Abstract:
BACKGROUND:The benefits of early abciximab administration and thrombus aspiration in ST elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) have previously been elaborated. However, whether there is an adjunctive effect of thrombus aspiration among STEMI patients, with angiographic evidence of thrombus, receiving early prehospital abciximab remains unclear. METHODS: In the context of a fixed protocol for PPCI, 158 consecutive patients with STEMI were enrolled, in whom abciximab was started early before hospital arrival (in-ambulance); 79 patients who had PPCI with thrombus aspiration (thrombectomy-facilitated PCI group), were compared to 79 who had PPCI without thrombus aspiration (conventional PCI group) in a prospective nonrandomized study. The primary end-point was complete ST-segment resolution within 90 minutes. Secondary end points included distal embolization, enzymatic infarct size as well as left ventricular ejection fraction (LVEF) assessed by gated single-photon emission computed tomography. Major adverse cardiac events (MACEs) were evaluated up to 12 months. RESULTS: Both groups were comparable for baseline characteristics. ST-segment resolution was significantly higher in the thrombectomy-facilitated group (P = 0.002), and multivariate analysis identified thrombectomy as an independent predictor of ST-segment resolution (OR = 9.4, 95% CI = 2.6-33.5, P = 0.001). Distal embolization was higher in the conventional PCI group among patients with higher thrombus grades. No difference was observed between both groups in infarct size assessed by peak creatine kinase (p = 0.689) and peak Tn-T levels (P = 0.435). Also, the LVEF at 3 months was similar (P = 0.957). At 12 month clinical follow-up, thrombus aspiration was, however, associated with reduced all-cause mortality (log-rank p = 0.032). CONCLUSION: Among STEMI patients treated with PPCI and in-ambulance abciximab, it appears that a selective strategy of thrombus aspiration still has additive benefit.
journal_name
J Interv Cardioljournal_title
Journal of interventional cardiologyauthors
Ahmed TA,Atary JZ,Wolterbeek R,Hasan-Ali H,Abdel-Kader SS,Schalij MJ,Jukema JWdoi
10.1111/j.1540-8183.2011.00686.xsubject
Has Abstractpub_date
2012-02-01 00:00:00pages
1-9issue
1eissn
0896-4327issn
1540-8183journal_volume
25pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVE:Drug-eluting stents have been shown to reduce the incidence of restenosis and target vessel revascularization (TVR) compared with bare metal stents (BMSs); however, the long-term efficacy of sirolimus-eluting stent (SES) implantation in patients with acute coronary syndrome (ACS) has not been w...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00446.x
更新日期:2009-06-01 00:00:00
abstract::The consistent message that emerges from virtually every recent acute coronary syndrome (ACS) trial is that the old "standard" of using aspirin and unfractionated heparin (UFH) can be considerably improved upon. Low molecular weight heparins (LMWHs) (most notably enoxaparin) are emerging as a broad replacement for UFH...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2002.tb01047.x
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the efficacy of sirolimus-eluting stents (SES) in the treatment of saphenous vein graft (SVG) disease. BACKGROUND:Percutaneous coronary intervention (PCI) of SVG lesions with bare metal stents (BMS) is associated with frequent in-stent restenosis, progression of dise...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2007.00301.x
更新日期:2007-12-01 00:00:00
abstract:AIMS:In severe myocardial dysfunction, extracorporeal life support (ECLS) can preserve organ perfusion. Occasionally, the high resulting afterload can lead to refractory pulmonary edema. We report our experience with percutaneous balloon atrioseptostomy used in this circumstance to discharge the left heart and prevent ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2011.00681.x
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:An anomalous origin of the right coronary artery (ARCA) from the left sinus of Valsalva (LSOV) has been reported in 6-27% of patients with coronary anomalies. The unusual location and course of this anomaly poses a technical challenge for the interventionalist. Appropriate guiding catheter selection is criti...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00463.x
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVES:Our aim was to investigate the risk of events related to non-culprit lesions after primary percutaneous coronary intervention (PCI) in patients with multivessel coronary disease (MVD). BACKGROUND:In patients undergoing primary PCI for ST-elevation myocardial infarction (STEMI) who are diagnosed with MVD, th...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1111/joic.12246
