Abstract:
OBJECTIVE:The so-called bone-derived growth factor, beta2-microglobulin, has a regulatory function in bone metabolism by stimulating osteoclast activity. We undertook this study because osteoclast activity is known to be enhanced in patients with immobilized stroke, suggesting that their beta2-microglobulin concentrations may be increased. DESIGN:We studied 79 patients with acute stroke hemiplegia, including 36 men and 43 postmenopausal women ranging in age between 51 and 70 yr. RESULTS:The mean Barthel Index was 43 and 42 for men and women, respectively. The serum beta2-microglobulin concentration was increased in male and female patients, compared with the findings of 44 age-matched control subjects, and the serum concentration of pyridinoline cross-linked carboxyterminal telopeptide of type 1 collagen was also increased in male and female patients, compared with the findings of the control subjects. Serum concentrations of pyridinoline cross-linked carboxyterminal telopeptide of type 1 collagen correlated negatively with Barthel Index scores in both genders, indicating increased bone resorption caused by immobilization in these patients. Linear regression analysis revealed a positive correlation between beta2-microglobulin and pyridinoline cross-linked carboxyterminal telopeptide of type 1 collagen in both genders. CONCLUSIONS:These findings suggest that beta2-microglobulin reflects osteoclastic activity in response to stroke-induced immobilization in both genders. Beta2-microglobulin is a useful indicator of bone resorption in patients with immobilized stroke.
journal_name
Am J Phys Med Rehabiljournal_title
American journal of physical medicine & rehabilitationauthors
Sato Y,Kuno H,Kaji M,Tsuru T,Saruwatari N,Oizumi Kdoi
10.1097/00002060-200101000-00005subject
Has Abstractpub_date
2001-01-01 00:00:00pages
19-24issue
1eissn
0894-9115issn
1537-7385journal_volume
80pub_type
杂志文章,收录出版abstract:OBJECTIVE:Patients with endstage hip arthritis have poor ambulatory function. The aim of this study was to determine if perioperative exercise programs are well tolerated by these elderly patients and if a customized program can achieve an earlier recovery of normal ambulatory function after total hip arthroplasty. DE...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00002060-200211000-00001
更新日期:2002-11-01 00:00:00
abstract::The F-response is a valuable tool for evaluating the functional integrity of proximal nerve segments. Although many studies have focused on the various F-response characteristics observed (e.g., latency, amplitude, duration, persistence, etc.), few have examined the significance of stimulus parameters on the resultant...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199409000-00003
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVE:Upper limb spasticity may impair the use of control interfaces such as joysticks for many individuals with disabilities such as cerebral palsy (CP). The aims of this study were to compare the driving performance of those with CP to that of control participants, to identify the impact of lead time on performan...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e31825a1497
更新日期:2012-10-01 00:00:00
abstract::It has been suggested that the nerve fibers to the first and second lumbrical muscles are relatively spared in patients with carpal tunnel syndrome compared with the fibers to the abductor pollicis brevis. Latencies and amplitudes of the first lumbrical and the abductor pollicis brevis (APB) muscles were compared with...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199008000-00005
更新日期:1990-08-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to design patient-oriented risk models that elucidate the interactions among depressive symptoms, physical function, and sociodemographic markers and delineate the association of these indicators with 30-day readmissions. DESIGN:This prospective longitudinal study examined readmis...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000000213
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:This study aimed to explore to what extent the data collected for patients with low back pain, breast cancer, and stroke, based on the International Classification of Functioning, Disability and Health (ICF) Checklist, reflect the hypothesized single latent dimension functioning and whether the ICF qualifier ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,多中心研究
doi:10.1097/PHM.0b013e31823d53ff
更新日期:2012-02-01 00:00:00
abstract::This work summarizes our knowledge of the physiological basis of fatigue and the effects of exercise and pharmacological interventions on fatigue. Fatigue may be defined as physical and/or mental weariness resulting from exertion, that is, an inability to continue exercise at the same intensity with a resultant deteri...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,评审
doi:10.1097/phm.0b013e31802ba53c
更新日期:2007-01-01 00:00:00
abstract::Twenty-five men with spinal cord injuries were studied for evaluation of the hypothalamus-pituitary-adrenal axis, using corticotropin-releasing hormone and insulin-induced hypoglycemia. Twenty-five age-matched healthy male volunteers served as controls. Three spinal cord-injured subjects had hyperprolactinemia, three ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::Fatigue is the most commonly reported and most disabling of all post-polio sequelae (PPS). Bromocriptine mesylate (Parlodel) was employed in a placebo-controlled trial in five survivors of paralytic polio who continued to report moderate to severe daily fatigue after complying with the conservative treatments prescrib...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1097/00002060-199609000-00007
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVE:The current study was designed to document clinical and ultrasound (US) findings of patients with residual limb pain (RLP) after amputation and to investigate the relationship between these findings. MATERIALS AND METHODS:A chart review was performed to identify demographic and clinical data including the ag...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000000687
更新日期:2017-08-01 00:00:00
abstract::The ulnar antidromic sensory conduction study to the fifth digit is commonly performed in clinical electrodiagnosis. Several authors have published normal ranges for this study, but these published reports have been limited by generally small sample sizes. The purpose of this article is to present a large database of ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199911001-00012
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:The study analyzed the relationship between participation in the American Board of Physical Medicine and Rehabilitation maintenance of certification program and the incidence of disciplinary actions by state medical boards over a physician's career. The hypothesis is that physicians who do not maintain their ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001331
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:To compare the treatment effectiveness of botulinum toxin type A (BTX-A) and phenol blocks in managing lower limb spasticity and gait dysfunction in children with cerebral palsy. DESIGN:This is a case-controlled study that took place in a tertiary center's gait laboratory. A total of 27 ambulatory children w...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/01.phm.0000118038.02326.ca
