Abstract:
BACKGROUND:Pre-/postoperative pituitary endocrine deficiencies in patients with sellar/parasellar non-adenomatous lesions are poorly described and studies have not considered the effect of sellar invasion on endocrine outcome. The aim of this study was to relate the need for pituitary hormone replacement pre-/postoperatively, with sellar invasion, in non-adenomatous sellar/parasellar lesions. METHODS:Single-centre review of adults with histologically confirmed non-adenomatous sellar/parasellar lesion and follow-up ≥ 3 months or until postop radiotherapy. Pituitary dysfunction was defined by hormone replacement. The sellar encroachment score (0-6) was calculated as the sum of the thirds of radiological encroachment into the sellar region in the coronal and sagittal planes. Multivariate analysis with binary logistic regression was used to determine factors associated with pituitary hormone replacement. RESULTS:One hundred and seventeen patients were included with a median age of 49 years (range 16-84 years) and median follow-up of 13 months. Surgery was trans-sphenoidal (53%), trans-cranial (36%) or a combination (11%). The commonest histology types were meningioma (n = 33, 28%) and craniopharyngioma (n = 20, 17%). The median sellar encroachment score was 6 (range 0-6). Most (n = 86, 74%) did not require pituitary hormone replacement preoperatively. The need for pituitary hormones increased after surgery in 41 (35%) patients. In multivariate analysis, the sellar encroachment score was the only factor predictive of pre- (OR = 2.6, 95% CI = 1.2-5.5; p = 0.01) and postoperative risk of new pituitary hormone replacement (OR = 4.1, 95% CI = 1.7-10.1, p = 0.002). CONCLUSION:A significant proportion of these patients present with need for pituitary hormone replacement that may worsen postoperatively. The degree of sellar encroachment is predictive of pituitary hormone replacement status pre-/postoperatively.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Waqar M,Rampersad S,Bennett D,Kearney T,Gnanalingham KKdoi
10.1007/s00701-020-04440-4subject
Has Abstractpub_date
2020-10-01 00:00:00pages
2371-2379issue
10eissn
0001-6268issn
0942-0940pii
10.1007/s00701-020-04440-4journal_volume
162pub_type
杂志文章abstract::After clipping of intracranial aneurysms, postoperative vasospasm may occur remote from the distribution area of the artery and may cause death. The authors report two cases and give the clinical, neuroradiological, and neuroanatomical findings. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01773115
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Hydrocephalus may present with heterogeneous signs and symptoms. The indication for its treatment and the optimal drainage in complex cases may be challenging. Telemetric intracranial pressure measurements (TICPM) may open new perspectives for those circumstances. We report our experiences using the Neuroven...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-020-04421-7
更新日期:2020-10-01 00:00:00
abstract::In anaesthetized artificially ventilated dogs, the effect of graded arterial hypoxaemia on cerebral blood flow (CBF) and on the oxidative carbohydrate metabolism of the brain was tested. It is shown that the hypoxic vasodilatory influence on cerebral vessels is present even at moderate systemic hypoxaemia, provide tha...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01886665
更新日期:1976-01-01 00:00:00
abstract::It is critical that traumatic intracranial pseudoaneurysms should be removed completely from the parent artery because there is a possibility of significant morbidity and mortality from the high risk of rebleeding from any remnants of the pseudoaneurysm. However, the deconstruction of the parent artery has the risk of...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-011-1251-7
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION:Radiosurgery (RS) and fractionated radiotherapy (FRT) are part of the therapeutic armamentarium for the management of cavernous sinus meningiomas. We propose a systematic review of the local tumor control and clinical outcomes after monofractionated radiosurgical treatment, including gamma knife radiosurge...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,meta分析
doi:10.1007/s00701-018-3711-9
更新日期:2018-12-01 00:00:00
abstract::Four cases of primary intraosseous meningiomas were seen among 373 cases of intracranial meningiomas operated upon in the Neurosurgical Clinic of the Krankenhaus Nordstadt, Hannover, FRG between January 1978 and December 1988. These 4 cases represent 1% of all intracranial meningiomas. Patients' age ranged between 21 ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01402613
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:To analyse the intraoperative complications of a single neurosurgeon, with emphasis on devastating intraoperative incidents, and how they possibly could have been avoided. METHODS:All the patients operated upon by the author between 1986 and 2002, i.e. 252 patients with 270 craniotomies for 294 aneurysms, were...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-009-0452-9
更新日期:2009-09-01 00:00:00
abstract::The application of gallium-67 (67Ga) citrate has not been reported for the detection of an intracranial germinoma. The purpose of this report is to further evaluate the effectiveness of 67Ga scintigraphy in neurohypophyseal germinomas. 67Ga studies in five male patients with histologically verified intracranial pure g...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010070109
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Predicting the fate of patients who are given a misdiagnosis of aneurysmal subarachnoid hemorrhage (aSAH) remains unclear. The purpose was to examine factors associated with initial misdiagnosis of aSAH and to investigate the impact of initial misdiagnosis of aSAH on clinical outcomes. METHODS:Between Janua...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-018-3552-6
更新日期:2018-06-01 00:00:00
