Manipulation of heterogeneity product in 4'-demethylepipodophyllotoxin biotransformation process by using yeast extract as nitrogen source.

abstract：:Chlorogenate hydrolase (EC 3.1.1.42, CHase) was highly induced in mycelia of Aspergillus sojae AKU 3312 grown in Czapek medium containing either instant coffee powder or coffee pulp as inducer. No CHase formation was observed in the mycelia when cultivated without the inducer. CHase was purified readily from CHase-ind...

journal_title：Applied microbiology and biotechnology

authors： Adachi O,Ano Y,Akakabe Y,Shinagawa E,Matsushita K

更新日期：2008-11-01 00:00:00

abstract：:Pseudomonas sp. D7-4 and Pseudomonas sp. B13 FR1(pFRC20P) degraded mixtures of chloro- and methyl-substituted benzoates exclusively via an extended ortho pathway, whereas in Pseudomonas putida WR 201 both ortho and meta fission were induced by mixtures of 3-chloro- and 3-methylbenzoate or even by 3-chloro-benzoate alo...

journal_title：Applied microbiology and biotechnology

authors： Franck-Mokross AC,Schmidt E

更新日期：1998-08-01 00:00:00

abstract：:Several ansamycins have been reported to inhibit bacterial biofilm formation and accelerate the eradication of developed biofilms, but little is known about the effect of hygrocin C, an ansamycin, on bacterial biofilm formation. Here, hygrocin C was isolated from the marine-derived Streptomyces sp. SCSGAA 0027 and rep...

journal_title：Applied microbiology and biotechnology

authors： Wang J,Nong XH,Amin M,Qi SH

更新日期：2018-02-01 00:00:00

abstract：:Trehalose (α-D-glucopyranosyl-(1 → 1)-α-D-glucopyranoside) is a non-reducing disaccharide composed of two glucose molecules linked by an α,α-1,1-glycosidic bond. It possesses physicochemical properties, which account for its biological roles in a variety of prokaryotic and eukaryotic organisms and invertebrates. Inten...

journal_title：Applied microbiology and biotechnology

authors： Cai X,Seitl I,Mu W,Zhang T,Stressler T,Fischer L,Jiang B

更新日期：2018-04-01 00:00:00

abstract：:At present, more than 100 strains of Lentinula edodes are cultivated on a commercial scale in China. A simple, reliable, and effective method to distinguish some commercial strains of the superior type from other commercial strains is very important for the Lentinula industry. In this study, 23 commercial strains of L...

journal_title：Applied microbiology and biotechnology

authors： Li HB,Wu XQ,Peng HZ,Fu LZ,Wei HL,Wu QQ,Jin QY,Li N

更新日期：2008-11-01 00:00:00

abstract：:Optimization of yields and productivities in reductive whole-cell biotransformations is an important issue for the industrial application of such processes. In a recent study with Escherichia coli, we analyzed the reduction of the prochiral β-ketoester methyl acetoacetate by an R-specific alcohol dehydrogenase (ADH) t...

journal_title：Applied microbiology and biotechnology

authors： Siedler S,Bringer S,Blank LM,Bott M

更新日期：2012-02-01 00:00:00

abstract：:Cultivation processes involving filamentous fungi have been optimised for decades to obtain high product yields. Several bulk chemicals like citric acid and penicillin are produced this way. A simple adaptation of cultivation parameters for new production processes is not possible though. Models explaining the correla...

journal_title：Applied microbiology and biotechnology

authors： Grimm LH,Kelly S,Krull R,Hempel DC

更新日期：2005-12-01 00:00:00

abstract：:Due to variations in the production levels, a full-scale sequencing batch reactor (SBR) for post-treatment of tannery wastewater was exposed to low and high ammonia load periods. In order to study how these changes affected the N-removal capacity, the microbiology of the reactor was studied by a diverse set of techniq...

journal_title：Applied microbiology and biotechnology

authors： Cabezas A,Draper P,Etchebehere C

更新日期：2009-10-01 00:00:00

abstract：:α-L-Rhamnosyl-β-D-glucosidase (rutinosidase) hydrolyzes the glycosidic linkage between the disaccharide 6-O-α-L-rhamnosyl-β-D-glucoside (rutinose) and the aglycone. We identified a hypothetical protein (annotated as AO090012000917) encoded in the Aspergillus oryzae genome that exhibits sequence similarity with Aspergi...

journal_title：Applied microbiology and biotechnology

authors： Ishikawa M,Kawasaki M,Shiono Y,Koseki T

更新日期：2018-04-01 00:00:00

abstract：:To seek more information on function of two-component regulatory systems (TCSs) in Streptomyces coelicolor, a dozen TCS-knockout mutants were generated, and phenotype changes were determined. One TCS (SCO5403/5404)-deleted mutant with phenotype change was obtained. Here, we report the characterization of this novel TC...

