Megavoltage therapy of glioblastoma multiforme.

Abstract:

:Supervolt radiation therapy produced no improved survival rates in the treatment of glioblastoma multiforme as compared to orthovolt therapy. Survival times of more than one year or two years must still be considered a rarity. The application of computer techniques to the calculation of dose distributions greatly enhances the optimization of treatment planning. Tumour doses of 5,000 to 7,000 rad are considered necessary, and are dangerously close to the dose levels tolerated by brain tissue. Improvements could conceivably be expected from a) combinations of chemotherapy and radiation therapy, b) intra-arterial application of radiating substances with tumour affinity, c) neutron therapy. Whether or not such measures will in the future produce improved therapeutic results remains to be seen.

journal_name

Acta Neurochir (Wien)

journal_title

Acta neurochirurgica

authors

Kahr E

doi

10.1007/BF01406633

subject

Has Abstract

pub_date

1978-01-01 00:00:00

pages

79-87

issue

1-2

eissn

0001-6268

issn

0942-0940

journal_volume

42

pub_type

杂志文章
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    pub_type: 杂志文章,meta分析

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    doi:10.1007/s00701-007-1447-z

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    更新日期:2008-02-01 00:00:00

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    更新日期:2010-10-01 00:00:00

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    authors: Benzagmout M,Chaoui Mel F,Duffau H

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    doi:10.1007/BF01809265

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    pub_type: 杂志文章

    doi:10.1007/BF01403492

    authors: Lüdecke DK,Lutz BS,Niedworok G

    更新日期:1989-01-01 00:00:00

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    更新日期:2002-09-01 00:00:00

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