Optimising the dose of oral midazolam sedation for dental procedures in children: a prospective, randomised, and controlled study.

Abstract:

BACKGROUND:Midazolam sedation poses a significant dilemma in paediatric dentistry, which is to find out the optimal dosing with minimal undesirable adverse events. In this study, we aimed to compare the effect of three doses of oral midazolam (0.5, 0.75, and 1 mg/kg) on the sedative state and cooperative behaviour of children during dental treatment. We further compared completion rates, parent satisfaction, and all adverse events. DESIGN:Ninety children aged 3-10 years were randomised to three equal groups. Groups A, B, and C received 0.5, 0.75, and 1 mg/kg of oral midazolam, respectively. Levels of sedation, cooperative behaviour, procedures completion rates, parent satisfaction, and adverse events were prospectively recorded. RESULTS:Sedation scores in B and C were higher (P < 0.001) than in A. Cooperation scores (CS) in B and C were higher (P < 0.001) than in A. Significant increase in completion rates was observed between A and C (P = 0.025). Parent satisfaction was greater in B and C (P < 0.001) compared to A. Adverse events were higher in C (P < 0.05) than in A or B. CONCLUSION:Amount of 0.75 mg/kg oral midazolam appears to be the optimal oral dose in terms of effectiveness, acceptability, and safety for dental treatments in paediatric patients, when administered by an experienced, paediatric anaesthetist.

journal_name

Int J Paediatr Dent

authors

Somri M,Parisinos CA,Kharouba J,Cherni N,Smidt A,Abu Ras Z,Darawshi G,Gaitini LA

doi

10.1111/j.1365-263X.2011.01192.x

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

271-9

issue

4

eissn

0960-7439

issn

1365-263X

journal_volume

22

pub_type

杂志文章,随机对照试验
  • Attitudes of Saudi Arabian mothers towards the digit-sucking habit in children.

    abstract:OBJECTIVE:The purpose of this study was to report on the attitudes of Saudi mothers towards the digit-sucking habit in their children and their attempts to stop this fixation. DESIGN:The research took the form of a cross-sectional study. METHODS:Data was collected from a sample of 50 Saudi mothers whose children curr...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263X.2004.00567.x

    authors: Al-Jobair A,Al-Emran SE

    更新日期:2004-09-01 00:00:00

  • Management of 'double teeth' in children and adolescents.

    abstract:BACKGROUND:Abnormally, large teeth are often referred to as 'double teeth'. These can pose numerous challenges for the clinician. There is no published protocol on the management of double teeth. AIM:To review the published literature and also patients managed at the Eastman Dental Hospital (EDH) and to develop a clin...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-263X.2011.01209.x

    authors: Shah P,Chander JM,Noar J,Ashley PF

    更新日期:2012-11-01 00:00:00

  • Influence of local anaesthesia on the quality of class II glass ionomer restorations.

    abstract:OBJECTIVE:To investigate the influence of local anaesthesia on the quality of class II glass ionomer restorations with discomfort as cofactor. MATERIAL AND METHODS:The study population consisted of 6- to 7-year-old schoolchildren in Paramaribo and its environs. To be included, each child needed to have a proximally si...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-263X.2007.00818.x

    authors: Van de Hoef N,Van Amerongen E

    更新日期:2007-07-01 00:00:00

  • Rhabdomyosarcoma of the mandible in a 6-year-old boy.

    abstract:INTRODUCTION:Rhabdomyosarcoma is an aggressive malignant tumour composed of neoplastic mesenchymal cells that infiltrate surrounding tissue structures, making their precise site of origin unclear. Although rare, this is highly aggressive and the most common soft-tissue neoplasm of the head and neck in children. Regrett...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263X.2006.00732.x

    authors: Davidson LE,Soldani FA,North S

    更新日期:2006-07-01 00:00:00

  • Vitamin D receptor FokI and BglI genetic polymorphisms, dental caries, and gingivitis.

    abstract:BACKGROUND & AIM:To investigate the association between the genetic polymorphisms FokI (rs2228570) and BglI (rs739837) in vitamin D receptor (VDR) with dental caries and gingivitis susceptibility. DESIGN:This study included 353 Brazilian children (8 to 11 years old). Dental caries was assessed using ICDAS (Internation...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/ipd.12631

    authors: Barbosa MCF,Lima DC,Reis CLB,Reis ALM,Rigo D Jr,Segato RAB,Storrer CLM,Küchler EC,de Oliveira DSB