journal_title：Applied microbiology and biotechnology

authors： Lu Y,Wang W,Shu D,Zhang W,Chen L,Qin Z,Yang S,Jiang W

更新日期：2007-12-01 00:00:00

abstract：:Certain lactic acid bacteria, especially heterofermentative strains, are capable to produce mannitol under adequate culture conditions. In this study, mannitol production by Lactobacillus reuteri CRL 1101 and Lactobacillus fermentum CRL 573 in modified MRS medium containing a mixture of fructose and glucose in a 6.5:1...

journal_title：Applied microbiology and biotechnology

authors： Rodríguez C,Rimaux T,Fornaguera MJ,Vrancken G,de Valdez GF,De Vuyst L,Mozzi F

更新日期：2012-03-01 00:00:00

abstract：:There is currently an increasing number of cytochrome P450 (CYP450) monooxygenase encoding genes becoming available from various genome-sequencing projects. These enzymes require association with cytochrome P450 reductase (CPR) to achieve optimal activities. In this study, the CYP53B1 gene, which encodes a benzoate pa...

journal_title：Applied microbiology and biotechnology

authors： Shiningavamwe A,Obiero G,Albertyn J,Nicaud JM,Smit M

更新日期：2006-09-01 00:00:00

abstract：:Recombinant production of mammalian cytoplasmic proteins plays a major role in developing pharmaceutical products. Here we describe two expression technologies using unique nature of halophilic bacteria. One of such properties of halophilic bacteria is accumulation of compatible solutes in the cytoplasm. As the compat...

journal_title：Applied microbiology and biotechnology

authors： Tokunaga H,Arakawa T,Tokunaga M

更新日期：2010-12-01 00:00:00

abstract：:A simple structured model for the dynamics of phosphate-limited batch fermentations with Streptomyces tendae is presented. The model describes the influence of intracellular phosphate storage upon the growth behav our of the culture. The development of the model takes into account the possible internal regulatory proc...

journal_title：Applied microbiology and biotechnology

authors： Mundry C,Kuhn KP

更新日期：1991-06-01 00:00:00

abstract：:In Catharanthus roseus cell cultures the time courses of four enzyme activities, tryptophan decarboxylase (TDC), strictosidine synthase (SSS), geraniol-10-hydroxylase (G10H) and anthranilate synthase (AS), and alkaloid accumulation were compared under two different culture conditions (low-inoculum density and high-ino...

journal_title：Applied microbiology and biotechnology

authors： Moreno PR,Schlatmann JE,van der Heijden R,van Gulik WM,ten Hoopen HJ,Verpoorte R,Heijnen JJ

更新日期：1993-04-01 00:00:00

abstract：:The long-term usage of antibiotics has resulted in the evolution of multidrug-resistant bacteria. Unlike antibiotics, anti-virulence approaches target bacterial virulence without affecting cell viability, which may be less prone to develop drug resistance. Staphylococcus aureus is a major human pathogen that produces ...

journal_title：Applied microbiology and biotechnology

authors： Lee K,Lee JH,Kim SI,Cho MH,Lee J

更新日期：2014-11-01 00:00:00

abstract：:Bacteria from the genus Geobacillus are generally obligately thermophilic, with a unique bioenergy production capacity and unique enzymes. Geobacillus species were isolated primarily from hot springs, oilfields, and associated soils. They often exhibit unique survival patterns in these extreme oligotrophic environment...

journal_title：Applied microbiology and biotechnology

authors： Lin JH,Zhang KC,Tao WY,Wang D,Li S

更新日期：2019-10-01 00:00:00

abstract：:Under alternating aerobic/anaerobic conditions and without additional carbon sources, a bacterial consortium consisting initially of 18 bacterial strains was obtained in a sequence batch reactor. The phosphorus removal capability could only be maintained using sterile filtrate of activated sludge as medium. The additi...

journal_title：Applied microbiology and biotechnology

authors： Hollender J,Dreyer U,Kornberger L,Kämpfer P,Dott W

更新日期：2002-01-01 00:00:00

abstract：:Evolvulus alsinoides L. is used for preparation of 'Shankhapushpi', an important popular ayurvedic drug that contributes considerably to the improvement of memory power. The improvement is attributed to the presence of furanocoumarin scopoletin, a metabolite with a wide range of biological activities. This report desc...

journal_title：Applied microbiology and biotechnology

authors： Naikawadi VB,Ahire ML,Lahiri A,Nikam TD

更新日期：2016-04-01 00:00:00

abstract：:Vitamin B12 is an essential nutrient required for crucial metabolic processes in humans. Vitamin B12-producing lactic acid bacteria (LAB) have been attracting increased attentions currently because of the generally recognized as safe (GRAS) status. Most of recent studies focused on Lactobacillus, and little is known a...

journal_title：Applied microbiology and biotechnology

authors： Li P,Gu Q,Wang Y,Yu Y,Yang L,Chen JV

更新日期：2017-08-01 00:00:00

abstract：:The present study reports the successful production of human pre-miR-29b both intra- and extracellularly in the marine phototrophic bacterium Rhodovulum sulfidophilum using recombinant RNA technology. In a first stage, the optimal transformation conditions (0.025 μg of plasmid DNA, with a heat-shock of 2 min at 35 °C)...

