and malignant nodules were compared by means of peak enhancement and wash-out enhancement relative to the baseline intensity using a mixed model ANOVA. ROC analysis was performed to assess the diagnostic accuracy in the differentiation of benign and malignant nodules on CEUS. RESULTS:The complete CEUS data of 42 patients (31/42 [73.8%] benign and 11/42 [26.2%] malignant nodules) revealed a significant difference (P < 0.001) in enhancement between benign and malignant nodules. Furthermore, based on ROC analysis, CEUS demonstrated sensitivity of 76.9%, specificity of 84.8% and accuracy of 82.6%. CONCLUSIONS:Quantitative analysis of CEUS using a microbubble contrast agent allows the differentiation of benign and malignant thyroid nodules and may potentially serve, in addition to grey-scale and Doppler ultrasound, as an adjunctive tool in the assessment of patients with thyroid nodules. KEY POINTS:• Contrast-enhanced ultrasound (CEUS) helps differentiate between benign and malignant thyroid nodules. • Quantitative CEUS analysis yields sensitivity of 76.9% and specificity of 84.8%. • CEUS may be a potentially useful adjunct in assessing thyroid nodules.
journal_name
Eur Radioljournal_title
European radiologyauthors
Nemec U,Nemec SF,Novotny C,Weber M,Czerny C,Krestan CRdoi
10.1007/s00330-012-2385-6subject
Has Abstractpub_date
2012-06-01 00:00:00pages
1357-65issue
6eissn
0938-7994issn
1432-1084journal_volume
22pub_type
杂志文章abstract:OBJECTIVES:To evaluate the diffusion characteristics of inflammatory renal lesions and assess whether apparent diffusion coefficient (ADC) values can distinguish them from renal-cell carcinomas (RCCs). METHODS:Eighty-eight patients underwent multidetector computed tomography (MDCT), magnetic resonance imaging (MRI) an...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2577-0
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:To compare the three-dimensional (3D)-fast spin-echo (FSE)-Cube with a conventional imaging protocol in evaluation of dacryostenosis. METHODS:Thirty-three patients with epiphora underwent examinations using Cube magnetic resonance dacryocystography (MRD) and a conventional protocol, which included 3D fast-r...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3462-9
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVES:To investigate if brain gamma-aminobutyric acid (GABA) levels in patients with relapsing-remitting multiple sclerosis (RRMS) are abnormal compared with healthy controls, and their relationship to cognitive function in RRMS. METHODS:Twenty-eight RRMS patients and twenty-six healthy controls underwent magneti...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5064-9
更新日期:2018-03-01 00:00:00
abstract::Sacral insufficiency fractures develop over a period of time and show time-dependent changes. We report on 15 CT examinations of 5 patients with early-stage insufficiency fractures of the sacrum. In 4 patients only irregular sclerosis without distinct fracture lines was present in 7 of 8 fractures. Of these 4 patients...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/BF00187667
更新日期:1996-01-01 00:00:00
abstract::We retrospectively reviewed surgical biopsy findings of lesions diagnosed as radial scars (RS) at stereotactic core-needle biopsy (SCNB). RS was diagnosed in 52 of 1415 (3.7%) consecutive mammographically detected lesions that underwent 14-gauge automated SCNB. Subsequent surgical biopsy findings were available for 43...
journal_title:European radiology
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doi:10.1007/s00330-006-0196-3
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVES:To validate a visual rating scale of frontal atrophy with quantitative imaging and study its association with clinical status, APOE ε4, CSF biomarkers, and cognition. METHODS:The AddNeuroMed and ADNI cohorts were combined giving a total of 329 healthy controls, 421 mild cognitive impairment patients, and 28...
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doi:10.1007/s00330-015-4101-9
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:To develop a non-invasive MRI method for evaluation of liver fibrosis, with histological analysis as the reference standard. METHODS:The study protocol was approved by the Institutional Review Board for Human Studies of our hospital, and written informed consent was obtained from all subjects. Seventy-nine ...
journal_title:European radiology
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doi:10.1007/s00330-011-2249-5
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:To investigate the hepatobiliary enhancement patterns of gadoxetic acid (Gd-EOB-DTPA) MRI and the temporal evolution of focal nodular hyperplasia (FNH)-like lesions in pediatric cancer survivors. METHODS:We retrospectively included pediatric cancer survivors who had new liver lesions detected during surveil...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07157-1
更新日期:2021-01-01 00:00:00
abstract::Although the predominant form of tuberculosis is pulmonary disease, an increasing number of cases with extra-pulmonary involvement have been reported. The diagnosis of extra-pulmonary tuberculosis is often difficult because of its protean clinical manifestations and non-specific laboratory findings. Abdominal lymph no...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-1943-3
更新日期:2004-04-01 00:00:00
abstract::The purpose of this study was to use cine-MRI during continuous respiration to measure the respiratory lumenal diameter change in the pharynx and at an upper tracheal level. Fifteen non-smokers and 23 chronic obstructive pulmonary disease (COPD) patients with smoking history (median 50 pack-years) were included. Cine-...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2461-7
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:This study investigated the diagnostic accuracy of the difference in the cross-sectional areas (CSAs) of affected cervical nerve roots (NRs) for diagnosing cervical radiculopathy (CR). METHODS:In total, 102 CR patients and 219 healthy volunteers were examined with ultrasound. The CSA of the cervical NR at ea...
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更新日期:2017-08-01 00:00:00
abstract::Though recent research into the diagnosis and management of hamstring disorders has resulted in early and accurate recognition of injury, hamstring strain remains the most common form of muscle injury in the active population. With prompt recognition of hamstring strain, an appropriate rest and rehabilitation routine ...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-005-0075-3
更新日期:2006-07-01 00:00:00
abstract::The functional magnetic resonance imaging (fMRI) is often performed at the end of a routine MRI examination during which, dependent on the clinical indication, contrast agent has been administered; however, the effects of Gd-DTPA injection on the results of blood oxygenation level dependent (BOLD)-fMRI remain unknown....
