Cryosectioning of hair follicles. An improved method using liquid nitrogen conduction freezing.

abstract：:Interleukin-17A inhibitors are a promising alternative to tumor necrosis factor-α inhibitors for the treatment of psoriasis. In-class switch has been hardly investigated for interleukin-17A inhibitors. We report the experience (2017-2018) of a tertiary medical center with interleukin-17A-inhibitor switch in patients w...

journal_title：Acta dermato-venereologica

authors： Sherman S,Solomon Cohen E,Amitay-Laish I,Hodak E,Pavlovsky L

更新日期：2019-07-01 00:00:00

abstract：:Treatment of symptomatic oral lichen planus remains a challenging problem. This study compared the efficacy of topical tacrolimus ointment with triamcinolone acetonide ointment in patients with oral lichen planus. Twenty patients (group I) were treated with topical tacrolimus 0.1% ointment 4 times daily, and 20 (group...

journal_title：Acta dermato-venereologica

authors： Laeijendecker R,Tank B,Dekker SK,Neumann HA

更新日期：2006-01-01 00:00:00

abstract：:Retinol and proguanil are metabolised by the same family of hepatic cytochrome P450, i.e. CYP2C. We used proguanil as a probe to study CYP2C activity, and by implication retinol metabolism, in psoriasis. In vitro studies showed that retinol competitively inhibited the hepatic metabolism of proguanil to cycloguanil. Pr...

journal_title：Acta dermato-venereologica

authors： Helsby NA,Ward SA,Parslew RA,Friedmann PS,Rhodes LE

更新日期：1998-03-01 00:00:00

abstract：:Irritation and staining, the side effects of dithranol and related compounds have previously been studied after a single chamber-exposure. To mimic the therapeutic situation, the chamber application was repeated for 3 weeks on the uninvolved back skin of 17 psoriasis patients. In equimolar concentrations corresponding...

journal_title：Acta dermato-venereologica

authors： Brandt H,Mustakallio KK

更新日期：1983-01-01 00:00:00

abstract：:The effect of topical indomethacin on the weal and flare response was measured in 9 patients with chronic dermographic urticaria. An augmentation of dermographic wealing by topical indomethacin was shown with lowering of the weal threshold from 22.3 +/- 4.7 g/mm2 (mean +/- SEM, n = 9) to 16.4 +/- 3.8 (p < 0.005), but ...

journal_title：Acta dermato-venereologica

authors： Sharpe GR,Shuster S

更新日期：1993-02-01 00:00:00

abstract：:Autosomal dominant and recessive forms of dystrophic epidermolysis bullosa (DEB) result from mutations in the type VII collagen gene (COL7A1). Although paradigms have emerged for genotype/phenotype correlation in DEB, some pathogenic mutations in COL7A1, notably glycine substitutions within the type VII collagen tripl...

journal_title：Acta dermato-venereologica

authors： Almaani N,Liu L,Dopping-Hepenstal PJ,Lai-Cheong JE,Wong A,Nanda A,Moss C,Martinéz AE,Mellerio JE,McGrath JA

更新日期：2011-05-01 00:00:00

abstract：:Data regarding the efficacy and safety of methotrexate (MTX) in adults with localized scleroderma (LoS) is scarce. This study gathered data from a retrospective cohort of adult patients with LoS (n?=?107), treated with MTX (1993-2015). MTX drug survival and predictors thereof were analysed. After 1 and 2 years, 26% an...

journal_title：Acta dermato-venereologica

authors： Mertens JS,van den Reek JM,Kievit W,van de Kerkhof PC,Thurlings RM,Radstake TR,Seyger MM,de Jong EM

更新日期：2016-11-02 00:00:00

abstract：:Fourteen patients with monosymptomatic delusions of infestation were followed-up 19-48 months after treatment with pimozide was terminated. Seven patients had remained in remission since the treatment. Three had developed relapses, but were without symptoms with intermittent treatment. Four patients responded poorly t...

journal_title：Acta dermato-venereologica

authors： Lindskov R,Baadsgaard O

更新日期：1985-01-01 00:00:00

abstract：:5-S-Cysteinyldopa (5-S-CD), a pheomelanin precursor, has been used as a biochemical marker of melanoma metastasis. Recently, 5-hydroxy-6-methoxyindole-2-carboxylic acid (5H6MI2C), a eumelanin-related metabolite, was shown to reflect well the degree of skin pigmentation. We measured the urinary excretion of 5H6MI2C and...

journal_title：Acta dermato-venereologica

authors： Wakamatsu K,Ito S,Fujita K

更新日期：1988-01-01 00:00:00

abstract：:In 94% of the patients with dermatitis herpetiformis, a locally applied ointment with an ester of nicotinic acid (Trafuril) induced an abnormal reaction with erythema, edema, papules, and often vesicles. The appearance of the reaction to Trafuril is similar to DH lesions. It differs markedly from the reactions to iodi...

