5-oxo-15-HETE: total synthesis and bioactivity.

Abstract:

:The first total synthesis of 6(E),8(Z),11(Z),13(E) 5-oxo-15-HETE 4 was accomplished. The synthetic material was evaluated with calcium mobilization assay and compared with 5-oxo-ETE the natural ligand for the OXE receptor.

journal_name

Bioorg Med Chem Lett

authors

Patel P,Anumolu JR,Powell WS,Rokach J

doi

10.1016/j.bmcl.2011.01.032

subject

Has Abstract

pub_date

2011-03-15 00:00:00

pages

1857-60

issue

6

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(11)00045-X

journal_volume

21

pub_type

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