Abstract：
:Numerical alterations of circulating lymphocytes were investigated in 37 Brazilian patients with uncomplicated Plasmodium falciparum malaria and in a group of 15 healthy controls. The number of CD4+ T helper/inducer cells was significantly lower in patients than controls, whereas absolute numbers of CD8+ suppressor/cytotoxic T cells did not differ between the groups. TNF and neopterin levels were markedly increased in the plasma of patients and remained slightly elevated after chemotherapy with clindamycin. Neopterin, but not TNF levels, were significantly correlated with parasitaemia. TNF was inversely related to monocyte counts. Interferon gamma could not be detected in the plasma of control subjects and was observed in only one patient. We conclude that in uncomplicated falciparum malaria the distribution of phenotypes of circulating lymphocytes are altered slightly and that the high plasma levels of TNF and neopterin indicate excessive release of these molecules by activated macrophages and the activation of cellular immune mechanisms during the infection.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Kremsner PG,Feldmeier H,Zotter GM,Jansen-Rosseck R,Graninger W,Rocha RM,Bienzle Udoi
10.1016/0001-706x(89)90047-8subject
Has Abstractpub_date
1989-10-01 00:00:00pages
351-9issue
5-6eissn
0001-706Xissn
1873-6254pii
0001-706X(89)90047-8journal_volume
46pub_type
杂志文章相关文献
ACTA TROPICA文献大全abstract：:During an epidemic of cutaneous leishmaniais in northeast Brazil a prospective study was conducted in order to assess clinical, parasitological and immunological features of cutaneous leishmaniasis in a representative sample of patients. A general examination was done and demographic and anthropometric data as well as...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2005.01.003
更新日期：2005-03-01 00:00:00
abstract：:Domestic reinfestations by triatomine bugs were monitored after application of deltamethrin and apparent elimination of Triatoma infestans in Amama and other nearby rural villages, north-west Argentina, from 1992 to 1996. The five methods used were sensor boxes, sheets of pink typing-paper, timed manual catches by a s...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(98)00096-5
更新日期：1999-03-15 00:00:00
abstract：:The fluid mechanics of the flow of blood through the labrum of Glossina is described in uninfected and trypanosome infected flies. The flow is characterised by the Reynolds number, and a frequency parameter for the pulsating flow and non-newtonian viscosity effects are considered. The effects of colonies of trypanosom...
journal_title：Acta tropica
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：:We conducted the first meta-analysis of ten Schistosoma haematobium (one published and nine unpublished) and eight Schistosoma mansoni (two published and six unpublished) microsatellite datasets collected from individual schistosome-infected school-children across six sub-Saharan Africa countries. High levels of genet...
journal_title：Acta tropica
pub_type： 杂志文章,meta分析
doi：10.1016/j.actatropica.2012.09.014
更新日期：2013-11-01 00:00:00
abstract：:Glanders is an infectious and contagious bacterial disease of equines. A little is known about its seroprevalence and risk factors in working equines in countries where the disease is endemic. Also, there are no reports on prevalence of the disease in areas where there is a prior evidence of Burkholderia (B.) mallei d...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2017.07.031
更新日期：2017-12-01 00:00:00
abstract：:Primaquine has been the drug of choice for the prevention of Plasmodium vivax relapse for more than 60 years. Primaquine tolerant strain of P. vivax was identified in 1944. Significant mortality and disease burden of P. vivax calls for the need of new drugs. Primaquine resistance is a complex issue, as the mechanism o...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/j.actatropica.2016.04.009
更新日期：2016-08-01 00:00:00
