Abstract:
BACKGROUND:Impairment of cerebral autoregulation is known to adversely affect outcome following traumatic brain injury (TBI). The phase shift (PS) method of cerebral autoregulation (CA) assessment describes the time lag between fluctuations in arterial blood pressure (ABP) and cerebral blood flow velocity (CBFV) in the middle cerebral artery. An alternative method (Mx-ABP) is based on the statistical correlation between ABP and CBFV waveforms over time. We compared these two indices in a cohort of severely head injured patients undergoing controlled, 6-breaths-per-minute ventilation. METHODS:PS and Mx-ABP were calculated from 33 recordings of CBFV and MAP in 22 patients with TBI. Spearman's correlation coefficient was used to assess the agreement between PS and Mx-ABP. The relationship between ICP slow wave amplitude, MAP slow wave amplitude and mean ICP was also examined. FINDINGS:Mean values for Mx-ABP and PS were 0.44 +/- 0.27, and 49 +/- 26 (degrees), respectively. PS correlated significantly with Mx-ABP (r = -0.648, p < 0.001). A Bland-Altman plot of normalised Mx-ABP and Phase Shift values showed no significant bias or relationship (mean difference = 0.0004, r = -0.037, p = 0.852). During the test procedure, ICP fluctuated in an approximately sinusoidal fashion, with a mean amplitude of 4.96 +/- 2.72 mmHg (peak to peak). The magnitude of ICP fluctuation during deep breathing correlated weakly but significantly with mean ICP (r = 0.391, p < 0.05) and with the amplitude of ABP fluctuations (r = 0.625, p < 0.0005). CONCLUSIONS:Phase shift and Mx-ABP in TBI are well correlated. Deep breathing presents as an effective tool with which to assess autoregulation using the phase shift method.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Lewis PM,Rosenfeld JV,Diehl RR,Mehdorn HM,Lang EWdoi
10.1007/s00701-007-1447-zsubject
Has Abstractpub_date
2008-02-01 00:00:00pages
139-46; discussion 146-7issue
2eissn
0001-6268issn
0942-0940journal_volume
150pub_type
杂志文章abstract:BACKGROUND:Cerebral ischemia is considered a key factor in the development of secondary damage after Traumatic Brain Injury (TBI). Studies on Cerebral Blood Flow (CBF) have documented decreased flow in over 50% of patients with TBI, studied in the acute phase. Transcranial Doppler (TCD) sonography is a non-invasive tec...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-002-1012-8
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:The diagnosis of Chiari 1 malformation is based on the extent of tonsillar ectopia. OBJECTIVE:To examine the relationship between the extent of tonsillar ectopia and the intra-operative findings and clinical outcome following Chiari decompression surgery. METHODS:Patients were divided into four groups depe...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-04172-0
更新日期:2020-07-01 00:00:00
abstract::The radiological aspect, pathology, treatment and results of 132 subdural haematomas observed in 100 patients, are discussed. The majority of these cases were characterized by a nonhomogenous CT scan picture, resulting from repeated bleeding in a previous subdural haematoma evolving to chronicity, or in a pre-existent...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02188772
更新日期:1995-01-01 00:00:00
abstract::The authors outline the possible approaches to vertebromedullary tumours of the thoraco-lumbar spine using unilateral or bilateral transverso-arthro-pediculectomy and corporectomy. In a personal series of 20 cases. The technique and indications are described and the results. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01456263
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Intraoperative fluorescence angiography with indocyanine green (ICG) as a tracer has recently been introduced as a novel technique for neurosurgery. We evaluated the feasibility and efficacy of near-infrared (NIR) indocyanine green (ICG) videoangiography for patients undergoing carotid endarterectomy (CEA). ...
