Dihydropyrazolopyrimidine inhibitors of K(V)1.5 (I(Kur)).

Abstract:

:A series of dihydropyrazolopyrimidine inhibitors of K(V)1.5 (I(Kur)) have been identified. The synthesis, structure-activity relationships and selectivity against several other ion channels are described.

journal_name

Bioorg Med Chem Lett

authors

Vaccaro W,Huynh T,Lloyd J,Atwal K,Finlay HJ,Levesque P,Conder ML,Jenkins-West T,Shi H,Sun L

doi

10.1016/j.bmcl.2008.10.099

subject

Has Abstract

pub_date

2008-12-15 00:00:00

pages

6381-5

issue

24

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(08)01291-2

journal_volume

18

pub_type

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