Abstract：
PURPOSE:The purpose of the current study was to determine whether or not the quadruple test for screening Down syndrome is an effective method to replace direct amniocentesis in pregnant women ≥ 35 years of age. METHODS:This study analyzed the screening performance of the quadruple test according to maternal age at delivery among subjects who had a quadruple screening test at 1 of 4 hospitals during a 5-year period and for whom data on fetal chromosomal abnormalities were available. RESULTS:The study population of 9,435 pregnant women was divided into 3 groups according to maternal age: 6,922 women were < 35 years of age; 2,284 were 35-39 years of age; and 229 women ≥ 40 years of age. The detection and false-positive rates of the quadruple screening test for Down or Edward syndrome in the 3 groups of women were 80 and 6.6%, 200 and 15.8%, and 100 and 35.3%, respectively. CONCLUSIONS:Under conditions in which first trimester screening test is not available, the quadruple screening test is a better choice than direct amniocentesis for pregnancies complicated by advanced maternal age. When providing genetic counseling, we need to explain the accurate detection and false-positive rates of the screening test according to maternal age.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Kwon JY,Park IY,Kwon SM,Kim CJ,Shin JCdoi
10.1007/s00404-011-2052-1subject
Has Abstractpub_date
2012-03-01 00:00:00pages
629-33issue
3eissn
0932-0067issn
1432-0711journal_volume
285pub_type
杂志文章abstract：:In this study, our aim was to compare the effects of metformin and gonadotropin releasing hormone (GnRH) analogues in clinical and hormonal parameters in women with polycystic ovary syndrome (PCOS). There were 50 women with PCOS who were included in our study and they were divided into two groups. In this randomized t...
journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00404-002-0344-1
更新日期：2003-06-01 00:00:00
abstract：PURPOSE:To assess the effects of Kampo, a traditional Japanese adaptation of Chinese herbal medicine, on peri- and postmenopausal women with sleep disturbances. METHODS:Among the records of 1,523 peri- and postmenopausal women who are enrolled in the Health and Nutrition Education Program at the Tokyo Medical and Dent...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1779-4
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Few case reports describing endometriosis in patients with gonadal dysgenesis have been published, but none has reported the presence of adenomyosis in a patient with Turner's syndrome. CASE:A 31-year-old woman with mosaic Turner's Syndrome (45,X/46,XX/47,XXX) was referred to us because of severe iron defic...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-004-0603-4
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:Non-gestational ovarian choriocarcinoma (NGOC) is a rare malignant germ cell tumor. Through literature review and cases collection, we aim to analyze prognostic factors for NGOC and summarize its clinicopathological characteristics to guide the individualized treatment. METHODS:We searched PubMed database, Coc...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-020-05502-9
更新日期：2020-04-01 00:00:00
abstract：INTRODUCTION:In recent years, researchers have postulated a decreasing fertility potential of males and a rising incidence of testicular malignancies. MATERIALS AND METHODS:In this retrospective observational diagnostic multicenter study, 302 patient files of subfertile men whose testes were biopsied for TESE procedur...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-1938-2
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:To determine the prognostic value of the immunohistochemical evaluation of the multidrug resistance-associated protein 2 (MRP2) expression, together with its subcellular localization in primary fallopian tube carcinomas (PFTCs). METHODS:The immunohistochemical analysis was performed using samples originating...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2589-7
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:To present and discuss 28 female cases with abdominopelvic tuberculosis (TB) and abnormal CA125 levels to better distinguish this disease from advanced ovarian cancer (AOC) and pelvic inflammatory disease (PID). Abdominopelvic tuberculosis (APTB) is one of the extrapulmonary tuberculosis (TB) sites, usually m...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-3034-2
更新日期：2014-03-01 00:00:00
abstract：PURPOSE:To test the reliability of the admission test to identify the compromised fetus and thus reduce the neonatal morbidity and mortality by early intervention. METHODS:A prospective analysis over a period of 1 year from December 2007 to December 2008 included 100 antepartum patients and were evaluated for perinata...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1406-4
更新日期：2010-10-01 00:00:00
abstract：:Serum levels of CA 125 were determined in 239 patients suffering from gynecological malignancies. The upper limit for normal was 35 U/ml. Raised levels were found in 82% of patients with primary ovarian carcinoma, and in 29% of those with benign ovarian tumors. The values from patients with ovarian carcinomas in parti...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF00931312
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND:Cerebral malformations may lead to permanent postnatal sequels. The antenatal detection of anomalous or absent fetal sulci and gyri may indicate abnormal brain development and future neurological and psychomotor problems in that infant. The prenatal diagnosis of these conditions allows genetic counseling, ps...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-010-1691-y
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVE:Although elective cesarean section (ECS) is the currently recommended modality for delivering women infected with the human immunodeficiency virus (HIV), historical evidence suggests that they are at higher risk of postoperative complications than noninfected women. Those risks have to be carefully balanced a...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s00404-006-0166-7
更新日期：2006-06-01 00:00:00
abstract：:In the original version of this article contained an error in figure 1. It was provided in German. ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00404-018-4785-6
更新日期：2018-07-01 00:00:00
abstract：:We present a case report about bilateral multicystic dysplastic kidneys (MCDKs). Pregnancy was terminated at 21 weeks' gestation and the fetus was examined by autopsy. The kidneys were replaced by many cysts and there was no parenchyma. However, on histological examination, there was normal nephrogenesis amid the cyst...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s004040100188
更新日期：2002-07-01 00:00:00