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:This study sought to identify patient and left atrial morphology specific factors associated with early complications for left atrial appendage occlusion with the Watchman™ (Boston Scientific, Natick, MA) device. BACKGROUND:Oral anticoagulation (OAC) is recommended for patients with atrial fibrillation, howe...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12374
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To compare the safety and efficacy of transcathether aortic valve-in-valve implantation (ViV-TAVI) in degenerated stentless bioprostheses with failed stented valves and degenerated native aortic valves. INTRODUCTION:Little is known about ViV-TAVI in degenerated stentless valves. METHODS:Out of 45 ViV-TAVI p...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12540
更新日期:2018-12-01 00:00:00
abstract::Chronic total occlusion (CTO) is a frequent finding in patients with coronary artery disease and when clinically indicated, remains one of the most challenging subsets for intervention. Although successful recanalization rates of CTO have remained suboptimal in percutaneous coronary intervention, evolving techniques i...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/joic.12268
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:Our aim was to establish the frequency of arterial anatomic variations and its relation to coronary procedural outcome in patients undergoing a first transradial coronary procedure. METHODS:This was a single center prospective study. A total of 1,446 consecutive patients undergoing their first transradial c...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2012.00693.x
更新日期:2012-08-01 00:00:00
abstract::We discuss the case of a 61-year-old male patient with hypertrophic cardiomyopathy and chest pain on exertion. Coronary angiography and intravascular ultrasound revealed an intermediate stenosis in the proximal site of the left anterior descending artery, while Tc-99m myocardial scintigraphy revealed exercise-induced ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2002.tb01029.x
更新日期:2002-02-01 00:00:00
abstract::Paravalvular leaks are a recognized complication of valve replacement surgery. We report a 47-year-old man with left atrial isomerism, interrupted left sided inferior caval vein with unilateral left sided superior caval vein, a common atrium, and anomalous pulmonary venous connection to the coronary sinus, who had rec...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2007.00290.x
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Drug-coated balloons (DCB) have been used to treat de novo small vessel coronary disease (SVD), with promising results and shorter dual antiplatelet therapy (DAPT) duration compared to drug-eluting stents (DES). We compared safety and effectiveness of the two treatments at 1 year. METHODS:We reviewed 3,613 ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12333
更新日期:2016-10-01 00:00:00
abstract:AIM:Over the past 2 decades, transcatheter occlusion of patent ductus arteriosus (PDA) with coils and the duct occluders evolved to be the procedure of choice. A new device, the Occlutech PDA® occluder (ODO) device has been designed. Herein, we aimed to evaluate the characteristics and short-term results of patients wh...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,多中心研究
doi:10.1111/joic.12290
更新日期:2016-06-01 00:00:00
abstract:AIMS:We sought to define the predictive value and evolution of N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels following transcutaneous aortic valve implantation (TAVI). METHODS AND RESULTS:We investigated 91 consecutive patients who underwent TAVI (59 transfemoral [TF], 32 transapical [TA]) in our instit...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2011.00654.x
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:The following retrospective observational study assesses the long-term results of intracoronary beta-radiation therapy for patients with in-stent restenosis. BACKGROUND:Beta-radiation has been used to treat patients with coronary in-stent restenosis. However, long-term clinical success using this technique h...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00522.x
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:To evaluate the effectiveness of the proximal optimization technique (POT) to prevent longitudinal stent elongation. BACKGROUND:The mechanism of stent elongation, which occurs after post-balloon dilation, is still unclear. METHODS:A total of 103 lesions treated with optical coherence tomography guided coro...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12543
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:To compare the effectiveness and safety of balloon aortic valvuloplasty (BAV) performed with or without rapid ventricular pacing (RP). BACKGROUND:BAV technique is poorly standardized. METHODS:One hundred consecutive patients were randomly assigned 1:1 between BAV performed with or without RP. Exclusion cri...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1111/joic.12452
