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Expression of Mmachc and Mmadhc during mouse organogenesis.

Abstract：

:To examine whether Mmachc and Mmadhc, two genes involved in vitamin B(12) (cobalamin) metabolism, show tissue-specific expression during mouse embryogenesis, we determined their sites of expression at 11.5days post conception by in situ hybridization. There was ubiquitous expression of Mmadhc, but tissue and cell type-specific expression of Mmachc in the developing lung, heart, cardiovascular and nervous system. This suggests that during organogenesis Mmachc and Mmadhc may interact in only a subset of cells.

journal_name

Mol Genet Metab

journal_title

Molecular genetics and metabolism

authors

Pupavac M,Garcia MA,Rosenblatt DS,Jerome-Majewska LA

doi

10.1016/j.ymgme.2011.04.004

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

401-5

issue

4

eissn

1096-7192

issn

1096-7206

pii

S1096-7192(11)00119-3

journal_volume

103

pub_type

杂志文章

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