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-2147-6
更新日期:2004-01-01 00:00:00
abstract::We report a case of transient bone marrow edema syndrome migrating within two different compartments of the same knee. This unusual pattern of migration of the marrow edema, which has been previously described only in three cases of transient osteoporosis, may raise the suspicion of an aggressive disease. Radiologists...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1584-y
更新日期:2002-12-01 00:00:00
abstract::An orthopedic surgeon had been condemned for different offences to 2 years and 6 months imprisonment by the superior court in Frankfurt/Main. One point of the ruling had been the use of X-rays without medical indication, which the superior court of Frankfurt/Main finally did not assess as bodily harm. The supreme cour...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050748
更新日期:1999-01-01 00:00:00
abstract::Cystic angiomatosis is a rare disorder with a poor prognosis. We describe a case of a 33-year-old woman who presented with longstanding bone pain, hemolytic anemia, and an enlarged spleen. Radiologically, multiple osseous lesions with a mixed pattern of lytic and sclerotic areas were seen within the shoulders, spine, ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1805-4
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVES:To determine the incremental value of non-contrast CT (NCCT) on dual-energy CT (DECT) in symptomatic first metatarsophalangeal (MTP) joints in early gout. METHODS:One hundred and fifteen painful joints were consecutively enrolled and gout was diagnosed based on the 2015 EULAR/ACR criteria and/or arthrocente...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5716-4
更新日期:2019-03-01 00:00:00
abstract::Noonan's syndrome is a rare congenital disorder that may be associated with abnormalities in the lymphatic drainage. In this case of a 21-year-old man CT after bipedal lymphangiography confirmed the diagnosis of intestinal lymphangiectasy causing protein-losing enteropathy in Noonan's syndrome by showing contrast-enha...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000384
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:To investigate image quality of triple-rule-out (TRO) computed tomography (CT) using a 320-row-detector CT system with substantially reduced contrast medium volume at 100 kV. METHODS:Forty-six consecutive patients with noncritical, acute chest pain underwent 320-row-detector CT using a two-step TRO protocol...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2088-4
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVES:The goal of the present study was to classify the most common types of plain radiographs using a neural network and to validate the network's performance on internal and external data. Such a network could help improve various radiological workflows. METHODS:All radiographs from the year 2017 (n = 71,274) a...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07241-6
更新日期:2020-09-28 00:00:00
abstract:OBJECTIVES:To evaluate whether quantitative susceptibility mapping (QSM) can be employed to detect abnormalities within normal-appearing basal ganglia on conventional MRI in patients with neuropsychiatric systemic lupus erythematosus (NPSLE). METHODS:For 33 SLE patients (13 NPSLE and 20 non-NPSLE patients) and 23 age/...
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pub_type: 杂志文章
doi:10.1007/s00330-015-3929-3
更新日期:2016-04-01 00:00:00
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doi:10.1007/s00330-016-4427-y
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVES:To investigate the diagnostic value of intravoxel incoherent motion (IVIM) DWI for placenta accreta by comparing diffusion and perfusion characteristics of placentas with accreta lesions (APs) with those of normal placentas (NPs). METHODS:Twenty-five pregnant women with AP and 24 with NP underwent 3-T magne...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07200-1
更新日期:2021-02-01 00:00:00
abstract::To purpose of this paper is to study the relation between normal lung maturation signal and changes in intensity ratios (SIR) and to determine which magnetic resonance imaging sequence provides the strongest correlation of normal lung SIs with gestational age. 126 normal singleton pregnancies (20-37 weeks) were examin...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0409-9
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:We sought to determine the relation between major adverse cardiac events (MACE) and anatomical criteria assessed by coronary computed tomography angiography (CCTA) in patients with an anomalous coronary artery with an interarterial course (ACAIAC). MATERIAL AND METHODS:We selected CCTA studies of patients with...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3454-9
更新日期:2015-03-01 00:00:00
abstract::The majority of abnormal findings or lesions on T2-weighted fast spin-echo (FSE) magnetic resonance imaging (MRI) are hyperintense due to increased perfusion or fluid content, such as infections, tumours or synovitis. Hypointense lesions on T2-weighted images (both fat-suppressed and non-fat-suppressed) are less commo...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-015-4027-2
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:X-ray iodinated contrast media have been shown to generate contrast in MR images when used with the chemical exchange saturation transfer (CEST) approach. The aim of this study is to compare contrast enhancement (CE) capabilities and perfusion estimates between radiographic molecules and a Gd-based contrast ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4552-7
更新日期:2017-05-01 00:00:00
abstract::The aim of this study was to assess radiomorphologic and clinical features of tracheal rupture due to blunt chest trauma. From 1992 until 1998 the radiomorphologic and clinical key findings of all consecutive tracheal ruptures were retrospectively analyzed. The study included ten patients (7 men and 3 women; mean age ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050080
更新日期:2000-01-01 00:00:00
abstract::The objective of this study was to optimize ankle joint MR imaging in volunteers at 1.5 Tesla (T) and 3.0 T, and to compare these optimized sequences concerning image quality and performance in assessing cartilage, ligament and tendon pathology in fresh human cadaver specimens. Initially our clinical ankle protocol co...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0446-4
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:To investigate the detectability of pulmonary nodules in chest tomosynthesis at reduced radiation dose levels. METHODS:Eighty-six patients were included in the study and were examined with tomosynthesis and computed tomography (CT). Artificial noise was added to simulate that the tomosynthesis images were ac...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3182-1
更新日期:2014-07-01 00:00:00