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Clinical efficacy of a xenogeneic collagen matrix in augmenting keratinized mucosa around implants: a randomized controlled prospective clinical trial.

Abstract：

AIM:The aim of this controlled randomized clinical trial was to evaluate the efficacy of a xenogeneic collagen matrix (CM) to augment the keratinized tissue around implants supporting prosthetic restorations at 6 months when compared with the standard treatment, the connective tissue autograft, CTG). MATERIALS AND METHODS:This randomized longitudinal parallel controlled clinical trial studied 24 patients with at least one location with minimal keratinized tissue (≤1 mm). MAIN OUTCOME MEASURE:The 6-month width of keratinized tissue. As secondary outcomes the esthetic outlook, the maintenance of peri-implant mucosal health and the patient morbidity were assessed pre-operatively and 1, 3, and 6 months post-operatively. RESULTS:At 6 months, Group CTG attained a mean width of keratinized tissue of 2.75 (1.5) mm, while the corresponding figure in Group CM was 2.8 (0.4) mm, the inter-group differences not being statistically significant. The surgical procedure in both groups did not alter significantly the mucosal health in the affected abutments. There was a similar esthetic result and significant increase in the vestibular depth in both groups as a result of the surgery. In the CM group it changed from 2.2 (3.3) to 5.1 (2.5) mm at 6 months. The patients treated with the CM referred less pain, needed less pain medication, and the surgical time was shorter, although these differences were not statistically significant when compared with the CTG group. CONCLUSIONS:These results prove that this new CM was as effective and predictable as the CTG for attaining a band of keratinized tissue.

journal_name

Clin Oral Implants Res

journal_title

Clinical oral implants research

authors

Lorenzo R,García V,Orsini M,Martin C,Sanz M

doi

10.1111/j.1600-0501.2011.02260.x

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

316-24

issue

3

eissn

0905-7161

issn

1600-0501

journal_volume

23

pub_type

杂志文章,随机对照试验

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