Serum selenium concentrations in rheumatoid arthritis.

abstract：INTRODUCTION:A recent genome-wide association study in European systemic sclerosis (SSc) patients identified three loci (PSORS1C1, TNIP1 and RHOB) as novel genetic risk factors for the disease. The aim of this study was to replicate the previously mentioned findings in a large multicentre independent SSc cohort of Cauc...

journal_title：Annals of the rheumatic diseases

authors： Bossini-Castillo L,Martin JE,Broen J,Simeon CP,Beretta L,Gorlova OY,Vonk MC,Ortego-Centeno N,Espinosa G,Carreira P,García de la Peña P,Oreiro N,Román-Ivorra JA,Castillo MJ,González-Gay MA,Sáez-Comet L,Castellví I,Schuer

更新日期：2013-04-01 00:00:00

abstract：:A novel, constitutively expressed and secreted interleukin 18 (IL18) binding protein (IL18BP) neutralises IL18. IL18BP shares many characteristics with soluble cytokine receptors of the IL1 family in that the protein exhibits specificity for IL18, belongs to the immunoglobulin-like class of receptors and has limited a...

journal_title：Annals of the rheumatic diseases

authors： Dinarello CA

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility of drug-free remission in patients with psoriatic arthritis (PsA) in continuous remission. METHODS:Prospective observational study in disease-modifying antirheumatic drug (DMARD)-treated PsA patients in continuous disease remission (no musculoskeletal symptoms, no or minimal sk...

journal_title：Annals of the rheumatic diseases

authors： Araujo EG,Finzel S,Englbrecht M,Schreiber DA,Faustini F,Hueber A,Nas K,Rech J,Schett G

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:Antiphospholipid antibody (aPL) specificity for aPL-related events was evaluated in systemic lupus erythematosus (SLE). METHODS:A study was carried out on 105 patients affected with SLE comparing the prevalence of lupus anticoagulant (LA) and IgG and IgM anticardiolipin antibodies (aCL) between patients with...

journal_title：Annals of the rheumatic diseases

authors： Ghirardello A,Doria A,Ruffatti A,Rigoli AM,Vesco P,Calligaro A,Gambari PF

更新日期：1994-02-01 00:00:00

abstract：:A 57 year old white man with aortic insufficiency and previously undiagnosed ankylosing spondylitis, who developed subacute bacterial endocarditis (SBE), is described. Emergency aortic valve replacement was necessary, and the aortic valve pathology showed diffusely fibrosed and thickened valve leaflets with bacterial ...

journal_title：Annals of the rheumatic diseases

authors： Hoppmann RA,Wise CM,Challa VR,Peacock JE

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVE:To study immunological markers and compare these markers with standard measures for the clinical and immunological follow up of vasculitis activity in hepatitis C virus (HCV) associated cryoglobulinaemic vasculitis (CV). METHODS:Serial serum samples from eight patients with newly diagnosed HCV associated CV ...

journal_title：Annals of the rheumatic diseases

authors： Lamprecht P,Moosig F,Gause A,Herlyn K,Csernok E,Hansen H,Gross WL

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:To determine whether the heterogeneous clinical response to tumour necrosis factor (TNF)alpha blocking therapy in rheumatoid arthritis (RA) can be predicted by TNFalpha expression in the synovium before initiation of treatment. METHODS:Prior to initiation of infliximab treatment, arthroscopic synovial tissue...

journal_title：Annals of the rheumatic diseases

authors： Wijbrandts CA,Dijkgraaf MG,Kraan MC,Vinkenoog M,Smeets TJ,Dinant H,Vos K,Lems WF,Wolbink GJ,Sijpkens D,Dijkmans BA,Tak PP

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To score systemic activity at diagnosis and correlate baseline activity with survival in a large cohort of patients with primary Sjögren syndrome (SS). PATIENTS AND METHODS:We include 1045 consecutive patients who fulfilled the 2002 classification criteria for primary SS. The clinical and immunological chara...

