Potential of Ginkgo biloba L. leaves in the management of hyperglycemia and hypertension using in vitro models.

Abstract:

:Leaves from four different Ginkgo biloba L. trees (1 and 2--females; 3 and 4--males), grown at the same conditions, were collected during a period of 5 months (from June to October, 2007). Water and 12% ethanol extracts were analyzed for total phenolics content, antioxidant activity, phenolic profile, and the potential in vitro inhibitory effects on alpha-amylase, alpha-glucosidase, and Angiotensin I-Converting Enzyme (ACE) enzymes related to the management of diabetes and hypertension. The results indicated a significant difference among the trees in all functional benefits evaluated in the leaf extracts and also found important seasonal variation related to the same functional parameters. In general, the aqueous extracts had higher total phenolic content than the ethanolic extracts. Also, no correlation was found between total phenolics and antioxidant activity. In relation to the ACE inhibition, only ethanolic extracts had inhibitory activity.

journal_name

Bioresour Technol

journal_title

Bioresource technology

authors

Pinto Mda S,Kwon YI,Apostolidis E,Lajolo FM,Genovese MI,Shetty K

doi

10.1016/j.biortech.2009.07.021

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

6599-609

issue

24

eissn

0960-8524

issn

1873-2976

pii

S0960-8524(09)00890-6

journal_volume

100

pub_type

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