Abstract:
BACKGROUND:There is no consensus with regard to antibiotic prophylaxis usage in clean and clean-contaminated plastic and reconstructive surgery. This meta-analysis sought to assess the efficacy and safety of antibiotic prophylaxis and to determine appropriate duration of prophylaxis. METHODS:An English language literature search was conducted using PubMed and the Cochrane Collaboration for randomized controlled trials (RCTs) that evaluate the use of antibiotic prophylaxis to prevent postoperative surgical site infection (SSI) in patients undergoing clean and clean-contaminated plastic and reconstructive surgery. Data from intention-to-treat analyses were used where available. For the dichotomous data, results for each study were odds ratio (OR) with 95% confidence interval (CI) and combined for meta-analysis using the Mantel-Haenszel method or the DerSimonian and Laird method. Study quality was critically appraised by 2 reviewers using established criteria. STATA version 12 was used for meta-analyses. RESULTS:Twelve RCTs involving 2395 patients were included, of which 8 trials were considered to be of high methodological quality. Effect of antibiotic prophylaxis in plastic and reconstructive surgery was found favorable over placebo in SSI prevention (13 studies; 2449 participants; OR, 0.53; 95% CI, 0.4-0.7; P < 0.01) and the other wound complication (OWC) prevention (9 studies; 1843 participants; OR, 0.36; 95% CI, 0.15-0.84; P < 0.02). Subgroup analysis performed according to surgical wound type or the duration of prophylaxis did not modify the results except for the OWC with short-term antibiotic treatment. Compared with short-term antibiotic prophylaxis, long-term administration showed no evidence of a difference in risk of SSI (7 studies; 1012 participants; OR, 0.99; 95% CI, 0.63-1.55; P < 0.95), OWC (5 studies; 824 participants; OR, 0.92; 95% CI, 0.46-1.86; P < 0.82), and adverse event relative to antibiotic administration (3 studies; 653 participants; OR, 0.23; 95% CI, 0.01-4.92; P < 0.35). CONCLUSIONS:This meta-analysis of RCTs provides evidence supporting that antibiotic prophylaxis reduced postoperative SSI in clean plastic surgeries with high-risk factors and clean-contaminated plastic surgeries. Besides, a short-course administration regimen seemed to be of adequate efficacy and safety. High-quality prospective trials on larger scale are needed to further confirm these findings.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Zhang Y,Dong J,Qiao Y,He J,Wang T,Ma Sdoi
10.1097/01.SAP.0000440955.93769.8csubject
Has Abstractpub_date
2014-01-01 00:00:00pages
121-30issue
1eissn
0148-7043issn
1536-3708pii
00000637-201401000-00028journal_volume
72pub_type
杂志文章,meta分析,评审abstract::Correction of major saddle nose deformities is one of the greatest challenges in nasal surgery. Here, a new approach for the correction of major saddle nose deformities in which the missing parts of the nasal skeleton are replaced with their anatomic replicas sculptured from an autogenous osteocartilagineous rib graft...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181586069
更新日期:2008-08-01 00:00:00
abstract::Diagnosing osteomyelitis in patients with pressure ulcers is complicated by overlying soft-tissue inflammation and reactive bone formation. We set out to evaluate the efficacy of indium scanning in the diagnosis of chronic osteomyelitis in spinal-cord-injury patients with grade IV pressure ulcers. The goal was to esti...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000164467.97551.ed
更新日期:2005-06-01 00:00:00
abstract::Incomplete unilateral cleft lips show a wide range of deformities, ranging from microform to near-complete clefts. Because there are different amounts and qualities of tissue present on the cleft and non-cleft sides, surgical approaches should make distinctions based on the remnant tissue. A new procedure using an upp...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318295dceb
更新日期:2015-03-01 00:00:00
abstract::The aim of the present study was to evaluate in young animals the dynamics of calvarial bone healing when exposing a bone defect to continuous forces for up to 13 weeks. Six-week-old rabbits after a sagittal suture strip craniectomy were randomized for either of the following protocols: (1) no spring was applied (n = ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000229019.29857.14
更新日期:2006-11-01 00:00:00
abstract::Long-term reviews of patients undergoing augmentation mammaplasty seem to be rare. Recently, a long-term study of patients who had undergone augmentation with polyurethane foam-covered prostheses was undertaken. However, at the time that study was published, the longest follow-up was just over 4 years. We have been us...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199107000-00004
更新日期:1991-07-01 00:00:00
abstract:PURPOSE:Limb salvage in bone sarcomas requires resection and joint and soft-tissue reconstruction. Suboptimal coverage can lead to prosthesis infection, subsequent hardware exposure, or loss with eventual amputation. In the pediatric sarcoma population, it is essential to not only have viable soft-tissue coverage but o...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3182223d5b
