An analysis of HELLP syndrome cases: does platelet count predict adverse maternal and fetal outcomes in women with HELLP syndrome?

Abstract:

PURPOSE:To evaluate the maternal and fetal outcome in 44 pregnancies complicated with HELLP syndrome and to investigate the role of platelet counts in its prognosis. METHODS:A retrospective analysis of the medical records of 44 patients with the diagnosis of hemolysis elevated liver enzymes and low platelet count between June 1997 and January 2009 was performed. The patients were divided into two groups according to blood platelet count: platelet count <50,000 mm(3) formed Group I and platelet count 50,000-100,000 mm(3) formed Group II. Clinical findings and laboratory characteristics, maternal complications, perinatal outcomes and comparison of maternal and fetal morbidity according to platelet counts were analyzed. RESULTS:During the period of 12 years, 44 (0.54%) of 8,132 deliveries had HELLP syndrome. Among 44 patients, the most common complications were disseminated intravascular coagulopathy (18.2%), acute renal failure (15.9%), abruptio placentae (11.4%), and cerebral hemorrhage/infarction (11.4%). Maternal and perinatal mortality rates in HELLP syndrome were 9.1 and 40.9%, respectively. Aspartate aminotransferase levels were found to be statistically significantly higher in Group I (p = 0.04). While disseminated intravascular coagulopathy and acute renal failure were statistically significantly higher in Group I (p = 0.01; p = 0.03 respectively), fetal growth restriction was statistically significantly higher in Group II (p = 0.04). CONCLUSIONS:HELLP syndrome is associated with high incidences of maternal and fetal morbidity and mortality and patients with low platelet counts might have a much increased risk.

journal_name

Arch Gynecol Obstet

authors

Yucesoy G,Cakiroglu Y,Bodur H,Ozkan S,Tan T

doi

10.1007/s00404-010-1480-7

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

941-5

issue

5

eissn

0932-0067

issn

1432-0711

journal_volume

283

pub_type

杂志文章
  • The efficacy and toxicity of angiogenesis inhibitors for ovarian cancer: a meta-analysis of randomized controlled trials.

    abstract:PURPOSE:To evaluate the efficacy and toxicity of angiogenesis inhibitors for the treatment of ovarian cancer patients, we conducted a meta-analysis of the published literature on this subject. METHODS:In this meta-analysis, we searched PubMed, EMBASE, Web of Science, and Cochrane Library databases for randomized contr...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-020-05865-z

    authors: Guo C,Yan C,Qu L,Du R,Lin J

    更新日期:2020-11-21 00:00:00

  • Giant oocytes in human in vitro fertilization treatments.

    abstract:PURPOSE:Giant oocytes are potential sources of chromosomal abnormalities and should thus never be used in in vitro fertilization and embryo transfer (IVF-ET) procedures. The presence of giant oocytes may indicate the efficiency of the ovarian stimulation and can refer to the quality of sibling oocytes. METHODS:IVF cyc...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-015-3679-0

    authors: Lehner A,Kaszas Z,Murber A,Rigo J Jr,Urbancsek J,Fancsovits P

    更新日期:2015-09-01 00:00:00

  • [Immunologic assessment in habitual abortion].

    abstract::Since 1985, after excluding nonimmunological reasons for habitual abortion, we have been performing an MCL, a cross-match, and an HLA typing in these patients. Those with a low MLC response and a negative cross-match are considered to be immunological aborters. Only three out of 42 examined couples showed a low respon...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/BF02417221

    authors: Strowitzki T,Wiedemann R,Mempel W,Hepp H

    更新日期:1989-01-01 00:00:00

  • Successful pregnancy achieved by assisted reproductive techniques in a woman with severe congenital bicuspid aortic valve stenosis.

    abstract:OBJECTIVES:To report a twin pregnancy achieved by assisted reproductive techniques in a woman with severe congenital bicuspid aortic valve stenosis. METHODS:Intracytoplasmic sperm injection and embryo transfer was performed in a 38-year-old woman with a complaint of infertility for 8 years due to male factor and who p...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-006-0237-9

    authors: Erel CT,Erkan S,Simsek OY,Kucukoglu S

    更新日期:2007-04-01 00:00:00

  • Effect of bupivacaine-soaked spongostan in cesarean section wound on postoperative maternal health.

    abstract:PURPOSE:To investigate the efficacy of bupivacaine-soaked spongostan in cesarean section wound for postoperative anxiety level, satisfaction and early postpartum depression rate. METHODS:A total of 121 women, American Society of Anesthesiologists physical status I-II, scheduled to undergo general anesthesia and electi...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-014-3201-0

    authors: Simavli S,Kaygusuz I,Kafali H

    更新日期:2014-08-01 00:00:00

  • The relation between amniotic fluid surfactant concentration in preterm labour and histological evidence of chorioamnionitis.