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVE:Stroke is an acute neurologic dysfunction of vascular origin, characterized by loss of voluntary movement, sensory disturbances, and neurologic findings in the contralateral half of the body. Acute and long-term complications because of immobilization are seen in all organ systems. The aim of this study was t...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1097/00002060-200108000-00009
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine the correlations between objective performance-based physical function, self-reported physical function, quality of life, and gait function at 1 mo after unilateral total knee arthroplasty. DESIGN:Cross-sectional data from 195 patients who underwent unilateral primary t...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001222
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare pain induced by magnetic stimulation of the quadriceps femoris (QF) muscle with that induced by transcutaneous neuromuscular electrical stimulation (NMES). DESIGN:Magnetic stimulation and transcutaneous NMES were applied to QF muscles of 17 normal volunteers. The in...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1097/01.phm.0000223239.93539.fe
更新日期:2006-07-01 00:00:00
abstract::This study compared multidimensional and unidimensional measures of functional outcome from traumatic brain injury in a referred sample of 67 persons with moderate to severe traumatic brain injury who resided in the community or in a nonhospital facility. Four outcome indicators (independence in self-care, independenc...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199603000-00005
更新日期:1996-03-01 00:00:00
abstract::Complex regional pain syndrome has both nociceptive/inflammatory and neuropathic elements and is always (by definition) associated with abnormal activity of the sympathetic nervous system. There is good evidence that complex regional pain syndrome, as currently conceptualized, ultimately includes central sensitization...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:Motor Unit Number Index (MUNIX) is a quantitative electrophysiological measure that provides an index of the number of motor neurons supplying a muscle. The aim of this exploratory study is to assess the utility of MUNIX in the evaluation of patients with lumbar spinal stenosis (LSS). DESIGN:Participants wer...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001681
更新日期:2021-01-08 00:00:00
abstract::This study explores the "higher order" cognitive abilities of conceptual reasoning, problem solving, mental flexibility, and efficiency in 36 adolescents with spina bifida. The subjects, age 10 to 23 years, were assessed on a set of neuropsychological measures, and an individual profile analysis was conducted. All sub...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199805000-00011
更新日期:1998-05-01 00:00:00
abstract::Given the rarity of sural nerve mononeuropathy, this retrospective study reports 20 cases observed during the last 12 yr, with some cases having especially unusual mechanisms of the nerve lesion. Five of the 20 cases were considered S1 root disease until electrodiagnostic findings. In the 14 other cases, the nerve les...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-200211000-00014
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to assess the effects of elastic taping on pain, physical function, range of motion, and muscle strength in patients with knee osteoarthritis. DESIGN:We searched the PubMed, the Cochrane Central Register of Controlled Trials, Web of Science, Physiotherapy Evidence Database, Scopus, E...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,meta分析
doi:10.1097/PHM.0000000000001361
更新日期:2020-06-01 00:00:00
abstract::Abnormality of absolute values of median sensory conduction velocities and differences in conduction velocity between median and ulnar nerves are used as criteria for abnormality in the diagnosis of carpal tunnel syndrome. Detailed studies of sensory conduction in various median and ulnar branches and segments indicat...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-198910000-00002
更新日期:1989-10-01 00:00:00
abstract:OBJECTIVE:To investigate whether there is a difference in functional improvement in the affected arm of chronic stroke patients when comparing two methods of electrical stimulation. DESIGN:Explanatory trial in which 30 chronic stroke patients with impaired arm function were randomly allocated to either alternating ele...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/01.phm.0000133435.61610.55
更新日期:2004-08-01 00:00:00
abstract::Interest in global health is rising in graduate medical education. Trainees are increasingly seeking high quality, ethically sound, and educationally robust opportunities for global medical rotations. When based on best educational practices, these opportunities can provide a unique learning experience for residents i...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001652
更新日期:2020-11-26 00:00:00
abstract:OBJECTIVE:To evaluate health-related quality of life and disability in multiple-trauma patients requiring intensive care unit management. DESIGN:A total of 87 survivors of multiple trauma, with a median age of 31 yrs and a median Injury Severity Score of 22, were enrolled in the present study. The Nottingham Health Pr...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/01.phm.0000107497.77487.c1
更新日期:2004-03-01 00:00:00
abstract::Sarcoidosis is a multisystem granulomatous disorder that rarely involves the spinal cord. This report describes the presentation and rehabilitative course of a 31-yr-old man with quadriparesis secondary to spinal cord sarcoidosis. The patient had insidious, progressive weakness in his arms and legs for six weeks befor...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,评审
doi:10.1097/00002060-199104000-00002
更新日期:1991-04-01 00:00:00
abstract::In this study, we sought to assess the cardiopulmonary functions in three pediatric heart transplant recipients, two of whom are with dilated cardiomyopathy, whereas one is with cyanotic heart disease, in early postoperative period. Cardiopulmonary exercise testing was performed using an incremental cycling at 1 mo af...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e318238a0b1
更新日期:2012-02-01 00:00:00
abstract::Clinical practice guidelines (CPGs) provide an efficient route from research to practice because they follow a prescribed, vetted process for evidence collection. CPGs offer underserved fields, such as burn rehabilitation, an accessible approach to reliable treatment. A literature search was performed using the terms ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001442
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To determine the clinical usefulness of the compound nerve action potential of the common peroneal nerve recorded immediately distal to or at the fibular neck, at the same time stimulating the common peroneal nerve laterally at the posterior knee. DESIGN:For recording the compound nerve action potential of t...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-200102000-00006
更新日期:2001-02-01 00:00:00