abstract::The feasibility of diagnosing the malignancy and viability of intraparenchymal brain tumours using Gd-DTPA, enhanced and unenhanced T1-weighted MRIs was investigated. The relationship between the Gd-DTPA enhancement pattern, the growth fraction (GF) determined by using the anti-bromide-oxyuridine (BrdU) monoclonal ant...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01400619
更新日期:1992-01-01 00:00:00
abstract::The authors report on four unusual cases of chronic adult hydrocephalus extracted from a large personal series of patients with hydrocephalic dementia. A syndrome resembling that of normal pressure hydrocephalus was due to the following aetiologies in these patients: Paget's disease of the skull, unruptured cerebral a...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01808923
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Multiple intracranial aneurysms (MIAs) are associated with poorer outcomes after rupture than are single intracranial aneurysms (SIAs). Although the risk factors for intracranial aneurysm rupture have been widely investigated, few studies have focused on MIAs. Thus, the present study aimed to determine wheth...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-2826-0
更新日期:2016-07-01 00:00:00
abstract::In this paper, we discuss the results of a study by light microscope of the effect of permanent clipping or ligation on the intracranial arteries of 38 operation dogs and 7 control dogs. The findings obtained are: 1. In the cerebral arterial circle, necrosis could easily result from ordinary clipping or ligation becau...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405851
更新日期:1982-01-01 00:00:00
abstract:INTRODUCTION:Advances in radiological imaging techniques have enabled volumetric measurements of meningiomas to be easily monitored using serial imaging scans. There is limited literature on the relationship between tumour growth rates and the WHO classification of meningiomas despite tumour growth being a major determ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3277-y
更新日期:2017-11-01 00:00:00
abstract::An investigation was carried out in 28 patients in order to evaluate the relationship between angiographically documented vasospasm, amount of subarachnoid blood found at surgery around ruptured intracranial aneurysms, and delayed ischaemic deficits. Angiography was performed at time intervals ranging between 5 and 17...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401750
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:Lateral orbitotomy can be minimalized using contemporary endoscopy. METHODS:Anatomy of the temporal fossa/orbital wall junction is described. The attachment of the temporal fascia is cut off from the orbital rim through a 1.5 cm skin incision in the lateral orbital wrinkle. The temporal muscle is detached f...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-014-2205-7
更新日期:2014-10-01 00:00:00
abstract::Arrested hydrocephalus probably results from improvement of CSF circulation during growth. Although a generally accepted condition, its mode of onset, its presence in a given patient, and time required to establish the absence of progressive hydrocephalus have not been defined. Five patients are presented with ostensi...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01809223
更新日期:1978-01-01 00:00:00
abstract:PURPOSE:This article provides a review of the transcriptomic expression profiling studies that have been performed on meningiomas so far. We discuss some future prospects and challenges ahead in the field of gene expression profiling. METHODS:We performed a systematic search in the PubMed and EMBASE databases in May 2...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-010-0906-0
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Although the majority of patients with minimal acute subdural hematomas (aSDHs) can be managed conservatively, some require delayed aSDH evacuation due to hematoma enlargement. This study was designed to determine the risk factors associated with delayed hematoma enlargement leading to surgery in patients wi...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-014-2151-4
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:The worldwide spread of smartphone usage enables new possibilities for longitudinal monitoring of objective functional impairment (OFI) in patients undergoing surgery for lumbar degenerative disc disease (DDD). METHODS:Three patients, undergoing elective surgery for lumbar DDD, self-assessed OFI using a rec...
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journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01420194
更新日期:1990-01-01 00:00:00
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journal_title:Acta neurochirurgica
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1991-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00701-015-2646-7
更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/BF01411428
更新日期:1995-01-01 00:00:00
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journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01406638
更新日期:1978-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00701-008-1502-4
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Surgery for gliomas is often confounded by difficulties in distinguishing tumor from surrounding normal brain. For better discrimination, intraoperative optical imaging methods using fluorescent dyes are currently being explored. Understandably, such methods require the demonstration of a high degree of diag...
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pub_type: 杂志文章
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更新日期:2019-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-09-01 00:00:00
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journal_title:Acta neurochirurgica
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Intraoperative fluorescence angiography with indocyanine green (ICG) as a tracer has recently been introduced as a novel technique for neurosurgery. We evaluated the feasibility and efficacy of near-infrared (NIR) indocyanine green (ICG) videoangiography for patients undergoing carotid endarterectomy (CEA). ...
journal_title:Acta neurochirurgica
pub_type: 临床试验,杂志文章
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更新日期:2011-08-01 00:00:00