Importance of worldwide asymptomatic carriers of Leishmania infantum (L. chagasi) in human.

Abstract:

:Leishmaniasis due to Leishmania infantum (syn. L. chagasi) infection is a zoonotic disease present mainly in Mediterranean basin, central Asia and Brazil. Besides a limited number of human cases of clinical visceral leishmaniasis, a great number of infections remains asymptomatic. In this review, the prevalence of asymptomatic carriers of L. infantum was evaluated worldwide using parasitological methods or indirect testing such as a skin test or serology. The consequences of the presence of asymptomatic carriers on parasite transmission by blood donation or the development of clinical visceral leishmaniasis in immunocompromised individuals and its possible role as reservoir are discussed.

journal_name

Acta Trop

journal_title

Acta tropica

authors

Michel G,Pomares C,Ferrua B,Marty P

doi

10.1016/j.actatropica.2011.05.012

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

69-75

issue

2-3

eissn

0001-706X

issn

1873-6254

pii

S0001-706X(11)00176-8

journal_volume

119

pub_type

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