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Paradoxical embolization from right-to-left shunt (RLS) resulting in neurological events is well described and patients with cryptogenic neurological disease are commonly evaluated for this condition. In the course of testing for RLS by bubble contrast transcranial Doppler (TCD), we observed that some patien...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00557.x
更新日期:2010-06-01 00:00:00
abstract::A recent observational study of coronary artery graft (CABG) versus drug-eluting stents (DES) performed in the state of New York reported that CABG was superior to DES for multivessel disease. Our comment provides rational criticism of this study, reviews the data that support a role for DES in the management of multi...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2008.00362.x
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Routine use of adjunctive devices to percutaneous coronary intervention (PCI) for the treatment of patients of ST-segment elevation myocardial infarction (STEMI) is questionable. Also, the clinical characteristics of STEMI patients that can modulate the treatment benefits of adjunctive devices are not fully ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,meta分析
doi:10.1111/j.1540-8183.2008.00420.x
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:The valve-in-valve (VIV) technique is an emerging therapeutic option for patients with failure of previously implanted xenografts. We describe a balloon-expandable transthoracic transapical mitral VIV implantation in an emergency setting in a 69-year-old woman with dysfunction of the mitral bioprosthesis. M...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2011.00637.x
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Ideally, percutaneous, mechanical closure of defects of the atrial septum should completely resolve shunt. To achieve this goal, more information is needed about the factors associated with device failure. METHODS:Consecutive patients with cryptogenic neurological events who had severe baseline Valsalva shu...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2011.00644.x
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Conventional two-dimensional angiography lacks the ability to properly image the true bifurcation geometry, and its percutaneous coronary intervention-induced changes in the clinical setting. METHODS AND RESULTS:A novel three-dimensional reconstruction system was investigated by retrospectively analyzing 39...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00512.x
更新日期:2010-02-01 00:00:00
abstract::Endovascular abdominal aortic aneurysm repair using a modular bifurcated stent-graft requires the initial placement of the main component in the infrarenal aorta, followed by insertion of additional iliac stent-graft(s) to exclude aneurysm and to securely affix the device. Placement of the contralateral iliac componen...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1034/j.1600-0854.2003.8046.x
更新日期:2003-06-01 00:00:00
abstract::Transradial coronary angiography (TRC) can be performed applying only one catheter fitting into the right and left coronary ostia (R/LCO). In this bicentric study (n = 2953), we analyzed the ostial performance of the Tiger_II_catheter widely used in TRC. Compared to Judkins catheters, the Tiger_II is frequently associ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12266
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Prevalence of patent foramen ovale (PFO) with detectable right-to-left shunt is higher in young adults with transient ischemic attack (TIA) and stroke compared to the general population. So far, published series included different occluder systems, various indications and regimens of postprocedural anticoagu...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00593.x
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:The transradial approach for coronary procedures is associated with a low complication rate, but specific training is considered mandatory. METHODS:Procedural characteristics (contrast dye: CD; fluoroscopy time: FT, patient radiation dose: RD) and local complication rates were prospectively assessed in 784 ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00603.x
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Optimal management of multivessel disease (MVD) in ST-segment elevation myocardial infarction (STEMI) patients treated by primary percutaneous coronary intervention (PCI) is still unclear. OBJECTIVES:To compare short- and long-term clinical outcomes of early-staged, angio-guided approach and delayed, ischem...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1540-8183.2011.00666.x
更新日期:2011-12-01 00:00:00
abstract::A significant proportion of patients with coronary artery disease have symptoms refractory to medical treatment, yet are unsuitable for conventional revascularization techniques, like percutaneous coronary intervention and coronary artery bypass surgery. Such patients are potential candidates for alternative forms of ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2002.tb01062.x
更新日期:2002-06-01 00:00:00