abstract：:A study was conducted to determine the presence of hemagglutination inhibition (HI) and neutralization antibodies against Japanese encephalitis virus (JEV) in wild pigs on an offshore island in Singapore. Blood samples were collected from 28 wild pigs on the island. All the sera tested with HI assay and plaque reducti...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(01)00212-1
更新日期：2002-03-01 00:00:00
abstract：:An experiment was conducted to determine, under different conditions, the capacity of young adult East African goats to eliminate intravenously inoculated [75Se]selenomethionine-labelled Trypanosoma brucei from the bloodstream. Over 80% of labelled trypanosomes, preincubated for 1 h in inactivated normal goat serum, w...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/0001-706x(89)90003-x
更新日期：1989-03-01 00:00:00
abstract：:Preliminary data from an ongoing epidemiological survey in the pastoral zone of Samorogouan (Kénédougou) indicate the occurrence of multiple-drug-resistant Trypanosoma congolense. Despite frequent trypanocidal drug treatments with diminazene aceturate (Berenil, Hoechst) at 7 mg/kg body weight (bw) at intervals of 2 to...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/0001-706x(92)90041-u
更新日期：1992-08-01 00:00:00
abstract：:Chagas disease, caused by Trypanosoma cruzi affects about 6-8 million people worldwide. Although transmission by triatomine insects has been controlled, other means of transmission maintain the infection. These forms of transmission are responsible for introducing Chagas disease in other non-endemic countries of the w...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2017.08.025
更新日期：2017-12-01 00:00:00
abstract：:The biological control of schistosomiasis has already proven its efficiency in several habitats in the Caribbean area. Two main types of biological control agents, either trematode parasites or competitor snails have been studied and tested against the snail hosts of schistosomiasis in this region. The first one, Ribe...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(00)00123-6
更新日期：2000-10-23 00:00:00
abstract：:"Anomalous", as yet unreported forms of brood capsules (BC) in cystic echinococcosis larvae from humans and sheep are described, thought to be the likely effect of degenerative involution of the parasite. Morphological examination showed an inner laminated layer (LL) in the brood capsules in intimate contact with the ...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2007.12.006
更新日期：2008-03-01 00:00:00
abstract：:Symptomatic chronic Chagas disease affects up to 40% of patients infected with Trypanosoma cruzi. The lack of reliable early markers of cure after therapy hinders disease management and clinical trials with new drugs. We performed a study with 18 months of follow-up to compare changes in immune parameters and T. cruzi...
journal_title：Acta tropica
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.actatropica.2016.09.010
更新日期：2016-12-01 00:00:00
abstract：:Omega-3 and omega-6 polyunsaturated fatty acids are synthesized from the essential fatty acids alpha-linolenic acid and linoleic acid, respectively. They are pivotal components of all mammalian cells and were found to be useful in prevention and treatment of a variety of health problems owing to their anti-inflammator...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/j.actatropica.2020.105466
更新日期：2020-07-01 00:00:00
abstract：:Cysticercosis caused by the larvae of Taenia solium is a serious and emerging threat to public health in the endemic areas as well as in the non-endemic areas. Neurocysticercosis, an affection of the central nervous system is a leading cause of epilepsy in endemic areas. This study was carried out to investigate human...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2015.12.019
更新日期：2017-01-01 00:00:00
abstract：:The coadministration of tubercidin and ethidium to mice infected with Trypanosoma gambiense gave a better parasite clearance than either of the single drugs. The combination was also more toxic to the mice but the inclusion of nitrobenzylthioinosinate in the therapy significantly alleviated the toxicity of the drug co...