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to explore the feasibility and early effect of digital design combined with 3-dimensional (3D) printing technique in the transplantation of vascular pedicled iliac bone flap in the treatment of avascular necrosis of the femoral head. METHODS:The navigation template was designed accor...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002362
更新日期:2020-05-01 00:00:00
abstract::Burn wound sepsis can be due to exogenous or endogenous bacteria. When rare organisms cause infection, exogenous sources are implicated. This sets into motion hospital infection control team searches, which are both exhausting and harassing to patients and staff. This study examines the skin bacteria present at admiss...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198907000-00007
更新日期:1989-07-01 00:00:00
abstract::A 69-year-old woman with a history of mastectomy and radiotherapy for breast carcinoma demonstrated extensive anterior thoracic wall radionecrosis 22 years later. The latissimus dorsi musculocutaneous flap was chosen to repair two distant ulcerative defects. Chest wall coverage was performed by dividing the muscle int...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199410000-00011
更新日期:1994-10-01 00:00:00
abstract::The authors report a case of an epidermal inclusion cyst found in the deep infratemporal fossa 12 years after the patient sustained blunt trauma to that region. Posttraumatic epidermal inclusion cysts are rare and occur mainly in the fingers, palms, and soles. Introduction of the epidermal elements into the dermis dur...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200101000-00015
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Dynamic Infrared Imaging (DIRI) is a noninvasive technique that precisely analyzes the infrared radiation of any object. We used this technique to locate the dominant perforator vessels in flap surgery in conjunction with conventional Doppler. METHODS:Ten patients scheduled for deep inferior epigastric arte...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181ef6da3
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Concerns of nonlasting results and potential nasal growth damage precluded cleft nasal correction at the time of initial cleft lip repair. Our goal was to evaluate the outcome of primary cleft nasal correction in our patients with unilateral cleft lip. METHODS:A retrospective review of patients with complet...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002039
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The infraorbital region is a unique facial subunit surrounded with several important structures, such as the lower eyelids, oral commissure, ala nasi, and the sideburns. The potential for distortion of these neighboring anatomic landmarks and the absence of natural creases where incisional scars can be camou...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31820d6830
更新日期:2011-12-01 00:00:00
abstract::A more direct measurement of implant capsule contracture is needed for the laboratory study of this phenomenon. Most of the previous methods for quantitation of contracture rely on measurements of deformability. Because contraction of an implant capsule is in fact a decrease in the surface area of the capsule, a metho...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198311000-00008
更新日期:1983-11-01 00:00:00
abstract::Three cases of hereditary lateral cervical fistulas are reported. The patients had lateral cervical fistulas bilaterally and different types of auricular malformations. The mothers of the patients also had lateral cervical fistulas. Moreover, one mother had bilateral microtias and the other mothers bilateral preauricu...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198805000-00009
更新日期:1988-05-01 00:00:00
abstract::Treating pigmented lesions of the skin, especially deep dermal pigmentations, are difficult to achieve satisfactory results without complications. To treat dermal pigmentations, such as nevus of Ota and congenital nevus, the combined therapy of a resurfacing laser (CO2) and a selective photothermolytic laser (the Q-Sw...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200107000-00006
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Current trends in the management of medial orbital wall fractures are toward the development of transconjunctival incisions and the use of endoscopic-assisted methods. Different authors have suggested variations of the medial transconjunctival approach. METHODS:(1) In 30 fresh cadaver orbits, the classic tr...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000531
更新日期:2016-03-01 00:00:00
abstract::A case of multiple symmetric lipomatosis in a 61-year-old man is described. The patient had the striking appearance that characterizes multiple symmetric lipomatosis. He had a history of alcohol abuse. Before admission to our institution, he underwent surgical treatment three times at other hospitals. We describe his ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-198911000-00015