abstract：PURPOSE:Episiotomy is one of the most commonly performed procedures among women of childbearing age in the United States. In 2005, a major systematic review conducted by Hartmann and colleagues recommended against routine use of episiotomy and was widely covered in the media. We assessed the impact of the Hartman et al...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2904-y
更新日期：2013-12-01 00:00:00
abstract：:Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl. Serum ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s004040000114
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To investigate the precipitating factors of heart failure (HF) and to investigate the maternal and neonatal outcomes in pregnant women with HF. METHODS:We reviewed the medical records of pregnant women with HF who were treated at West China Second University Hospital between September 2012 and September 2017. ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05350-2
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:To compare the delivery and neonatal outcome of IVF singleton pregnancies with those conceived spontaneously in primiparous women ≥ 35 years of age. METHODS:Data were collected by the hospital's obstetrics and pediatric staff at the time of examination, hospitalization, delivery and discharge. A total of 283 w...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-1873-2
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of a course of corticosteroids on platelet count in both thrombocytopenic and normal pregnant women. STUDY DESIGN:We retrospectively considered 107 pregnant women at 24-34 weeks gestation, who had received betametasone treatment (12 mg i.m. for two consecutive days) for fetal lung matu...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-006-0141-3
更新日期：2006-06-01 00:00:00
abstract：PURPOSE:Acrylamide has been associated with carcinogenicity in experimental animals, but potential health risks of dietary acrylamide intake and endometrial cancer in human are inconclusive. Thus, a meta-analysis of prospective cohort studies was conducted to provide a quantitative assessment of the association between...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,meta分析
doi：10.1007/s00404-014-3595-8
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:Τo estimate the discrepancy rate between colposcopy, punch biopsy histology and surgical specimen histology as well as the positive (PPV) and negative predictive value (NPV) of colposcopic diagnosis for high-grade squamous intraepithelial lesions (HGSIL). METHODS:A prospective study was conducted during the pe...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4714-8
更新日期：2018-05-01 00:00:00
abstract：PURPOSE:To estimate the impact of increasing pre-pregnancy Body Mass Index (BMI) on the risk of adverse maternal and perinatal outcomes, in patients who delivered in an Italian tertiary care Obstetric department. METHODS:Data, related to women who delivered at Sant'Anna Hospital, Turin, between 2011 and 2015, were col...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05093-0
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Ovarian sex-cord stromal tumor (SCST) comprises 5% of the ovarian neoplasm; it occurs as an ovarian mass or hemoperitoneum, and the surgical management of SCST is not well defined at early stage and in adult patients. PURPOSE OF THE STUDY:The authors tested to test the total not radical laparoscopic managem...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1773-x
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:Angioleiomyoma is a rare benign solitary tumor, arising from the vascular smooth muscle. This tumor usually occurs in the subcutis of extremities, uncommonly in abdomen, often presents as a small (<2 cm) and is treated with excision. CASE:We report an extremely rare case of unusually large angioleiomyoma, f...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-008-0663-y
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:Color Doppler ultrasound (CDU) accuracy of kidneys and bladder in the diagnosis and treatment of hydronephrosis and/or renal colic in pregnancies was evaluated. METHODS:Between January 2010 and September 2012, 234 pregnant women asymptomatic in 204 cases and with unilateral renal colic in 30 (median 26 years) ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2768-1
更新日期：2013-09-01 00:00:00
abstract：PURPOSE:To assess changing trends, role of the triad patient-pregnancy-health professionals and health care cost in emergency peripartum hysterectomy (EPH). METHODS:Demographics, indications, perinatal outcomes, perioperative complications in EPH cases performed in a 10-year period were extracted from the local birth ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05504-7
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:The aim of this study is to assess the effects of maternal nifedipine administration on placental and fetal blood flow. METHODS:A total of 29 patients with preterm labor diagnosis admitted to the tertiary care center, Zeynep Kamil Hospital, were evaluated. Before and 24-48 h after administration of oral nifedi...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4839-9
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:The aim of this study was to determine the correlation between fetal transverse cerebellar diameter (TCD) and gestational age of male and female fetus in women under low-risk prenatal care between the 13th and 40th week of gestation. METHODS:A cross-sectional study was carried out with 184 pregnant women, at t...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1644-5
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:The objective of this study was to determine the changes in total plasma thiols (homocysteine, cysteine and cysteinylglycine), lipid peroxidation and nitric oxide concentrations during normal pregnancy. METHODS:These variables were measured in 28 uncomplicated pregnant women at first, second and third trimeste...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-2150-0
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND:Cardiac tamponade caused by gynecologic malignancies are extremely rare. CASE:A 56-year-old woman was referred to our hospital with vaginal bleeding and abdominal distension. Computed tomography showed massive peritoneal fluid, peritoneal dissemination, swelling of the paraaortic lymph nodes and liver metas...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-008-0701-9
更新日期：2009-03-01 00:00:00
abstract：:A kit using mouse monoclonal antibody against human alpha-fetoprotein (anti-AFP kit) has been developed. Cervical secretion (n = 34) and vaginal fluid (n = 15) was obtained from 30 pregnant volunteers. All 31 specimens obtained from women with intact membranes tested negative while all 18 specimens from women with pre...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF00634709
更新日期：1995-01-01 00:00:00
