Abstract:
BACKGROUND:Prevalence of patent foramen ovale (PFO) with detectable right-to-left shunt is higher in young adults with transient ischemic attack (TIA) and stroke compared to the general population. So far, published series included different occluder systems, various indications and regimens of postprocedural anticoagulation. In our experience, occluder systems may be associated with an increased prevalence of thrombus formation, which has also reported by other groups. The aim of the present study was to evaluate the follow-up results after implantation of the Amplatzer® occluder in patients with PFO using a consistent anticoagulation regimen. METHODS AND RESULTS:One-hundred and fourteen patients with PFO (60 men; age: 47 ± 13 years) and ≥1 thromboembolic event were included. Other causes for embolism were excluded. PFO-closure was successful in all patients. All patients were treated with aspirin (100 mg/day) and clopidogrel (75 mg/day) for 6 months. TEE was repeated at a mean of 10.3 months. Mean clinical follow-up period was 18 ± 9 months. After a mean of 10 months, no patient had either a significant residual shunt nor a suspected thrombus formation on the occluder. During follow-up, 5 patients suffered from neurological events (1 stroke, 2 TIAs, 2 epileptic seizures), though complete closure of the PFO was documented by TEE. One patient suffered from bleeding complications (upper GI-bleeding). CONCLUSION:Percutaneous closure of PFO in symptomatic patients by Amplatzer® occluder represents an effective therapy with a low incidence of peri-interventional complications and recurrent thromboembolism. Thrombus formations on the occluder system were not detected in this cohort.
journal_name
J Interv Cardioljournal_title
Journal of interventional cardiologyauthors
Fischer D,Haentjes J,Klein G,Schieffer B,Drexler H,Meyer GP,Schaefer Adoi
10.1111/j.1540-8183.2010.00593.xsubject
Has Abstractpub_date
2011-02-01 00:00:00pages
85-91issue
1eissn
0896-4327issn
1540-8183pii
JOIC593journal_volume
24pub_type
杂志文章abstract:UNLABELLED:The aim of this study was to determine the impact of previous with cytomegalovirus (CMV) on restenosis after aggressive angioplasty with provisional stenting. DESIGN:We prospectively studied 78 consecutive patients scheduled for 6-month follow-up coronary angiography as part of the SIPS study. Anti-CMV IgG ...
journal_title:Journal of interventional cardiology
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2002.tb01101.x
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abstract::Eighty-three consecutive patients with 85 coronary total occlusions undergoing coronary angioplasty were retrospectively studied. Patients were divided into two groups according to the occlusion age that was < 30 days (subacute total occlusion [STO]: 25 patients; range 1-30 days) or > 30 days (chronic total occlusion ...
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journal_title:Journal of interventional cardiology
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章,多中心研究
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章
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更新日期:2015-04-01 00:00:00
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journal_title:Journal of interventional cardiology
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章,多中心研究
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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更新日期:2012-02-01 00:00:00
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更新日期:2018-06-01 00:00:00
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journal_title:Journal of interventional cardiology
pub_type: 临床试验,杂志文章,多中心研究
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更新日期:1994-12-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,meta分析
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