Abstract:
:In 2004, Cambodia, a low-income country, undertook a rapid scale-up of free antiretroviral therapy (ART) through the public sector in order to respond to the need for treatment for those living with HIV/AIDS. A cohort of patients initiating ART in a provincial national hospital was set up at the beginning of the program to monitor the impact of treatment on patients. Patients provided information on behaviors through face-to-face interviews. Medical data were obtained from clinical files. Health-related quality of life (HRQOL) was assessed using the Medical Outcomes Study 21-Items Short Form (MOS SF-21). Patients were interviewed when initiating ART and followed up at 3 months, 6 months, and each consecutive 6 months thereafter. From March 2005 through January 2008, the cohort included 549 patients followed for a total of 645 person-years. The 4.0% of patients lost to follow-up were considered dead in the analysis. Incidence of mortality was 9.1 per 100 person-years, which is comparable to international standards. HRQOL subscale scores increased dramatically in the first year after initiating ART. The mean of overall HRQOL score rose from 63.0 at baseline to 81.1 at 1 year and 89.9 at 30 months of follow-up (chi(2) for trends p < 0.001). Simultaneously, the proportion of patients with full-time employment increased from 48.8% to 95.7%.We conclude that the rapid scaling-up of ART delivery in a resource poor Asian setting dramatically improved the survival and well-being of its beneficiaries, who in turn resumed productive lives within their communities.
journal_name
AIDS Patient Care STDSjournal_title
AIDS patient care and STDsauthors
Morineau G,Vun MC,Barennes H,Wolf RC,Song N,Prybylski D,Chawalit Ndoi
10.1089/apc.2008.0241subject
Has Abstractpub_date
2009-08-01 00:00:00pages
669-77issue
8eissn
1087-2914issn
1557-7449journal_volume
23pub_type
杂志文章abstract::Despite successful implementation of anonymous voluntary human immunodeficiency virus (HIV) counseling and testing (aVCT) in Taiwan, the trend of late HIV presentation in sexually active populations has remained unchanged in Taiwan over the past decade. We evaluated the effect and acceptance of an aVCT cascade program...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
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journal_title:AIDS patient care and STDs
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journal_title:AIDS patient care and STDs
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章
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journal_title:AIDS patient care and STDs
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journal_title:AIDS patient care and STDs
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journal_title:AIDS patient care and STDs
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2005.19.429
更新日期:2005-07-01 00:00:00
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pub_type: 杂志文章
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章
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journal_title:AIDS patient care and STDs
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2012.0406
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pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
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journal_title:AIDS patient care and STDs
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
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journal_title:AIDS patient care and STDs
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journal_title:AIDS patient care and STDs
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journal_title:AIDS patient care and STDs
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