journal_title：Applied microbiology and biotechnology

authors： Pereira P,Pedro AQ,Tomás J,Maia CJ,Queiroz JA,Figueiras A,Sousa F

更新日期：2016-04-01 00:00:00

abstract：:A bacterial biofilm, capable of mineralising a technical mixture of cis- and trans-1,3-dichloropropene (DCPE), was enriched on the biomedium side of an extractive membrane biofilm reactor (EMBR). The membrane separates the biomedium from the industrial waste water, in terms of pH, ionic strength and the concentration ...

journal_title：Applied microbiology and biotechnology

authors： Katsivela E,Bonse D,Krüger A,Strömpl C,Livingston A,Wittich RM

更新日期：1999-11-01 00:00:00

abstract：:Diastereoselective reduction of diketones with Lactobacillus kefir DSM 20587 was examined. The reduction of both oxo-functions proceeded highly diastereoselectively. (2 R,5 R)-Hexanediol 3 was produced starting from (2,5)-hexanedione 1 in quantitative yields with enantiomeric excess >99% and diastereomeric excess >99%...

journal_title：Applied microbiology and biotechnology

authors： Haberland J,Kriegesmann A,Wolfram E,Hummel W,Liese A

更新日期：2002-04-01 00:00:00

abstract：:Pseudomonas rhodesiae KK1 was isolated from a former manufactured-gas plant site, due to its ability to grow rapidly in a mixture of polycyclic aromatic hydrocarbons (PAHs). Radiorespirometric analysis revealed that strain KK1 was found to be able to mineralize anthracene, naphthalene and phenanthrene. Notably, phenan...

journal_title：Applied microbiology and biotechnology

authors： Kahng HY,Nam K,Kukor JJ,Yoon BJ,Lee DH,Oh DC,Kam SK,Oh KH

更新日期：2002-12-01 00:00:00

abstract：:2-Phenylethanol (2-PE) is an important flavor compound but also impairs cell growth severely, which in turn blocks its bioproduction. However, the molecular mechanism of 2-PE tolerance is unclear. In this study, a superb 2-PE stress-tolerant and producing yeast, Candida glycerinogenes, was selected to uncover the unde...

journal_title：Applied microbiology and biotechnology

authors： Wang Y,Zhang Z,Lu X,Zong H,Zhuge B

更新日期：2020-05-01 00:00:00

abstract：:Acyl-CoAs are crucial compounds involved in essential metabolic pathways such as the Krebs cycle and lipid, carbohydrate, and amino acid metabolisms, and they are also key signal molecules involved in the transcriptional regulation of lipid biosynthesis in many organisms. In this study, we took advantage of the high s...

journal_title：Applied microbiology and biotechnology

authors： Cabruja M,Lyonnet BB,Millán G,Gramajo H,Gago G

更新日期：2016-08-01 00:00:00

abstract：:Four potential dehydrogenases identified through literature and bioinformatic searches were tested for L-arabonate production from L-arabinose in the yeast Saccharomyces cerevisiae. The most efficient enzyme, annotated as a D-galactose 1-dehydrogenase from the pea root nodule bacterium Rhizobium leguminosarum bv. trif...

journal_title：Applied microbiology and biotechnology

authors： Aro-Kärkkäinen N,Toivari M,Maaheimo H,Ylilauri M,Pentikäinen OT,Andberg M,Oja M,Penttilä M,Wiebe MG,Ruohonen L,Koivula A

更新日期：2014-12-01 00:00:00

abstract：:N-acetyl glutamate kinase (NAGK) is a key enzyme in the synthesis of L-arginine that is inhibited by its end product L-arginine in Corynebacterium glutamicum (C. glutamicum). In this study, the potential binding sites of arginine and the residues essential for its inhibition were identified by homology modeling, inhib...

journal_title：Applied microbiology and biotechnology

authors： Huang Y,Zhang H,Tian H,Li C,Han S,Lin Y,Zheng S

更新日期：2015-09-01 00:00:00

abstract：:On a near future, bio-based economy will assume a key role in our lives. Lignocellulosic materials (e.g., agroforestry residues, industrial/solid wastes) represent a cheaper and environmentally friendly option to fossil fuels. Indeed, following suitable processing, they can be metabolized by different microorganisms t...

journal_title：Applied microbiology and biotechnology

authors： Gomes D,Rodrigues AC,Domingues L,Gama M

更新日期：2015-05-01 00:00:00

abstract：:Seven fractions rich in endoglucanase activity were separated from the extracellular cellulase system of the anaerobic rumen fungus Neocallimastix frontalis. The fractions (ES1, ES3, ES2U1, ES2U2, ES2U4, ES2U3C1 and ES2U3C2) were separated from each other and from a fraction that could solubilize crystalline cellulose...

journal_title：Applied microbiology and biotechnology

authors： Wood TM,Wilson CA,McCrae SI

更新日期：1995-12-01 00:00:00