journal_title：Annals of the rheumatic diseases

authors： Brito-Zerón P,Kostov B,Solans R,Fraile G,Suárez-Cuervo C,Casanovas A,Rascón FJ,Qanneta R,Pérez-Alvarez R,Ripoll M,Akasbi M,Pinilla B,Bosch JA,Nava-Mateos J,Díaz-López B,Morera-Morales ML,Gheitasi H,Retamozo S,Ramos-Ca

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:To determine whether hormonal dysfunction involving the hypothalamic-pituitary-adrenal (HPA) axis, prolactin (PRL) secretion, and sex hormone status contribute to development of systemic lupus erythematosus (SLE). METHODS:11 patients with SLE and 9 healthy controls were tested for their total anterior pitui...

journal_title：Annals of the rheumatic diseases

authors： Köller MD,Templ E,Riedl M,Clodi M,Wagner O,Smolen JS,Luger A

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVES:To compare the prevalence and pattern of neuropsychiatric (NP) syndromes observed in systemic lupus erythematosus (SLE) to patients with Primary Sjögren syndrome (PSS) using the American College of Rheumatology (ACR) criteria for the 19 NP syndromes seen in SLE. METHODS:A population-based study was conducte...

journal_title：Annals of the rheumatic diseases

authors： Harboe E,Tjensvoll AB,Maroni S,Gøransson LG,Greve OJ,Beyer MK,Herigstad A,Kvaløy JT,Omdal R

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the presence of flow by Doppler ultrasound (DUS) in the wrist and finger joints (carpometacarpal 1 (CMC1), metacarpophalangeal (MCP), and proximal interphalangeal (PIP) joints) of healthy controls. METHODS:Twenty seven healthy volunteers (15 women, 12 men; mean age 45 years, range 18-93) with a t...

journal_title：Annals of the rheumatic diseases

authors： Terslev L,Torp-Pedersen S,Qvistgaard E,von der Recke P,Bliddal H

更新日期：2004-06-01 00:00:00

abstract：:Patients with Sjögren's syndrome alone (Ss), Sjögren's syndrome with rheumatoid arthritis (Ss-RA), and Sjögren's syndrome with Raynaud's phenomenon (Ss-RP) were typed for the HLA DR and MT antigens. Ss-RA patients had higher frequencies of HLA DR4 than did Ss patients. HLA-DR4 was also increased in frequency in patien...

journal_title：Annals of the rheumatic diseases

authors： Mann DL,Moutsopoulos HM

更新日期：1983-10-01 00:00:00

abstract：:While rheumatoid-factor-producing haemolytic plaque-forming cells (RF--PFC) of the human peripheral blood were easily inhibited by cycloheximide, mouse spleen cells immune to sheep red cells (anti-SRC PFC) were inhibited only after prolonged preincubation in the drug. The RF--PFC were easily inhibited by propranolol, ...

journal_title：Annals of the rheumatic diseases

authors： Moore TL,Rose JE,Vaughan JH

更新日期：1979-06-01 00:00:00

abstract：OBJECTIVES:While various monocyte chemokine systems are increased in expression in osteoarthritis (OA), the hierarchy of chemokines and chemokine receptors in mediating monocyte/macrophage recruitment to the OA joint remains poorly defined. Here, we investigated the relative contributions of the CCL2/CCR2 versus CCL5/C...

journal_title：Annals of the rheumatic diseases

authors： Raghu H,Lepus CM,Wang Q,Wong HH,Lingampalli N,Oliviero F,Punzi L,Giori NJ,Goodman SB,Chu CR,Sokolove JB,Robinson WH

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:To study the reliability and construct validity of ultrasound in interphalangeal finger joints affected by erosive osteoarthritis (EOA) and non-EOA with MRI as the reference method. METHODS:252 joints were examined by ultrasound, conventional radiography and clinical examination. Ultrasound was performed us...