    abstract::Concentration of amniotic fluid disaturated phosphatidylcholine (DSPC), factors related to cervical ripening, and histopathological evidence of chorioamnionitis were studied in 38 patients in preterm labour with intact membranes; all of them delivered spontaneously before 37 weeks. There was no correlation between the...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/BF02718276

    authors: Higuchi M,Hirano H,Gotoh K,Otomo K,Maki M

    更新日期:1992-01-01 00:00:00

  • Correlation between breast arterial calcification detected on mammography and cerebral artery disease.

    abstract:PURPOSE:This study was carried out to determine the relationship between breast arterial calcification (BAC) and cerebral artery disease. MATERIALS AND METHODS:We investigated the relationship between BAC on mammography and cerebral artery-origin T2-hyperintensity on brain MRI and which is associated with an increased...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-010-1742-4

    authors: Ahn KJ,Kim YJ,Cho HJ,Yim HW,Kang BJ,Kim SH,Kim HS,Kim KT,Lee JH,Whang IY

    更新日期:2011-10-01 00:00:00

  • Advanced first trimester screening (AFS): an improved test strategy for the individual risk assessment of fetal aneuploidies and malformations.

    abstract:OBJECTIVE:First trimester risk assessment for fetal aneuploidies is computed on the base of a general background risk, which is depending on the maternal age. Thereby, the adjusted risk tends to rise with increasing age. Obversely, more unsuspicious fetal parameters [measurement of the nuchal translucency (NT) and bioc...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-007-0324-6

    authors: Schmidt P,Rom J,Maul H,Vaske B,Hillemanns P,Scharf A

    更新日期:2007-08-01 00:00:00

  • Intrapartal pelvic floor protection: a pragmatic and interdisciplinary approach between obstetrics and urogynecology.

    abstract::Pelvic floor protection is an issue of increasing relevance. This article sought to summarize the session at last year's annual meeting of the German Society of Gynecology and Obstetrics (DGGG) in Stuttgart (10/2016) called "Urogynecology 2020-what is the optimal rate of cesarean section-does urogynecology have to dea...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-017-4316-x

    authors: Huebner M,Brucker SY,Tunn R,Naumann G,Reisenauer C,Abele H

    更新日期:2017-04-01 00:00:00

  • Correction to: Breast cancer patients' satisfaction with individual therapy goals and treatment in a standardized integrative medicine consultancy service.

    abstract::In the original version of this article contained an error in figure 1. It was provided in German. ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s00404-018-4785-6

    authors: Hack CC,Antoniadis S,Hackl J,Langemann H,Schwitulla J,Fasching PA,Beckmann MW,Theuser AK

    更新日期:2018-07-01 00:00:00

  • Appropriate interval between endometrial polyp resection and the proceeding IVF start.

    abstract:PURPOSE:Endometrial polyp is the commenest pathology among the structural uterine abnormalities. In this study we compared the IVF outcomes of patients who underwent hysteroscopic endometrial polyp excision with respect to the time interval between the polyp resection and the subsequent IVF cycle. MATERIALS AND METHOD...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-012-2238-1

    authors: Eryilmaz OG,Gulerman C,Sarikaya E,Yesilyurt H,Karsli F,Cicek N

    更新日期:2012-06-01 00:00:00

  • The effect of nasal oxytocin on pregnancy rates following intrauterine insemination: double-blind, randomized, clinical pilot study.

    abstract:PURPOSE:We tested the hypothesis that the application of intranasal oxytocin (8 IU) following intrauterine insemination (IUI) would increase pregnancy rates, without causing major side effects. METHODS:Randomized, double-blind, placebo-controlled pilot study: eighty-six couples with idiopathic infertility, polycystic ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-009-1284-9

    authors: Ochsenkühn R,Pavlik R,Hecht S,von Schönfeldt V,Rogenhofer N,Thaler CJ

    更新日期:2010-04-01 00:00:00

  • Spontaneous and indicated preterm delivery in pregestational diabetes mellitus: etiology and risk factors.

    abstract:OBJECTIVE:To characterize the indications for preterm delivery and identify risk factors predicting preterm delivery in pregnancies complicated by pregestational diabetes (PGDM). STUDY DESIGN:A retrospective cohort study of all women with type 1 or type 2 diabetes mellitus followed from preconception to delivery at ou...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-007-0541-z

    authors: Melamed N,Chen R,Soiberman U,Ben-Haroush A,Hod M,Yogev Y

    更新日期:2008-08-01 00:00:00

  • Color Doppler ultrasound (CDU) in the diagnosis of obstructive hydronephrosis in pregnant women.

