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Varicella Zoster antibodies among health care workers in a university hospital, Teheran, Iran.

Abstract：

OBJECTIVES:This study was designed to evaluate the immune status of health care workers against varicella zoster in a university hospital in Teheran, Iran, and to compare the history of chickenpox infection with the presence of varicella antibodies in this population. METHODS:Serologic testing for varicella was performed for 405 health care workers with different job categories and at different age. The enzyme immunoassay was used for determining IgG antibodies against varicella zoster virus. RESULTS:A total of 405 health care workers, aged 19-50 years (median: 29 years), were examined. Of these, 289 (71.4%) were found to be seropositive. No statistically significant differences were observed between gender, age, or occupation, and seropositivity (p = 0.09, 0.75, 0.54. respectively). Statistical analysis revealed that the correlation between chickenpox history and seropositivity showed a 62.3% sensitivity, 72.4% specificity, 84.9% positive predictive value, and 43.5% negative predictive value. CONCLUSIONS:Serologic screening of health care workers is essential to determine their immunity to varicella, regardless of the age, occupation and history of infection. This population is recommended to be considered a target group for future immunization programs in Iran.

journal_name

Int J Occup Med Environ Health

journal_title

International journal of occupational medicine and environmental health

authors

Talebi-Taher M,Noori M,Shamshiri AR,Barati M

doi

10.2478/v10001-010-0011-x

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

27-32

issue

1

eissn

1232-1087

issn

1896-494X

pii

72H026Q2LUV88162

journal_volume

23

pub_type

杂志文章

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