Growth of vascularized composite mandibular allografts in young rabbits.

Abstract:

:Forty-one hemimandible allografts were transplanted in young rabbits immunosuppressed with cyclosporine. The majority of the grafts demonstrated normal wound healing, and growth of hair, bone, and teeth. The mandibular body and the premolars showed significant growth in length. The allografted mandibles functioned sufficiently that the rabbits took oral nourishment soon after surgery. Long-term survival was limited by a toxic "wasting syndrome" specific for rabbits under treatment with cyclosporine.

journal_name

Ann Plast Surg

authors

Randzio J,Kniha H,Gold ME,Chang TT,Su LD,Park HH,Cho JS,Booth K,Furnas DW

doi

10.1097/00000637-199102000-00006

subject

Has Abstract

pub_date

1991-02-01 00:00:00

pages

140-8

issue

2

eissn

0148-7043

issn

1536-3708

journal_volume

26

pub_type

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