Abstract：
PURPOSE:We present the results of the visualisation of radial oxygen gradients in rats' cortices and their potential use in neurocritical management. METHODS:PO₂ maps of the cortex of ten sedated, intubated and controlled ventilated Wistar rats were obtained with a camera (SensiMOD, PCO, Kelheim, Germany). Those pictures were analysed and edited by a custom-made software. A virtual matrix, designed to evaluate the cortical O₂ partial pressure, was placed vertically to the artery under investigation, and afterwards multiple regions of interest were measured (width 10 pixels, length 15-50 pixels). The results showed a map of the cerebral oxygenation, which allowed us to calculate radial oxygen gradients over arterioles. Three groups were defined according to the level of the arterial pO₂: PaO₂ < 80, PaO₂ 80-120 and PaO₂ > 120. Gradients were analysed from the middle of the vessel to its border (1), from the border into the parenchyma next to the vessel (2) and a combination of both (3). RESULTS:Gradient 1 showed significantly different cortical pO₂ values between the three different groups. The mean pO₂ values were 2.62, 5.29 and 5.82 mmHg/mm. Gradient 2 measured 0.56, 0.90 and 1.02 mmHg/mm respectively. Gradient 3 showed significant results between the groups with values of 3.18, 6.19 and 6.84 mmHg/mm. CONCLUSION:Using these gradients, it is possible to describe and compare the distribution of oxygen to the brain parenchyma. With the presented technique, it is possible to detect pO₂ changes in the oxygen supply of the brain cortex.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Galler M,Moritz S,Liebsch G,Woertgen C,Brawanski A,Warnat Jdoi
10.1007/s00701-010-0777-4subject
Has Abstractpub_date
2010-12-01 00:00:00pages
2175-82issue
12eissn
0001-6268issn
0942-0940journal_volume
152pub_type
杂志文章abstract：BACKGROUND:Pre-/postoperative pituitary endocrine deficiencies in patients with sellar/parasellar non-adenomatous lesions are poorly described and studies have not considered the effect of sellar invasion on endocrine outcome. The aim of this study was to relate the need for pituitary hormone replacement pre-/postopera...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-020-04440-4
更新日期：2020-10-01 00:00:00
abstract：:Serpentine aneurysms of the posterior cerebral artery (PCA) treated by the internal maxillary artery (IMA) bypass are rare. Here, the authors report the case of a 34-year-old male patient who presented with a half-year history of gradual severe headache and right-sided limb monoparesis and paresthesia lasting for 1 we...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,评审
doi：10.1007/s00701-019-03902-8
更新日期：2019-06-01 00:00:00
abstract：:Behçet's disease is an unusual medical condition in central Europe and North America, however more common in Turkey and Japan. It was originally described in Turkey, characterized by recurrent oral ulcers, genital ulcers and also uveitis. A variety of vascular lesions such as venous occlusions, arterial aneurysms and ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-005-0516-4
更新日期：2005-05-01 00:00:00
abstract：BACKGROUND:Neuroprotective effects of recombinant human activated Protein C (rhAPC) in models of Spinal Cord Injury (SCI) and ischemic stroke have been reported in rodents. To rule out immunogenicity of rhAPC and to possibly maintain the physiological PC/thrombin balance the use of zymogen PC in SCI might be preferable...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-006-0784-7
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:The association between external ventricular drainage (EVD) and aneurysm rerupture is still a controversial issue. We performed a systematic review and meta-analysis of published series reporting data of EVD placement in aneurysmal subarachnoid hemorrhage (SAH) with the aim to evaluate the relationship betwe...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00701-017-3124-1
更新日期：2017-04-01 00:00:00
abstract：:The technical problems of surgery for anterior circle aneurysm have in large measure been solved. The problem of reduced perfusion to the brain which characterises the patient with aneurysmal subarachnoid haemorrhage in a poor clinical condition demands more subtle physiological handling. It appears likely that mainte...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01809133
更新日期：1978-01-01 00:00:00
abstract：BACKGROUND:Thoracic disc herniation (TDH) is a rare condition with severe neurological sequelae. Surgical management is still a matter of debate and challenging. METHOD:We present a modification of the transdural approach for TDH. The approach has been described in a stepwise fashion, analysing pre-, peri-, and postop...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-020-04387-6
