Abstract:
:The risk of venous thromboembolism (VTE) in patients with cancer is 6-12-fold higher than in the general population, and VTE is the second leading cause of death in this population, after cancer itself. The etiology underlying the increased risk of VTE is multifactorial and complex, involving patient-, tumor-, and treatment-related factors. In patients with cancer, cumulative results from studies in those with VTE versus without VTE suggest that anticoagulation therapy, particularly with low-molecular-weight heparins, prevents morbidity and may reduce mortality. Despite the availability of effective and safe therapeutic options, VTE is often underrecognized and suboptimally managed. Interventions such as assessing individual patient risk of VTE, providing VTE prophylaxis and/or prompt treatment, and adopting VTE guidelines are essential aspects of cancer-related care. Aggressive VTE management and strategies are critical to improving survival in patients with cancer and VTE.
journal_name
Pharmacotherapyjournal_title
Pharmacotherapyauthors
Saraiya B,Goodin Sdoi
10.1592/phco.29.11.1344subject
Has Abstractpub_date
2009-11-01 00:00:00pages
1344-56issue
11eissn
0277-0008issn
1875-9114pii
10.1592/phco.29.11.1344journal_volume
29pub_type
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