journal_title:Acta neurochirurgica
pub_type: 临床试验,杂志文章
doi:10.1007/s00701-011-1018-1
更新日期:2011-08-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to evaluate the effect of endovascular treatment of ruptured dissecting aneurysms of the vertebral artery, the benefits of early embolization, and the predictors of outcomes. CLINICAL MATERIAL AND METHODS:Between September, 2001 and May, 2009, 25 patients with ruptured verteb...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-010-0683-9
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Circumferential intradural spinal meningiomas are exceptionally rare. They pose several surgical challenges and a complete excision is not easy. The aim of this study is to provide surgical strategies to facilitate a full excision of such tumors. METHODS:A fully circumferential intradural meningioma at T9/1...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3354-2
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:The practice of endoscopic endonasal surgery is still limited in children because of the relative rarity of sellar lesions in the paediatric population. However, such an approach is increasingly reported in the literature as an alternative option to standard sublabial microsurgery, and its surgical results a...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-010-0929-6
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:The use of distal filter protection alone is associated with a high risk of ischemic complications when vulnerable carotid stenosis is treated by carotid artery stenting (CAS). Double balloon protection, a combination of distal balloon protection and proximal balloon occlusion, can be utilized. We assessed t...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-2816-2
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Hydrocephalus may present with heterogeneous signs and symptoms. The indication for its treatment and the optimal drainage in complex cases may be challenging. Telemetric intracranial pressure measurements (TICPM) may open new perspectives for those circumstances. We report our experiences using the Neuroven...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-020-04421-7
更新日期:2020-10-01 00:00:00
abstract::The aetiology of incomplete adrenergic denervation and reduction in the number and caliber of the cerebral vessels in hydrocephalus is still obscure. Stretching of the blood vessels alone is far from explaining these major vascular changes. Previous studies have shown that increased lipid peroxidation produces toxic e...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405185
更新日期:1993-01-01 00:00:00
abstract::Rats were inoculated with staphylococcus aureus to produce cerebral abscesses and treated with either antibiotic or dexamethasone and with antibiotic plus dexamethasone at sequential stages of abscess formation. Antibiotic alone shortened the cerebritis stage, accelerated the encapsulation and affected the bacterial c...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01456174
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:The effect of anterior cervical discectomy without fusion (ACD), ACD with fusion by stand-alone cage (ACDF) or with arthroplasty (ACDA) on cervical sagittal alignment is not known and is the subject of this study. METHODS:A total of 142 adult patients with single-level cervical disease were at random alloca...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00701-017-3312-z
更新日期:2017-12-01 00:00:00
abstract::Eosinophilic granuloma (EG) is a rare disease but is more common in adults than children. It's often self-limiting. Spinal involvement is rare. It is the localized and most benign form of Langerhans' cell histiocytosis (previously known as histiocytosis X), characterised by lytic lesions in one or more bones. Spontane...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-003-0182-3
更新日期:2004-02-01 00:00:00
abstract::Although primary treatment of medulloblastoma is now successful in a high percentage of patients, its secondary manifestations still bear a poor prognosis. Thorough studies of secondary manifestations are therefore pivotal to plan therapeutic approaches for the long-term management of medulloblastoma. Here we describe...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01410612
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:To investigate characteristic clinical and radiological features of extradural arachnoid cysts (EDACs) in the thoracolumbar region, a retrospective review of medical records and imaging studies was performed. EDACs are well known but relatively rare lesions in the thoracolumbar spinal canal. The most common ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-011-1110-6
更新日期:2012-02-01 00:00:00
abstract::Superficial radial intraneural ganglion cysts are rare. Only nine previous cases have been described. We provide two examples with a wrist joint connection and review the literature to provide further support for the unifying articular (synovial) theory for the pathogenesis and treatment of intraneural ganglia. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-018-3715-5
更新日期:2018-12-01 00:00:00