journal_title：Acta tropica
pub_type： 杂志文章
doi：
更新日期：1982-09-01 00:00:00
abstract：:The diagnosis of neurocysticercosis was greatly improved by the introduction of computed tomography (CT) and magnetic resonance imaging (MRI). These techniques demonstrate the number and topography of lesions, their stage of involution, and the degree of inflammatory reaction of the host against the parasites and have...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/s0001-706x(03)00057-3
更新日期：2003-06-01 00:00:00
abstract：:The main objective of the present study was to evaluate the potential of eriosematin E (ECM) isolated from the roots of Eriosema chinense against enteropathogenic Escherichia coli (EPEC) induced diarrhoea. ECM isolated from the bioactive chloroform fraction of E. chinense was subjected to antidiarrhoeal evaluation on ...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2019.02.025
更新日期：2019-05-01 00:00:00
abstract：:This study aimed to investigate the prevalence of cercarial infections in freshwater snails collected from the Chai Nat province of Central Thailand. Moreover, we aimed to develop a duplex PCR technique, using the ITS2 and candidate MT-ND1 gene, to determine the dissemination of H. taichui and H. pumilio, respectively...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2020.105795
更新日期：2020-12-10 00:00:00
abstract：:While Burkholderia pseudomallei, the causative agent of melioidosis, is becoming increasingly recognized as a significant cause of morbidity and mortality in regions to which it is endemic, no licensed vaccine preparation currently exists for immunization against the disease. Therefore, one of the primary goals of our...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/s0001-706x(99)00071-6
更新日期：2000-02-05 00:00:00
abstract：:The identification and characterization of Leishmania are relevant to diagnosis, treatment, eco-epidemiology studies, prophylactic measures and control of the disease. Two strains of Leishmania (MHOM/BR/1971/BH49 and MHOM/BR/1971/BH121), isolated from human cutaneous leishmaniasis, were studied using biological and mo...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2009.07.026
更新日期：2009-12-01 00:00:00
abstract：:In the present investigation, it has been demonstrated that cattle become resistant to ticks after several heavy infestations, particularly with B. microplus. During development of the infestations, antibodies against salivary glands of B. microplus were detected using 2 techniques: indirect immunofluorescence and imm...
journal_title：Acta tropica
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Bashagard is an important malaria endemic area in south of Iran. An epidemiological and entomological survey was performed during 2002-2010. The aim of study was to determine malaria situation, species composition of anopheline mosquitoes and susceptibility status of main vectors to insecticides/larvicides. A total of...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2011.04.017
更新日期：2012-02-01 00:00:00
abstract：:The blood-feeding behaviour of nymphs and adults of Triatoma brasiliensis fed on the forearm of human volunteers was studied by electronic monitoring of the cibarial pump. Parameters of total contact time (TT), initial weight (IW), weight gain (WG), ingestion rate (IR), pump frequency (F), quantity of liquid ingested ...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(03)00121-9
更新日期：2003-08-01 00:00:00
abstract：:Coxiellosis is a zoonotic disease caused by the ubiquitous bacteria Coxiella burnetii, which can be spread either through ticks or through body fluids. In humans the infection is characterized by a febrile disease; ruminants may abort and reduce their milk yield, causing serious production losses for the farmer. In In...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2019.03.022
更新日期：2019-06-01 00:00:00
abstract：:Ultracytochemistry of polysaccharides and specific sugar residues reveals differences in the surface staining pattern between developmental forms of Trypanosoma brucei. The techniques used were the PA (periodic acid)-TCH (thiocarbohydrazide)-silver albumose reaction for the polysaccharides, and the Concanavalin A (Con...
journal_title：Acta tropica
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:Dicrocoelium dendriticum (Rudolphi, 1819) and Dicrocoelium hospes (Looss, 1907) are recognised to affect the liver of domestic and wild ruminants. A third species, Dicrocoelium orientalis which was described from musk deer in the Baikal region of the former Soviet Union and re-named to Dicrocoelium chinensis (Sudariko...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2007.07.008
更新日期：2007-11-01 00:00:00
abstract：:As strictly haematophagous insects, tsetse flies feed on a wide variety of wild and domestic animals. Although these are mainly mammals, some tsetse species also feed on reptiles. The present study investigated whether the odours of several potential natural tsetse hosts may be used as novel attractants to improve the...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(97)00083-1
更新日期：1997-11-01 00:00:00
abstract：:The water-related exposome is a significant determinant of human health. The disease burden through water results from water-associated communicable and non-communicable diseases and is influenced by water pollution with chemicals, solid waste (mainly plastics), pathogens, insects and other disease vectors. This paper...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/j.actatropica.2019.03.011
更新日期：2019-05-01 00:00:00
abstract：:Infection with the protozoan parasite Trypanosoma cruzi, the etiologic agent of human Chagas disease, results in life-long infection. Infective trypomastigotes circulate in the bloodstream and have the capacity to infect any cell type, including reproductive tissue. This study sought to assess the potential for sexual...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2015.05.002
更新日期：2015-09-01 00:00:00