    更新日期:2020-09-01 00:00:00

  • Premature loss of primary anterior teeth and its consequences to primary dental arch and speech pattern: A systematic review and meta-analysis.

    abstract:BACKGROUND:Information about the functional and morphological consequences that occur following the premature loss of anterior teeth is still insufficient. AIM:To evaluate the consequences in children's speech and arch integrity following premature loss of primary anterior teeth compared to those without premature los...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/ipd.12644

    authors: Nadelman P,Bedran N,Magno MB,Masterson D,de Castro ACR,Maia LC

    更新日期:2020-11-01 00:00:00

  • Dental treatment of children referred to general anaesthesia--association with country of origin and medical status.

    abstract:BACKGROUND:A small proportion of children and adolescents need dental treatment with general anaesthesia (DGA). The aim of this retrospective cross-sectional study was to analyse how country of origin and medical status were related to age at treatment, waiting times in the system, and dental treatment provided in gene...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263X.2006.00737.x

    authors: Haubek D,Fuglsang M,Poulsen S,Rølling I

    更新日期:2006-07-01 00:00:00

  • Children's dental health in Europe: caries experience of 5- and 12-year-old children from eight EU countries.

    abstract::Data on the current dental health of 5- and 12-year-old children from eight European countries has been collected by calibrated examiners. In each country a random sample of 200 children in each age group was drawn from urban primary and secondary state schools, a total of 3200 subjects. The children were examined und...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263x.1996.tb00234.x

    authors: Bolin AK,Bolin A,Koch G

    更新日期:1996-09-01 00:00:00

  • A study into dentists' knowledge of the treatment of traumatic injuries to young permanent incisors.

    abstract:OBJECTIVE:The aims of this study were to evaluate dentists' knowledge of the emergency treatment of traumatic injuries to young permanent incisors, and to investigate barriers to treatment. DESIGN:A closed-ended questionnaire was sent to 1023 general dental practitioners (GDPs) and community dental officers (CDOs) in ...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263X.2005.00588.x

    authors: Kostopoulou MN,Duggal MS

    更新日期:2005-01-01 00:00:00

  • Stainless steel crown versus modified open-sandwich restorations for primary molars: a 2-year randomized clinical trial.

    abstract:OBJECTIVE:The aim of this study was to investigate the clinical performance and survival of stainless steel crown (SSC) restoration and modified open-sandwich technique using resin-modified glass ionomer cement. DESIGN:Randomized clinical trial. SETTING:General dental practice. MATERIALS AND METHODS:A total of 87 ch...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-263X.2007.00900.x

    authors: Atieh M

    更新日期:2008-09-01 00:00:00

  • Cross-cultural adaptation and psychometric properties of the Hindi version of Child Perception Questionnaire (CPQ11-14 ) in school children.

    abstract:BACKGROUND:There is a need to validate OHRQoL measures in Hindi to assess the OHRQoL of Indian children. AIM:To develop a Hindi version of the CPQ11-14 and to appraise its validity and reliability for use among North Indian children aged 11-14 years. DESIGN:The cross-culturally adapted Hindi version of CPQ11-14 was a...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/ipd.12693

    authors: Jain V,Agarwal N,Jabin Z,Singh S,Anand A,Jain M

    更新日期:2020-08-06 00:00:00

  • Factors affecting dental fear in French children aged 5-12 years.

    abstract:BACKGROUND:While dental anxiety is often correlated with prior negative dental experience, prevention of dental anxiety should in theory include early exposure to the dental setting. OBJECTIVE:We set out to evaluate factors affecting dental fear in French children. METHODS:Dental fear was evaluated using a visual ana...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263X.2010.01054.x

    authors: Nicolas E,Bessadet M,Collado V,Carrasco P,Rogerleroi V,Hennequin M

    更新日期:2010-09-01 00:00:00

  • Capnocytophaga in the dental plaque of immunocompromised children with cancer.

    abstract:OBJECTIVES:(i) To compare the prevalence and levels of Capnocytophaga, a known systemic pathogen in immunocompromised patients, in the dental plaque of healthy children and children with cancer, and (ii) to determine the susceptibility of strains isolated from cancer patients to a range of antibiotics. PATIENTS AND ME...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263X.2006.00697.x

    authors: Sixou JL,Aubry-Leuliette A,De Medeiros-Battista O,Lejeune S,Jolivet-Gougeon A,Solhi-Pinsard H,Gandemer V,Barbosa-Rogier M,Bonnaure-Mallet M

    更新日期:2006-03-01 00:00:00

  • First dental visit of children-A mixed-method approach.