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:The asymmetry of tonsillar ectopia, syringomyelia, and clinical manifestations, and their correlations in adult Chiari I malformation (CIM) are seldom discussed. METHODS:Clinical and imaging data of 104 consecutive adult patients with CIM and syringomyelia were retrospectively reviewed. A method was devised...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-014-2000-5
更新日期：2014-04-01 00:00:00
abstract：:Traditional clinical outcome measures for the treatment of Parkinson's disease (PD) have focused on motor function and activities of daily living. However, in the past decade there has been a new emphasis on the use of health related quality of life (HRQOL) measures for translating how a patient's response to treatmen...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s007010070090
更新日期：2000-01-01 00:00:00
abstract：:We describe multiparametric monitoring in severe head trauma using a new screwing device. Our aim was to create a screw which would make the implantation of the probes and thus multiparametric monitoring easier. The new screw allows us to implant 3 probes (microdialysis, Paratrend and an intracranial pressure device) ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s007010070077
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Lateral approaches to the brain stem for the resection of the cavernous malformations are preferred in order to avoid the structures within the floor of the fourth ventricle. The entry behind the pyramidal tract (PT) is usually carried out through the posterolateral surface of the brain stem. The more straig...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-011-1123-1
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Intraoperative navigated ultrasonography has reached clinical acceptance, while published data for the accuracy of some systems are missing. We technically quantified and optimised the accuracy of the integration of an external ultrasonography system into a BrainLab navigation system. METHODS:A high-end ult...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-017-3416-5
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Deep brain stimulation (DBS) is an effective treatment for essential tremor (ET). Currently the ventrolateral thalamus is the target of choice, but the posterior subthalamic area (PSA), including the caudal zona incerta (cZi), has demonstrated promising results, and the subthalamic nucleus (STN) has been sug...
journal_title：Acta neurochirurgica
pub_type： 临床试验,杂志文章
doi：10.1007/s00701-011-1157-4
更新日期：2011-12-01 00:00:00
abstract：:On the basis of a series of 75 patients, the practical use of Icp continuous long-term recording in severe head injuries without mass lesions or remaining deeply comatose after surgical procedures is critically analyzed. ICP monitoring alone seems to be not essential for prognosis. Conversely it is of much greater use...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01406729
更新日期：1977-01-01 00:00:00
abstract：:The diagnostic and prognostic values of quantitative isotope ventriculography (QIV), lumbar isotope cisternography (LIC), pneumoencephalography (PEG), and continuous intraventricular pressure recording (CIP) were assessed on the basis of the clinical course in 160 patients suspected of having acquired hydrocephalus. T...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01430586
更新日期：1979-01-01 00:00:00
abstract：BACKGROUND:According to recent findings, diffusion tensor tractography (DTT) only allows prediction of facial nerve location in relation to vestibular schwannoma (VS) with high probability. However, previous studies have not mentioned why only the facial nerve was selectively visualized. Our previous report investigate...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-015-2411-y
更新日期：2015-06-01 00:00:00
abstract：:In a period of 13 years 978 cases of severe head injuries were operated on in our clinic. An analysis of the medical reports includes injuries of the superficial dural sinus (39 cases = 4%): among these injuries of the anterior and central part of the superior sagittal sinus (66 per cent), injuries of the transverse s...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01541788
更新日期：1992-01-01 00:00:00
abstract：:Among 64 patients with hemifacial spasm (HFS) and 60 with trigeminal neuralgia (TN) treated by microvascular decompression (MVD), repeated MVD performed on 3 cases with HFS resulted in the absence of spasm in all cases. In 7 cases with TN, this technique resulted in complete remission in 2, recurrence in 3, and no pai...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01400583
更新日期：1992-01-01 00:00:00
abstract：:We present a patient with an intracerebral haematoma occurring at a remote site following evacuation of a chronic subdural haematoma. Recurrence of the haematoma, infection, seizure, cerebral edema, tension pneumocephalus and failure of the brain to expand due to cerebro-cranial disproportion are the major complicatio...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-008-1512-2