更新日期:1989-11-01 00:00:00
abstract::Five patients, ages 2 to 5 years, were successfully treated for cervical lymphadenitis caused by the avium intercellulari complex of atypical bacteria. Preoperative treatment with standard antituberculosis therapy had been unsuccessful. Extensive surgery requiring a conservative radical neck dissection was sometimes r...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:
更新日期:1981-09-01 00:00:00
abstract:BACKGROUND:High-quality physician communication is the foundation for achieving high patient satisfaction. Increasing importance is placed on eliciting feedback from patients. However, there have been few studies looking at the impact of resident involvement on patient satisfaction. Our hospital system values the patie...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001339
更新日期:2018-05-01 00:00:00
abstract::After 30 years of clinical use, the 1992 Food and Drug Administration moratorium on silicone gel breast implants (SGBIs) resulted from a paucity of scientific data concerning their safety. The frequency of rupture and reoperative procedures was not known, nor were reliable data available for changes in the physical pr...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,meta分析
doi:10.1097/00000637-200209000-00001
更新日期:2002-09-01 00:00:00
abstract::A new procedure for repairing damage to the scrotum caused by Fournier's gangrene is dscribed. Complete and quick covering of the exposed testicles is important aesthetically and functionally. A distally based flap split in the middle is designed. Flap viability is ensured by an abundant blood supply and venous return...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198205000-00009
更新日期:1982-05-01 00:00:00
abstract:PURPOSE:The cholinergic anti-inflammatory pathway may play an important role in early burn edema. Therefore, we evaluated the influence of cdp-choline on early systemic burn edema and leukocyte activation in shock in rat mesenteries after burn plasma transfer. METHODS:Burn plasma harvested from donor rats 4 hours afte...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000605
更新日期:2015-10-01 00:00:00
abstract::Medical research has a long history of joint venture between commercial entities and nonindustry researchers. Significant concern exists among accrediting bodies for medical education and federal granting agencies that conflicts of interest (COIs) exist that affect the validity of the research. This study evaluates th...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000672
更新日期:2016-06-01 00:00:00
abstract::Fourteen patients with erythematous and/or hypertrophic scars resulting from remote surgical excision or trauma were evaluated and subsequently treated with one to two flashlamp-pumped pulsed dye (585 nm) laser treatments over a 2-month period. Clinical assessments were performed before commencement and at the end of ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199402000-00015
更新日期:1994-02-01 00:00:00
abstract::Gynecomastia is an abnormal enlargement of the breast tissue in men. It is the most common disorder of the male breast. Surgical sharp resection of the excess breast tissue is still the mainstay of treatment when medical treatment modalities are proved to be ineffective. The authors believe that areolar incisions give...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000143513.77819.7a
更新日期:2005-02-01 00:00:00
abstract::Coronary artery bypass grafting is a common surgical procedure for myocardial revascularization. This operation usually involves the use of the left internal mammary artery to bypass the left anterior descending coronary artery. The internal mammary artery and its perforators are also an important blood supply to the ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000141597.38288.3c
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Patients with unilateral cleft lip and palate (CLP) deformities commonly develop nasal airway obstruction, necessitating septoplasty at the time of definitive rhinoplasty. We assessed the contribution of the bony septum to airway obstruction using computed tomography (CT) and cone beam CT (CBCT). METHODS:A ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000027
更新日期:2015-07-01 00:00:00
abstract::The repair of intractable ulcer over the Achilles' tendon in a patient with Werner's syndrome is described. The ulcer was covered successfully with a lateral supramalleolar flap combined with a delay procedure. Partial necrosis of the flap occurred; however, the necrotic area could be repaired with a skin graft becaus...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199809000-00015
更新日期:1998-09-01 00:00:00
abstract:UNLABELLED:Periprosthetic infections of oncologic reconstructions have an amputation rate between 37% and 87%. Eleven patients with an infected knee reconstruction following limb salvage surgery for cancer were treated with the staged protocol. All patients underwent prosthetic removal and implantation of an antibiotic...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000203990.08414.ad
更新日期:2006-05-01 00:00:00