Serial electrodiagnostic studies in West Nile virus-associated acute flaccid paralysis.

Abstract:

:A man in his 70s presented for acute rehabilitation with severe acute flaccid asymmetric weakness in both lower limbs. Cerebrospinal fluid and serum immunoglobulin M titers were positive for West Nile virus. Electrodiagnostic studies demonstrated severe diffuse motor axonopathy consistent with an anterior myelitis. Electrodiagnostic and clinical improvements were monitored. Electrodiagnostic testing at 6 and 18 mos demonstrated continuing reinnervation; nascent voluntary motor unit action potentials were first noted proximally and, at 18 mos, distally in the left lower limb, including muscles in which motor unit potentials were not initially noted. Corresponding clinical improvements, though slow, were demonstrated even at 1(1/2) yrs after onset. Thus, motoric changes after West Nile virus-associated anterior myelitis need to be monitored over a prolonged time period to allow accurate assessment of prognosis for recovery in rehabilitation programs.

journal_name

Am J Phys Med Rehabil

authors

Marciniak C,Rosenfeld EL

doi

10.1097/01.phm.0000184160.87895.ea

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

904-10

issue

11

eissn

0894-9115

issn

1537-7385

pii

00002060-200511000-00012

journal_volume

84

pub_type

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