更新日期：2008-05-01 00:00:00
abstract：:Regional cerebral blood flow, recorded by the 133Xenon inhalation method, was measured preoperatively and over a five years postoperative period in six patients with completed stroke and stabilized neurological deficits, who had undergone omental transposition for revascularization of the ischaemic brain. Comparisons ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01809458
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:Nitric oxide is a key mediator of post-traumatic inflammation in the brain. We examined the expressions of iNOS, nNOS, and eNOS in inbred DA and PVGa rat strains where DA is susceptible to autoimmune neuroinflammation and PVGa-resistant. METHODS:Parietal contusions using a weight drop model were produced in...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-012-1297-1
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:The BrainIT group works collaboratively on developing standards for collection and analyses of data from brain-injured patients and to facilitate a more efficient infrastructure for assessing new health care technology with the primary objective of improving patient care. European Community (EC) funding supp...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,多中心研究
doi：10.1007/s00701-010-0719-1
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:Ventriculoatrial shunts were one of the most common treatments of hydrocephalus in pediatric and adult patients up to about 40 years ago. Thereafter, due to the widespread recognition of the severe cardiac and renal complications associated with ventriculoatrial shunts, they are almost exclusively implanted ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-020-04675-1
更新日期：2021-02-01 00:00:00
abstract：:MRI is routinely used in the evaluation and management of patients with failed back surgery syndrome (FBSS). However, its value is unclear in the early detection of signs that can negatively affect that later course of surgical cases. The purpose of the present study is to describe the MR images of early postoperative...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01844746
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Chronic subdural haematomas (cSDHs) have shown an increasing incidence in an ageing population over the last 20 years, while unacceptable recurrence rates of up to 30 % persist. The recurrence rate of cSDH seems to be related to the excessive neoangiogenesis in the parietal membrane, which is mediated via va...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00701-016-2949-3
更新日期：2016-11-01 00:00:00
abstract：:Ventricular shunting has dramatically improved the care of children with hydrocephalus. Yet shunt malfunctions are extremely common and cause significant morbidity. To document shunt problems in children with a neural tube defect and hydrocephalus, 67 children born since 1973 were studied via life-table analysis. 28% ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01418798
更新日期：1985-01-01 00:00:00
abstract：:Two cases of rupture of intracranial aneurysms and opacification of the lateral ventricles occurring during carotid angiography are reported and X-rays of the haemorrhage from the aneurysms are presented. Though the possibility of this complications remains a real one, the early use of this valuable procedure should n...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01406041
更新日期：1984-01-01 00:00:00
abstract：:The patient is a 44-year-old man who underwent resection of a posterior nasopharynx tumor 12 years earlier via left lateral rhinotomy approach. The final pathological analysis indicated the tumor was a craniopharyngioma, and the patient subsequently underwent focal radiation. The patient returned to medical attention ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-007-1168-3
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:The scientific activity of neurosurgeons and neurosurgery residents as measured by bibliometric parameters is of increased interest. While data about academic output for neurosurgeons in the USA, the UK, and Canada have been published, no similar results for German neurosurgical residents exist. Within this ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-019-04011-2
更新日期：2019-10-01 00:00:00
abstract：:The authors report a family in which two members had multiple intracranial aneurysms. This is the third reported family with more than one member affected by multiple cerebral aneurysms. The congenital nature and the patterns of inheritance of the disease are discussed. The indications for elective investigation of th...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01407233
更新日期：1981-01-01 00:00:00