journal_title：Annals of the rheumatic diseases

authors： Wittoek R,Jans L,Lambrecht V,Carron P,Verstraete K,Verbruggen G

更新日期：2011-02-01 00:00:00

abstract：:An explant method for the isolation of fibroblasts from adult human tendon is described. Cells were successfully isolated from 22 out of 27 common biceps tendons obtained from cadaveric donors (age range 11-83 years). The fibroblasts could be maintained in culture using standard methods and morphologically resembled t...

journal_title：Annals of the rheumatic diseases

authors： Chard MD,Wright JK,Hazleman BL

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:Sacroiliitis is a hallmark of the spondyloarthropathies (SpA). The degree of inflammation can be quantified by magnetic resonance imaging (MRI). The aim of this study was to further elucidate the pathogenesis of SpA by quantitative cellular analysis of immunostained sacroiliac biopsy specimens and to compare ...

journal_title：Annals of the rheumatic diseases

authors： Bollow M,Fischer T,Reisshauer H,Backhaus M,Sieper J,Hamm B,Braun J

更新日期：2000-02-01 00:00:00

abstract：:The serological diagnosis of juvenile rheumatoid arthritis (JRA) is difficult, with only 7-10% of patients 19S IgM rheumatoid factor positive. About 60-70% of patients are positive for hidden 19S IgM rheumatoid factor, but this test requires serum separation and is not available in most laboratories. Antiperinuclear f...

journal_title：Annals of the rheumatic diseases

authors： Nesher G,Moore TL,Grisanti MW,el-Najdawi E,Osborn TG

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is an urgent need for robust data on the trajectories and outcomes of pregnancies in women with inflammatory rheumatic diseases (IRD). In particular when rare outcomes or rare diseases are to be investigated, collaborative approaches are required. However, joint data analyses are often li...

journal_title：Annals of the rheumatic diseases

authors： Meissner Y,Fischer-Betz R,Andreoli L,Costedoat-Chalumeau N,De Cock D,Dolhain RJEM,Forger F,Goll D,Molto A,Nelson-Piercy C,Özdemir R,Raio L,Rodríguez-García SC,Sciascia S,Wallenius M,Zbinden A,Zink A,Strangfeld A

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The MEFV gene is responsible for familial Mediterranean fever (FMF). Several disease associated mutations have been identified. The range of genetic variation in MEFV in Greek patients has not been determined. OBJECTIVE:To describe a method that facilitates the routine screening of the entire coding sequenc...

journal_title：Annals of the rheumatic diseases

authors： Ritis K,Giaglis S,Spathari N,Micheli A,Zonios D,Tzoanopoulos D,Deltas CC,Rafail S,Mean R,Papadopoulos V,Tzioufas AG,Moutsopoulos HM,Kartalis G

更新日期：2004-04-01 00:00:00

abstract：:Fourteen patients with cystic fibrosis arthritis and eight patients with cystic fibrosis and hypertrophic osteoarthropathy were typed for HLA-A, B, C, DR, and DQ antigens and were compared with age and sex matched controls with cystic fibrosis. The diagnosis of cystic fibrosis arthritis and hypertrophic osteoarthropat...

journal_title：Annals of the rheumatic diseases

authors： Rush PJ,Gladman DD,Shore A,Anhorn KA

更新日期：1991-11-01 00:00:00

abstract：:Atlanto-axial subluxation occurs with a frequency varying from 6% to 45% in rheumatoid arthritis. Most patients are treated conservatively with a cervical collar. The effectiveness of different cervical collars in inhibiting anterior atlanto-axial subluxation was tested in 11 patients with classical rheumatoid arthrit...