    abstract:BACKGROUND:First dental visit (FDV), the essence of preventive paediatric dentistry, has a significant impact on the child's oral health. Mixed-method research provides meaningful insight into the multiple facets of FDV. AIM:To evaluate the average age and most common reason for FDV of children in Namakkal district an...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/ipd.12665

    authors: Viswanath S,Asokan S,Pollachi-Ramakrishnan G

    更新日期:2020-05-19 00:00:00

  • Deep caries due to Pre-eruptive intracoronal resorption in a newly erupted primary molar.

    abstract:CASE REPORT:This report describes a rare case of a 19-month-old girl with pre-eruptive intracoronal resorption in the lower left first primary molar which had erupted a few weeks earlier and had deep caries. The treatment is described. CONCLUSION:Dentists who treat children must take into consideration the possibility...

    journal_title:International journal of paediatric dentistry

    pub_type:

    doi:10.1111/ipd.12283

    authors: Schwimmer Y,Zeltser R,Moskovitz M

    更新日期:2017-07-01 00:00:00

  • Aspiration of an avulsed primary incisor. A case report.

    abstract::A 7-year-old girl had injured her maxillary primary incisors in a playground. One of the already-mobile incisors had been avulsed. The child who had a cough and breathing difficulties during sleep was diagnosed as suffering from upper respiratory infection and was treated with antibiotics. A few days later because her...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1046/j.1365-263x.2000.00185.x

    authors: Holan G,Ram D

    更新日期:2000-06-01 00:00:00

  • Resin infiltration of developmentally hypomineralised enamel.

    abstract:BACKGROUND:Molar incisor hypomineralisation (MIH) is a problematic condition with several characteristics for which infiltrant resins could theoretically improve clinical outcomes. AIM:To investigate whether caries infiltrant resin can penetrate MIH-affected enamel. DESIGN:Molar incisor hypomineralisation lesions (n ...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/ipd.12025

    authors: Crombie F,Manton D,Palamara J,Reynolds E

    更新日期:2014-01-01 00:00:00

  • Eruption of a permanent mandibular canine in a 5-year-old boy.

    abstract::The premature eruption of a mature mandibular permanent canine is described in a healthy 5-year-old boy with developmental absence of the primary predecessor. The effects of early loss or missing primary teeth on eruption timing of the permanent successors are discussed. The very early maturation of the permanent cani...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1046/j.1365-263x.2003.00431.x

    authors: Turnbull NR,Lai NN

    更新日期:2003-03-01 00:00:00

  • Variations in expression of oral-facial-digital syndrome (type I): report of two cases.

    abstract::Two case reports are presented, both clearly demonstrating the diagnosis of oral-facial-digital syndrome, type I, but widely different in the expression of the condition. The first patient showed only mild expression of the syndrome. On examination at the age of 4 years there were no obvious extra oral signs, intraora...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263x.2004.00503.x

    authors: Driva T,Franklin D,Crawford PJ

    更新日期:2004-01-01 00:00:00

  • A systematic review of dietary acids and habits on dental erosion in adolescents.

    abstract:BACKGROUND:Dental erosion is the dissolution of dental hard tissues caused by acids of a non-bacterial origin. Dietary acids are considered the predominant and most controllable factor. AIM:To synthesise the literature on the effects of dietary acids and habits on dental erosion in the permanent dentition of 10- to 19...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章,评审

    doi:10.1111/ipd.12643

    authors: Chan AS,Tran TTK,Hsu YH,Liu SYS,Kroon J

    更新日期:2020-11-01 00:00:00

  • Seen but not heard: a systematic review of the place of the child in 21st-century dental research.

    abstract:BACKGROUND:The position of children in society has changed with increasing emphasis on children's rights and child-centred services. This study aimed to describe the extent to which contemporary oral health research has been conducted with or on children. DESIGN:A systematic review of the child dental literature from ...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-263X.2007.00845.x

    authors: Marshman Z,Gibson BJ,Owens J,Rodd HD,Mazey H,Baker SR,Benson PE,Robinson PG

    更新日期:2007-09-01 00:00:00

  • Investigation of the effect of FK506 (tacrolimus) and cyclosporin on gingival overgrowth following paediatric liver transplantation.

    abstract:INTRODUCTION:Gingival overgrowth associated with immunosuppression following liver transplantation is a commonly recognized clinical problem. The aims of this study were to determine the incidence of gingival overgrowth in a group of children post liver transplantation and to compare gingival overgrowth in children rec...