journal_title：Acta dermato-venereologica

authors： Michaëlsson G,Svensson L

更新日期：1975-01-01 00:00:00

abstract：:Aryl hydrocarbon hydroxylase (AHH) and glutathione S-transferase (GST) (EC 2.5.1.18) activity were measured in human lymphocytes of peripheral blood from 8 patients with irritant or allergic contact dermatitis of the hands, and compared with data from a control group. Both AHH and GST activity was found to be signific...

journal_title：Acta dermato-venereologica

authors： Singh N,Hamann K,Clausen J

更新日期：1982-01-01 00:00:00

abstract：:Assessment of the effectiveness of teledermatology has been hampered by the variety of outcome measures used, limiting the possibility for meta-analysis. This systematic mapping review classified the outcome measurement instruments used in randomized controlled trials of teledermatology conducted between 2008 and 2018...

journal_title：Acta dermato-venereologica

authors： Chow A,Soon C,Smith HE,Apfelbacher CJ

更新日期：2019-12-01 00:00:00

abstract：:A 73-year-old woman with rheumatoid arthritis was treated with Levamisole, 150 mg per day, on 2 days a week. Her arthritis improved, but she developed a severely itching rash, and the treatment was stopped after 6 months. Penicillamine was subsequently given and tolerated without skin complications. 15 months after re...

journal_title：Acta dermato-venereologica

authors： Secher L,Permin H,Skov PS,Ullman S,Halberg P

更新日期：1978-01-01 00:00:00

abstract：:Many patients with moderate-to-severe plaque psoriasis do not respond adequately to methotrexate monotherapy. This pilot study, with a small patient population, was performed to evaluate the effectiveness and safety of etanercept and methotrexate combination in patients with plaque psoriasis and inadequate response to...

journal_title：Acta dermato-venereologica

authors： Zachariae C,Mørk NJ,Reunala T,Lorentzen H,Falk E,Karvonen SL,Johannesson A,Claréus B,Skov L,Mørk G,Walker S,Qvitzau S

更新日期：2008-01-01 00:00:00

abstract：:Systemic contact dermatitis may occur in contact-sensitized individuals when they are exposed to haptens orally, transcutaneously, intravenously or by inhalation. We report the case of a woman developing a diffuse skin eruption after the topical use of Rhus toxicodendron alcoholic extract and the oral introduction of ...

journal_title：Acta dermato-venereologica

authors： Cardinali C,Francalanci S,Giomi B,Caproni M,Sertoli A,Fabbri P

更新日期：2004-01-01 00:00:00

abstract：:In patients with atopic dermatitis the skin is highly susceptible to infection by bacteria, fungi and viruses. Increasing knowledge about the complex immune network that regulates anti-microbial responses has helped to dissect further the role of infections in atopic dermatitis. Conserved patterns of microbes are reco...

journal_title：Acta dermato-venereologica

authors： Biedermann T

更新日期：2006-01-01 00:00:00

abstract：:It is well known that the genital skin may be affected by psoriasis. However, little is known about the prevalence and clinical appearance of genital psoriasis, and genital skin is often neglected in the treatment of psoriatic patients. We performed an extensive systematic literature search for evidence-based data on ...

journal_title：Acta dermato-venereologica

authors： Meeuwis KA,de Hullu JA,Massuger LF,van de Kerkhof PC,van Rossum MM

更新日期：2011-01-01 00:00:00

abstract：:There has been no previous systematic study of bullous skin diseases with granular basement membrane zone deposition exclusively of C3. In this study we collected 20 such patients, none of whom showed cutaneous vasculitis histopathologically. Oral dapsone and topical steroids were effective. Various serological tests ...

journal_title：Acta dermato-venereologica

authors： Hashimoto T,Tsuruta D,Yasukochi A,Imanishi H,Sekine H,Fujita T,Wanibuchi H,Gi M,Kárpáti S,Sitaru C,Zone JJ,Endo D,Abe S,Nishino T,Koji T,Ishii N

更新日期：2016-08-23 00:00:00

abstract：:Given the long purported anecdotal association between rosacea and gastrointestinal disease, the discovery that Helicobacter pylori causes gastritis and duodenal ulcer disease has led to a hypothesized role for this organism in the aetiology of rosacea. We conducted a case-series study of 49 patients to assess the pot...

journal_title：Acta dermato-venereologica

authors： Diaz C,O'Callaghan CJ,Khan A,Ilchyshyn A

更新日期：2003-01-01 00:00:00

abstract：:Three women with hyperkeratosis lenticularis perstans (HLP) are described. The lesions developed after the age of 45 and there was no family history of this disease. The possible role of UV-light in the pathogenesis of this disease is discussed. ...