    abstract:PURPOSE:Color Doppler ultrasound (CDU) accuracy of kidneys and bladder in the diagnosis and treatment of hydronephrosis and/or renal colic in pregnancies was evaluated. METHODS:Between January 2010 and September 2012, 234 pregnant women asymptomatic in 204 cases and with unilateral renal colic in 30 (median 26 years) ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-013-2768-1

    authors: Pepe F,Pepe P

    更新日期:2013-09-01 00:00:00

  • Polycystic ovaries: review of medical information on the internet for patients.

    abstract:BACKGROUND:Often, internet can bring a sense of anxiety rather than information and understanding to the patient. Our aim was to assess the quality of information available for patients on the management of polycystic ovarian syndrome (PCOS) on the internet. MATERIALS AND METHODS:Five search engines were searched usin...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-010-1378-4

    authors: Mallappa Saroja CS,Hanji Chandrashekar S

    更新日期:2010-05-01 00:00:00

  • The effects of peak and mid-luteal estradiol levels on in vitro fertilization outcome.

    abstract:PURPOSES:To evaluate the role of peak E2 level and its ratio to mid-luteal E2 level on implantation and clinical pregnancy rates in patients undergoing IVF cycles. METHODS:A retrospective study was designed covering 106 patients who were admitted to IVF Unit between June and October 2008. The patients were divided int...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-011-2090-8

    authors: Moraloğlu Ö,Tonguc EA,Özel M,Özakşit G,Var T,Sarikaya E

    更新日期:2012-03-01 00:00:00

  • Two- versus three-dimensional ultrasound in the second and third trimester of pregnancy: impact on recognition and maternal-fetal bonding. A prospective pilot study.

    abstract:OBJECTIVE:To assess the impact of three-dimensional (3D) versus two-dimensional (2D) ultrasound (US) on maternal-fetal bonding. STUDY DESIGN:Prospective randomized pilot study among low risk women with singleton fetuses in the second and third trimester. Dependent on the randomization pattern, US was commenced either ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-007-0368-7

    authors: Lapaire O,Alder J,Peukert R,Holzgreve W,Tercanli S

    更新日期:2007-11-01 00:00:00

  • New aspects in digital breast assessment: further refinement of a method for automated digital anthropometry.

    abstract:PURPOSE:In this trial, we used a previously developed prototype software to assess aesthetic results after reconstructive surgery for congenital breast asymmetry using automated anthropometry. To prove the consensus between the manual and automatic digital measurements, we evaluated the software by comparing the manual...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-020-05862-2

    authors: Hartmann R,Weiherer M,Schiltz D,Baringer M,Noisser V,Hösl V,Eigenberger A,Seitz S,Palm C,Prantl L,Brébant V

    更新日期:2020-11-12 00:00:00

  • Maternal anthropometric measurements as predictors of low birth weight in developing and developed countries.

    abstract:PURPOSE:To evaluate the possibility of using maternal anthropometric measurements for prediction of low birth weight in developing and developed countries. METHODS:Bivariate diagnostic meta-analysis was performed with hierarchical summary receiver operating characteristic curves. Ten databases, i.e., PubMed, EMBASE, C...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,meta分析

    doi:10.1007/s00404-015-3721-2

    authors: Goto E

    更新日期:2015-10-01 00:00:00

  • Randomized comparison of total laparoscopic, laparoscopically assisted vaginal and vaginal hysterectomies for myomatous uteri.

    abstract:PURPOSE:To compare the operative data and early postoperative outcomes of total laparoscopic hysterectomy (TLH), laparoscopically assisted vaginal hysterectomy (LAVH) and vaginal hysterectomy (VH). METHODS:One hundred and eight women requiring hysterectomy for enlarged myomatous uterus were randomly allocated into thr...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-014-3228-2

    authors: Sesti F,Cosi V,Calonzi F,Ruggeri V,Pietropolli A,Di Francesco L,Piccione E

    更新日期:2014-09-01 00:00:00

  • Large angioleiomyoma, rich of mast cell and sex hormone receptor expression.

    abstract:BACKGROUND:Angioleiomyoma is a rare benign solitary tumor, arising from the vascular smooth muscle. This tumor usually occurs in the subcutis of extremities, uncommonly in abdomen, often presents as a small (<2 cm) and is treated with excision. CASE:We report an extremely rare case of unusually large angioleiomyoma, f...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-008-0663-y

    authors: Hayashi M,Tomita S,Fukasawa I,Inaba N

    更新日期:2009-02-01 00:00:00

  • Sperm exposure during menses is a risk factor for developing antisperm antibody (ASA) in female.

    abstract:PURPOSE:Intercourse during menses is a sexual behavior practiced by 3-30 % of sexually active women. Defense responses of mucosal immunity in the female genital tract regulated by sex hormones would be impaired during menses. The present study seeks to clarify whether unprotected sexual activity during menses will incr...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-013-2883-z

    authors: Wang YX,Zhu WJ,Jiang H

    更新日期:2013-11-01 00:00:00

  • Live birth after laparotomy for concurrent heterotopic pregnancy and appendicitis in a 6 weeks IVF pregnancy.