    journal_title:International journal of paediatric dentistry

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-263x.2002.00397.x

    authors: McKaig SJ,Kelly D,Shaw L

    更新日期:2002-11-01 00:00:00

  • Oral status, sense of coherence, religious-spiritual coping, socio-economic characteristics, and quality of life in young patients.

    abstract:BACKGROUND:Several factors can influence the oral health. AIM:To explore the clinical factors, individual characteristics, and environmental factors (religious-spiritual coping-RSC, sense of coherence [SOC], and socio-economic status) related to oral status and impact on oral health-related quality of life (OHRQoL) of...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/ipd.12594

    authors: Soares TRC,Lenzi MM,Leite IM,Muniz Loureiro J,Leão ATT,Pomarico L,Neiva da Silva A,Risso PA,Vettore MV,Maia LC

    更新日期:2020-03-01 00:00:00

  • Reported infant feeding, oral hygiene and dental attendance patterns in children aged 5 years and under referred for extraction of teeth under general anaesthesia.

    abstract::This study was designed to examine reported infant feeding, oral hygiene, and dental attendance practices in children who had established dental disease before attaining school age. Data were collected by structured interview from the mothers of 150 children aged 5 years and under who were referred to a hospital Paedi...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1046/j.1365-263x.1997.00049.x

    authors: Hunter ML,Hood CA,Hunter B,Kingdon A

    更新日期:1997-12-01 00:00:00

  • Tooth agenesis: a report of missing molars in two generations.

    abstract::A recent review has suggested that tooth agenesis is becoming more evident in society, though it is not known whether this observation is related to better detection methods and patient awareness or whether there is a real trend towards an increase in prevalence. In this paper we report developmental absence of perman...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1046/j.1365-263x.2003.00479.x

    authors: Kau CH,Hunter ML,Lewis B,Knox J

    更新日期:2003-09-01 00:00:00

  • Kartagener's syndrome: unusual dental morphology.

    abstract::The present paper describes the dental presentation of a female patient with Kartagener's syndrome. There are no reports in the literature identifying dental anomalies in patients with this condition. The subject presented with the congenital absence of an upper lateral incisor, enamel hypoplasia and aberrant tooth mo...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263X.2005.00629.x

    authors: Merrett SJ,Durning P

    更新日期:2005-05-01 00:00:00

  • Outcome of an oral health outreach programme for preschool children in a low socioeconomic multicultural area.

    abstract:BACKGROUND:Despite a significant reduction in the prevalence of dental caries, childhood tooth decay is still a public health problem in both developed and developing countries. OBJECTIVE:The aim of this study was to evaluate the caries preventive effect of an oral health programme for preschool children living in a l...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263X.2007.00903.x

    authors: Wennhall I,Matsson L,Schröder U,Twetman S

    更新日期:2008-03-01 00:00:00

  • Bond strength and morphology of resin materials applied to the occlusal surface of primary molars.

    abstract:BACKGROUND:Hydrophilic adhesives may be used as pit and fissure sealants (sealants), but there is concern about the ability of self-etching adhesives to bond sealants to enamel. AIM:To study the bond strength (BS) and morphology of adhesive systems used as sealants. DESIGN:OptiBond FL, OptiBond All-in-One, combined O...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1111/j.1365-263X.2011.01213.x

    authors: Lemos LV,Felizardo KR,Myaki SI,Lopes MB,Moura SK

    更新日期:2012-11-01 00:00:00

  • Correction of anterior dental crossbite with composite as an inclined plane.

    abstract:OBJECTIVE:The purpose of this study was to evaluate a passive method to correct anterior crossbite of only one incisor by constructing a composite inclined plane. SAMPLE AND METHOD:A total of 35 children aged 7-11 with a crossbite of only one incisor tooth were selected for this study. An inclined composite block 3-4 ...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1046/j.1365-263x.2001.00256.x

    authors: Sari S,Gokalp H,Aras S

    更新日期:2001-05-01 00:00:00

  • The management of severe dental phobia in an adolescent boy: a case report.

    abstract::Dental fear is a widespread problem that represents one of the major barriers to dental care. This report describes a case study of a 12-year-old boy who presented with dental phobia characterized as 'fear of catastrophe', 'generalized dental fear' and 'fear of specific stimuli'. The referral came from his general den...

    journal_title:International journal of paediatric dentistry

    pub_type: 杂志文章

    doi:10.1046/j.1365-263x.2000.00218.x

    authors: Levitt J,Mcgoldrick P,Evans D

    更新日期:2000-12-01 00:00:00