journal_title：Acta dermato-venereologica

authors： Rosdahl I,Rosén K

更新日期：1985-01-01 00:00:00

abstract：:While temperatures in the noxious range are well-known to inhibit acute itch, the impact of temperature in the innocuous temperature range is less well understood. We investigated the effect of alternating short-term temperature changes in the innocuous range on histamine and cowhage-induced acute itch, taking into ac...

journal_title：Acta dermato-venereologica

authors： Lewis Z,George DN,Cowdell F,Holle H

更新日期：2019-02-01 00:00:00

abstract：:Vulvar vestibulitis, as defined by Friedrich, is considered to be inflammatory, despite the fact that the normal histology of this specific area has previously not been characterized. The aim of the present study was to compare the normal histology of the vulvar vestibulum with findings in localized vulvar vestibuliti...

journal_title：Acta dermato-venereologica

authors： Lundqvist EN,Hofer PA,Olofsson JI,Sjöberg I

更新日期：1997-07-01 00:00:00

abstract：:Infection can be a trigger and an aggravating factor in psoriasis. Antibacterial and/or antifungal agents are commonly used in the treatment of intertriginous psoriasis, because it is believed that flexures in psoriasis are often colonized by Candida species and Staphylococcus aureus. Bacterial and fungal cultures wer...

journal_title：Acta dermato-venereologica

authors： Flytström I,Bergbrant IM,Bråred J,Brandberg LL

更新日期：2003-01-01 00:00:00

abstract：:Hypopigmented macules are frequently observed in the photodamaged skin of elderly people. We undertook to study and treat 2 types of hypomelanosis of photoaged skin. These lesions were: 1) idiopathic guttate hypomelanosis; and 2) macular hypomelanosis. Comparative studies included: 1) high-resolution photography using...

journal_title：Acta dermato-venereologica

authors： Pagnoni A,Kligman AM,Sadiq I,Stoudemayer T

更新日期：1999-07-01 00:00:00

abstract：:Apoptosis is a form of cellular suicide and is activated in various cells, including keratinocytes, in response to physiological and pathological stimuli. A current hypothesis holds that apoptotic cells in a concerted manner express characteristic phenotypic features comprising cytoplasmic budding, pyknosis, chromatin...

journal_title：Acta dermato-venereologica

authors： Gniadecki R,Gajkowska B,Bartosik J,Hansen M,Wulf HC

更新日期：1998-07-01 00:00:00

abstract：:Experience gained from cooperation between dermatologists and vascular surgeons in 177 patients evaluated at a joint leg ulcer clinic is reported. Patients were divided into two subgroups: (i) 86 patients with healed ulcers and (ii) 91 patients with ongoing therapy-resistant ulcers. Venous insufficiency was the most c...

journal_title：Acta dermato-venereologica

authors： Bjellerup M,Akesson H

更新日期：2002-01-01 00:00:00

abstract：:To assess the role of epidermal melanin in a patient with porphyria variegata and vitiligo, the MED was determined in pigmented and vitiliginous skin for wavelengths of 310, 405 and 500 nm. The energy required to elicit erythema by irradiating vitiliginous skin at 310 nm was half that for pigmented skin. For 405 nm th...

journal_title：Acta dermato-venereologica

authors： Westerhof W,Bebelaar D,Cormane RH,Langelaar J,Hup JM

更新日期：1981-01-01 00:00:00

abstract：:Patients with suspected cutaneous adverse drug reactions are often referred to allergy clinics or departments of dermatology for evaluation. These patients are selected compared with patients identified in prospective and cross-sectional studies of hospital populations. This explains the observed variation in prevalen...

journal_title：Acta dermato-venereologica

authors： Borch JE,Andersen KE,Bindslev-Jensen C

更新日期：2006-01-01 00:00:00

abstract：:While localized variants of granuloma annulare are typically self-limited, disseminated granuloma annulare tends to be chronic and often therapy-resistant. Treatment with fumaric acid esters is effective for severe forms of psoriasis. Disseminated granuloma annulare has also been reported to respond to fumaric acid es...

journal_title：Acta dermato-venereologica

authors： Weber HO,Borelli C,Röcken M,Schaller M

更新日期：2009-01-01 00:00:00

abstract：:A double-blind randomized controlled trial with a paired split-scar design compared verapamil, an L-type Ca2+ channel antagonist, and triamcinolone for prevention of keloid recurrence after excision. Ca2+ channel blocking activity of verapamil in keloid cells was explored. One keloid was excised per subject and each w...

journal_title：Acta dermato-venereologica

authors： Danielsen PL,Rea SM,Wood FM,Fear MW,Viola HM,Hool LC,Gankande TU,Alghamdi M,Stevenson AW,Manzur M,Wallace HJ

更新日期：2016-08-23 00:00:00