Plasma pseudo cholinesterase deficiency leading to seven hour apnoea in a child undergoing adeno-tonsillectomy.

Abstract:

OBJECTIVE:We report a rare, silent, potentially fatal operative complication of seven hour apnoea in a patient undergoing adenotonsillectomy secondary to deficiency of plasma cholinesterase. Awareness of this hereditary disorder is important to otolaryngologist as; it is difficult to diagnose, can be unexpectedly alarming for parents and the surgeon. METHODS:Case report and review of world literature. RESULTS:A four-year male with obstructive sleep apnoea underwent a routine elective adenotonsillectomy; there was no spontaneous recovery of respiration following surgery. He was transferred to the intensive care unit and 7 h later was successfully weaned from the ventilator and extubated. A plasma cholinesterase level of 456 1U/L was discovered much later. CONCLUSION:To our knowledge this is the first case report of pseudo cholinesterase deficiency reported in otolaryngology literature and first in Oman. The patient should receive information about the condition, the associated risks, inheritance and need for testing other family members.

authors

Bhargava D,Sharma J,Al-Abri R

doi

10.1016/j.ijporl.2011.10.010

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

149-51

issue

1

eissn

0165-5876

issn

1872-8464

pii

S0165-5876(11)00528-3

journal_volume

76

pub_type

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