Abstract：
BACKGROUND:Test Your Memory (TYM) test is a recently described cognitive test instrument designed to be self-administered under medical supervision. The pragmatic role of such self-administered tests in cognitive clinics has not previously been examined. We investigated the diagnostic utility of the TYM as an independent test to differentiate patients with and without dementia at initial clinical diagnostic interview in dedicated memory clinics. METHODS:TYM was administered to consecutive new patient referrals to two memory clinics independent of other tests [Mini-Mental State Examination (MMSE) and the Addenbrooke's Cognitive Examination-Revised] which were used to establish diagnoses according to standard diagnostic criteria (DSM-IV), and results were compared. RESULTS:In a cohort of 224 patients, 35% fulfilling clinical diagnostic criteria for dementia, TYM proved easy to use and acceptable to patients. Downward adjustment of the TYM test cutoff to ≤30/50, compared to ≤42/50 used in the index study, proved necessary to maximise test accuracy and specificity. Using this revised cutoff, TYM showed comparable diagnostic utility (sensitivity 0.73, specificity 0.88, positive predictive value 0.77, negative predictive value 0.86 and area under receiver operating characteristic curve 0.89) to the MMSE and the Addenbrooke's Cognitive Examination-Revised for the differentiation of cases of dementia from non-dementia. CONCLUSIONS:TYM is a useful screening test in the cognitive function clinic setting, with patients who fall below the designated cutoff requiring further investigation to ascertain a cause for their cognitive impairment. Self-administered tests such as TYM may be of particular value in situations where clinician time is limited.
journal_name
Int J Geriatr Psychiatryjournal_title
International journal of geriatric psychiatryauthors
Hancock P,Larner AJdoi
10.1002/gps.2639subject
Has Abstractpub_date
2011-09-01 00:00:00pages
976-80issue
9eissn
0885-6230issn
1099-1166journal_volume
26pub_type
杂志文章abstract：BACKGROUND:Based on the hypothesis that declarative memory and navigation ability depend on hippocampal integrity, and the fact that declarative memory declines early in Alzheimer's disease (AD), the authors suggest that topographical disorientation (TD) will be an early manifestation of AD. SUBJECTS AND METHODS:Patie...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1081
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVES:Insulin resistance is a substantial health issue for American Indians, with type 2 diabetes overrepresented in this population as compared with non-Hispanic whites. Insulin resistance and its related conditions in turn increase risk for dementia and cognitive impairment. The aim of the current study was to d...
journal_title：International journal of geriatric psychiatry
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更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:Exposure to negative life events (NLEs) and neuroticism are associated with dementia. It is unknown whether neuroticism explains or modifies the association of NLEs with dementia in older Black and White Brazilians. METHODS:A total of 1747 decedents 65 years and older White and Black (11% Black and 23% Mixed...
journal_title：International journal of geriatric psychiatry
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journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.539
更新日期：2002-02-01 00:00:00
abstract：OBJECTIVE:This study aimed to: (i) replicate previous findings that women experience more strain and distress than men when caring for dementing spouses; (ii) explore what factors underlie this sex difference. DESIGN:Two closely matched subsamples of spouse carers, husbands and wives respectively, were selected and th...
journal_title：International journal of geriatric psychiatry
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journal_title：International journal of geriatric psychiatry
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journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,多中心研究
doi：10.1002/gps.4781
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journal_title：International journal of geriatric psychiatry
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doi：10.1002/(sici)1099-1166(199906)14:6<494::aid-gps96
更新日期：1999-06-01 00:00:00
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journal_title：International journal of geriatric psychiatry
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doi：10.1002/gps.4047
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journal_title：International journal of geriatric psychiatry
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更新日期：2005-11-01 00:00:00
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journal_title：International journal of geriatric psychiatry
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doi：10.1002/gps.2612
更新日期：2011-08-01 00:00:00
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doi：10.1002/gps.4359
更新日期：2016-05-01 00:00:00
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journal_title：International journal of geriatric psychiatry
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doi：10.1002/gps.5063
更新日期：2019-09-01 00:00:00
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journal_title：International journal of geriatric psychiatry
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1002/gps.1038
更新日期：2004-01-01 00:00:00
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doi：10.1002/gps.4389
更新日期：2016-07-01 00:00:00
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pub_type： 临床试验,杂志文章,多中心研究
doi：10.1002/gps.1486
更新日期：2006-05-01 00:00:00
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journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2416
更新日期：2010-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-12-01 00:00:00
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journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
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journal_title：International journal of geriatric psychiatry
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更新日期：1997-05-01 00:00:00
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journal_title：International journal of geriatric psychiatry
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doi：
更新日期：1997-08-01 00:00:00
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更新日期：2010-02-01 00:00:00
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journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.463
更新日期：2001-10-01 00:00:00
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journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,多中心研究
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更新日期：2003-01-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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更新日期：2018-02-01 00:00:00
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journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
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更新日期：2016-09-01 00:00:00
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journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5074
更新日期：2019-05-01 00:00:00
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journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,评审
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更新日期：2011-06-01 00:00:00