abstract::The authors report on the results obtained on a series of 325 patients operated on for single brain metastasis at the Institute of Neurosurgery of the University of Rome during the period 1951-1979. After analyzing the results vis-à-vis the site of the brain metastasis, the site of the primitive tumour and the surgica...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401183
更新日期:1983-01-01 00:00:00
abstract::Selection of the approach and technique for surgical repair of aneurysm of the vertebrobasilar artery system is mainly based on angiographic features. This report emphasizes that planning the surgical procedure should also include preoperative evaluation of the individual skull base configuration, as well as the relat...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01428505
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:The use of endoscopes in transnasal surgery offers increased visualization. To minimize rhinological morbidity without restriction in manipulation, we introduced the mononostril transethmoidal-paraseptal approach. METHODS:The aim of the transethmoidal-paraseptal approach is to create sufficient space within...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3075-6
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:To determine its roles in the diagnosis and the systemic evaluation of metastatic brain tumours, whole-body positron emission tomography (PET) using [18F]FDG was performed in 20 consecutive patients. METHODS:All patients were thought to be suffering or needing to be differentiated from metastatic brain tumo...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050161
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Many high-grade glioma (HGG) patients have cognitive impairments, which impact daily functioning. Cognitive impairments can be caused by tumour-, treatment-, and patient-related factors. The effect of the tumour and of surgical resection on cognition is, however, not well known. We investigated tumour and su...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-014-2115-8
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Catheter-assisted Guglielmi detachable coiling (CAGDC) is a technical option that was developed to allow the endovascular treatment of wide-necked aneurysms. We report upon our experiences of the CAGDC in treating aneurysms with an assessment of its efficacy and safety. METHODS:The effect of CAGDC of wide-n...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-006-0881-7
更新日期:2006-10-01 00:00:00
abstract:INTRODUCTION:Desmoid-type fibromatosis (DTF) frequently arises in patients with neuromuscular choristoma (NMC). We hypothesize that NMC-associated DTF occurs in soft tissues innervated by the NMC-affected nerve, and arises from CTNNB1-mutated (myo) fibroblasts within or directly adjacent to the NMC. MATERIALS AND METH...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-04178-8
更新日期:2020-05-01 00:00:00
abstract::The blocking effect of ketanserin, a 5-hydroxytryptamine (5-HT)2 receptor antagonist, was examined on responses to intra-luminal 5-HT or potassium chloride (KCl) in isolated and perfused canine basilar arteries before and after extraluminal whole blood by means of the stainless-steel cannula inserting method. Four hou...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01412316
更新日期:1996-01-01 00:00:00
abstract::During a period of 10 years (1977-1986) 40 cases of tumour of the pineal region have been treated at the Istituto Neurologico "C. Besta"-of Milan. Out of these 40 cases, 27 (67.5%) were in the paediatric (10-15 years) or juvenile (15-20 years) age at the time of operation. Since 1983 a specific diagnostic and therapeu...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01403491
更新日期:1989-01-01 00:00:00
abstract::The present study is aimed at examining the therapeutic effect of Nicorandil on chronic vasospasm using beagle dogs subjected to a "two-haemorrhage" insult, as well as its dilatory effect on the PDA [phorbol-12,13 diacetate]-induced contraction of the canine basilar artery. 1. A total of 12 animals of either sex, weig...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01476428
更新日期:1994-01-01 00:00:00
abstract::Diffuse brain injury in rabbits was caused by injecting olive oil and saline into one internal carotid artery. In this report, the fourth of a series, the effects of this experimental brain injury on respiration and acid-base balance of blood are analyzed. The animals that withstood the injury best were those that had...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405898
更新日期:1975-01-01 00:00:00
abstract:PURPOSE:To analyse the intraoperative complications of a single neurosurgeon, with emphasis on devastating intraoperative incidents, and how they possibly could have been avoided. METHODS:All the patients operated upon by the author between 1986 and 2002, i.e. 252 patients with 270 craniotomies for 294 aneurysms, were...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-009-0452-9
更新日期:2009-09-01 00:00:00
abstract::An infrared based frameless stereotactic navigation device (Easy Guide Neuro) was investigated for its clinical applicability, registration/application accuracy and limitations in a standard operating room set-up. In a five-month period 40 frameless stereotactic procedures (23 female, 17 male, mean age 46.4, yrs range...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02750999
更新日期:1997-01-01 00:00:00