Highly crosslinked polyethylene reduces wear in total hip arthroplasty at 5 years.

Abstract:

BACKGROUND:Although hip arthroplasty reliably relieves pain and improves function, problems have arisen with wear and osteolysis. Highly crosslinked polyethylene has been developed to address this problem although at present there is limited clinical evidence it does so longer term. QUESTIONS/PURPOSES:We compared the in vivo wear of standard versus highly crosslinked polyethylene (HXLP) in primary total hip arthroplasty at a minimum of 5-year followup. METHODS:We enrolled 122 patients in a prospective, double-blinded, randomized trial and followed them annually to assess their progress. Annual radiographs were analyzed using previously validated edge detection software to assess for two-dimensional, three-dimensional, and volumetric wear. The mean follow up was 5.5 years (range, 4.1 to 7 years). RESULTS:The two-dimensional wear measurements for HXLP showed lower wear compared to the conventional group (0.05 mm/year versus 0.26 mm/year, respectively). Three-dimensional and volumetric wear were similarly lower in the HXLP group. CONCLUSIONS:Highly crosslinked polyethylene undergoes substantially less wear than conventional polyethylene at medium term. The effect of hip arthroplasty longevity will need to be assessed with longer-term studies, but this may lead to a decreased need for revision as a result of less wear and osteolysis.

journal_name

Clin Orthop Relat Res

authors

Mutimer J,Devane PA,Adams K,Horne JG

doi

10.1007/s11999-010-1379-4

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

3228-33

issue

12

eissn

0009-921X

issn

1528-1132

journal_volume

468

pub_type

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