journal_title：Annals of the rheumatic diseases

authors： Althoff B,Goldie IF

更新日期：1980-10-01 00:00:00

abstract：:The prosthetic knee joint of a 64 year old woman with severe rheumatoid arthritis was found to be infected with Listeria monocytogenes. After treatment with intravenous antibiotics, symptoms gradually resolved. She subsequently received prolonged treatment with oral co-trimoxazole and 18 months later remained well. ...

journal_title：Annals of the rheumatic diseases

authors： Booth LV,Walters MT,Tuck AC,Luqmani RA,Cawley MI

更新日期：1990-01-01 00:00:00

abstract：:A 62 year old woman taking L-tryptophan developed eosinophilic fasciitis shortly after starting an exercise class. She received prednisone without benefit but improved after azathioprine treatment was started and L-tryptophan was discontinued. As products containing L-tryptophan have recently been implicated in develo...

journal_title：Annals of the rheumatic diseases

authors： Hamilton ME

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:To characterise renal tissue metabolic pathway gene expression in different forms of glomerulonephritis. METHODS:Patients with nephrotic syndrome (NS), antineutrophil cytoplasmic antibody-associated vasculitis (AAV), systemic lupus erythematosus (SLE) and healthy living donors (LD) were studied. Clinically ...

journal_title：Annals of the rheumatic diseases

authors： Grayson PC,Eddy S,Taroni JN,Lightfoot YL,Mariani L,Parikh H,Lindenmeyer MT,Ju W,Greene CS,Godfrey B,Cohen CD,Krischer J,Kretzler M,Merkel PA,Vasculitis Clinical Research Consortium, the European Renal cDNA Bank cohort, and th

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to determine whether late apoptotic cell material directly induces autoantibodies characteristic of systemic lupus erythematosus (SLE) and to investigate the innate recognition pathways involved. METHODS:B6, B6.MyD88(-/-), B6.TLR7(-/-) and B6.TLR9(-/-) mice were subcutaneou...

journal_title：Annals of the rheumatic diseases

authors： Pan ZJ,Maier S,Schwarz K,Azbill J,Akira S,Uematsu S,Farris AD

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:The Psoriatic Arthritis Impact of Disease (PsAID) Questionnaire is a recently developed patient-reported outcome measure (PROM) of disease impact in psoriatic arthritis (PsA). We set out to assess the validity in an independent cohort of patients, estimate the minimally important difference for improvement a...

journal_title：Annals of the rheumatic diseases

authors： Holland R,Tillett W,Korendowych E,Cavill C,Waldron N,Brooke M,McHugh NJ

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:To determine whether rheumatoid factors (RFs), measured as continuous variables by time resolved fluoroimmunoassay, reflect disease activity in rheumatoid arthritis (RA). Further, to study the association of RFs and other disease activity parameters with radiological joint damage, especially in individual pa...

journal_title：Annals of the rheumatic diseases

authors： Knijff-Dutmer E,Drossaers-Bakker W,Verhoeven A,van der Sluijs Veer G,Boers M,van der Linden S,van de Laar M

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVES:Systemic immunological processes are profoundly shaped by the micro-environments where antigen recognition occurs. Identifying molecular signatures distinctive of such processes is pivotal to understand pathogenic immune responses and manipulate them for therapeutic purposes. Unfortunately, direct investigat...

journal_title：Annals of the rheumatic diseases

authors： Spreafico R,Rossetti M,van Loosdregt J,Wallace CA,Massa M,Magni-Manzoni S,Gattorno M,Martini A,Lovell DJ,Albani S

更新日期：2016-02-01 00:00:00

abstract：:In a search for aspects of behaviour related to oral contraceptive use which might explain the favourable effect of oral contraception on the onset of rheumatoid arthritis (RA), cigarette smoking and alcohol consumption were studied as possible risk factors. Information on cigarette smoking and alcohol consumption was...

journal_title：Annals of the rheumatic diseases

authors： Hazes JM,Dijkmans BA,Vandenbroucke JP,de Vries RR,Cats A

更新日期：1990-12-01 00:00:00