Improved endothelial function and reversal of myocardial perfusion defects after aerobic physical training in a patient with microvascular myocardial ischemia.

Abstract:

:The objective of this report is to document the effects of an aerobic training program on myocardial perfusion, and endothelial function abnormalities, and on the relief of angina in a patient with microvascular myocardial ischemia. A 53-year-old female patient exhibited precordial pain on effort and angiographically normal coronaries. Her symptoms had been present for 4 yrs despite pharmacologic treatment for the control of risk factors, with myocardial perfusion scintigraphy revealing an extensive reversible perfusion defect. She was submitted to aerobic training for 4 mos, obtaining significant improvement of the anginal symptoms. Additionally, after the aerobic training program, scintigraphy revealed the disappearance of the myocardial perfusion defect, with a marked improvement of endothelium-dependent vasodilatory response and an improved quality-of-life score. These results suggest that aerobic training can improve endothelial function, leading to a reduction of ischemia and an improved quality-of-life in patients with microvascular myocardial ischemia.

journal_name

Am J Phys Med Rehabil

authors

Carvalho EE,Crescêncio JC,Elias J Jr,Brito LB,Gallo L Jr,Simões MV

doi

10.1097/PHM.0b013e3181ddd6bb

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

59-64

issue

1

eissn

0894-9115

issn

1537-7385

journal_volume

90

pub_type

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