    abstract:BACKGROUND:A term delivery after concurrent appendectomy and salpingectomy at 6 weeks in an appendicitis coexisting with a heterotopic pregnancy after in vitro fertilization (IVF) treatment is reported. METHODS:Case report. RESULTS:The patient presented with severe low abdominal pain at 6 weeks of pregnancy after IVF...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-006-0254-8

    authors: Daponte A,Spyridakis M,Ioannou M,Vanakara P,Tzovaras G,Hatzitheofilou K,Messinis IE

    更新日期:2007-05-01 00:00:00

  • Human papillomavirus DNA, HPV L1 capsid protein and p16INK4a protein as markers to predict cervical lesion progression.

    abstract:OBJECTIVES:Cervical cancer is the most common malignant tumors in women leading to serious morbidity and mortality worldwide, especially among developing countries. A main cause of the disease is the high-risk human papillomavirus (HR-HPV) infection. HSIL usually progress to cervical cancer, and low-grade lesions, incl...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-018-4931-1

    authors: Hu H,Zhao J,Yu W,Zhao J,Wang Z,Jin L,Yu Y,Han L,Wang L,Zhu H,Li F

    更新日期:2019-01-01 00:00:00

  • Does tumor grade influence the rate of lymph node metastasis in apparent early stage ovarian cancer?

    abstract:PURPOSE:To evaluate the prevalence of regional lymph node (LN) metastasis in patients with non-clear cell epithelial ovarian cancer apparently confined to the ovary, stratified by tumor grade. METHODS:The National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database was accessed (1988-2014). ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-018-4789-2

    authors: Nasioudis D,Mastroyannis SA,Ko EM,Latif NA

    更新日期:2018-07-01 00:00:00

  • Pregnancy outcomes in patients with Alport syndrome.

    abstract:PURPOSE:To analyze the maternal and obstetric outcomes of patients with Alport syndrome. METHODS:We describe the pregnancy course of 8 pregnancies of three family members with the autosomal dominant (the rarest) form of Alport syndrome. We also analyzed 10 previously reported pregnancies with other Alport mutations in...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-015-3893-9

    authors: Yefet E,Tovbin D,Nachum Z

    更新日期:2016-04-01 00:00:00

  • An effect of maternal nifedipine therapy on fetoplacental blood flow: a prospective study.

    abstract:PURPOSE:The aim of this study is to assess the effects of maternal nifedipine administration on placental and fetal blood flow. METHODS:A total of 29 patients with preterm labor diagnosis admitted to the tertiary care center, Zeynep Kamil Hospital, were evaluated. Before and 24-48 h after administration of oral nifedi...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-018-4839-9

    authors: Namazov A,Grin L,Karakus R,Uludogan M,Ayvaci H

    更新日期:2018-10-01 00:00:00

  • The impact of cigarette smoking and alcohol consumption on sperm parameters and sperm DNA fragmentation (SDF) measured by Halosperm(®).

    abstract:PURPOSE:Both cigarette smoking and alcohol consumption are somehow implicated in sperm function, but the impact of these two lifestyle factors on sperm parameters remains controversial. The present study is focused on the impact of cigarette smoking and alcohol consumption separately and combined on sperm parameters an...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-014-3281-x

    authors: Anifandis G,Bounartzi T,Messini CI,Dafopoulos K,Sotiriou S,Messinis IE

    更新日期:2014-10-01 00:00:00

  • Accuracy of sonographic fetal weight estimation: influence of the scan-to-delivery interval in combination with the applied weight estimation formula.

    abstract:INTRODUCTION:To evaluate the influence of the time interval between examination and delivery on the accuracy of sonographic fetal weight estimation (WE). MATERIALS AND METHODS:8723 singleton pregnancies were included in this retrospective cohort study. Fetuses were divided into eight groups with regard to the time int...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-015-3989-2

    authors: Faschingbauer F,Raabe E,Heimrich J,Faschingbauer C,Schmid M,Mayr A,Schild RL,Beckmann MW,Kehl S

    更新日期:2016-09-01 00:00:00

  • Development and psychometric evaluation of the Sexual Health Assessment Tool for Infertile Women (SEHAT-IW).

    abstract:PURPOSE:This study aimed to develop a valid and reliable tool for evaluation of sexual health assessment in infertile women. METHODS:This was a mixed exploratory study consisting of two phases. At phase one, we reviewed the existing instruments and interviewed 20 infertile women to generate an item pool. Then, the res...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-020-05832-8

    authors: Daneshfar Z,Sadatmahalleh SJ,Kazemnejad A,Ahmadi F

    更新日期:2020-10-19 00:00:00