Minimal withdrawal of dual antiplatelet agents under the guidance of a point-of-care platelet activity assay early after drug-eluting stent implantation for surgical removal of renal cell carcinoma.


:A 58-year-old man presented with unstable angina, for whom drug-eluting stent (DES) was successfully implanted in mid portion of left anterior descending artery and diagonal branch bifurcation. During hospitalization, renal cell carcinoma was incidentally found. Right radical nephrectomy was planned 5 weeks after the DES insertion to minimize thrombotic risk following discontinuation of antiplatelet agents. Seven days and 5 days prior to the operation, clopidogrel and aspirin were withdrawn respectively while platelet activity was serially monitored using VerifyNow Aspirin/P2Y12 assay. According to the results of the assay, the infusion of tirofiban was started from the third day after stopping dual antiplatelet therapy and maintained till 8 h prior to the nephrectomy. With the help of this bridge therapy, the surgery was successfully performed and histology confirmed a renal cell carcinoma. Clopidogrel and aspirin were resumed the next day after the operation. Eight days after his nephrectomy, the patient was discharged without stent thrombosis or bleeding complication.


Int J Cardiol


Park SJ,Oh IY,Kim KH,Shin DH,Yang HM,Lee HY,Koo BK




Has Abstract


2011-06-02 00:00:00














  • Sulpiride induced torsade de pointes.

    abstract::Antipsychotic agents are known to be associated with a long QT interval and torsade de pointes. We report a 69 year old female who suffered from a syncopal attack at a psychiatric hospital and was referred to our center. Torsade de pointes with a long QT interval (QTc=680 ms) was observed on the 12 lead ECG in the eme...

    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Huang BH,Hsia CP,Chen CY

    更新日期:2007-06-12 00:00:00

  • Relation of the SAMe-TT2R2 score to quality of anticoagulation control and thromboembolic events in atrial fibrillation patients: Observations from the SPORTIF trials.

    abstract:BACKGROUND:Oral anticoagulant therapy is central to the prevention thromboembolic events in atrial fibrillation (AF) patients. The SAMe-TT2R2 score is a simple clinical-derived score designed to aid decision-making on whether or not a patient is likely to achieve good anticoagulation control on vitamin K Antagonists (V...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Proietti M,Lane DA,Lip GY

    更新日期:2016-08-01 00:00:00

  • Elevated copeptin is a prognostic factor for mortality even in patients with renal dysfunction.

    abstract:BACKGROUND:Copeptin has turned out to give valuable prognostic information for future cardiovascular events. However, since its plasma concentration directly depends on renal function, the value of copeptin as a predictor for outcome also in patients with chronic kidney disease (CKD) is unknown. METHODS:In this single...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Engelbertz C,Brand E,Fobker M,Fischer D,Pavenstädt H,Reinecke H

    更新日期:2016-10-15 00:00:00

  • Prognostic significance of silent myocardial ischemia after a first uncomplicated myocardial infarction.

    abstract::Forty asymptomatic patients were studied after a first uncomplicated myocardial infarction. They were 36 men and 4 women, with a mean age of 52.6 yr; the location of myocardial infarction was in the anterior wall in 18 (45%) patients and in the inferior wall in 22 (55%). The patients were submitted to: (1) 48-h Holter...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Solimene MC,Ramires JA,Gruppi CJ,Alfieri RG,de Oliveira SF,Da Luz PL,Pileggi F

    更新日期:1993-01-01 00:00:00

  • Cardiomyopathy: a role for nitric oxide?

    abstract::The negative inotropism, myocardial dilatation and cytotoxicity in inflammatory heart disorders may be due to increased generation of nitric oxide (NO) by immunological induction of a high output NO pathway. This short review discusses the initial experiments which lead to this hypothesis, and evaluates data that this...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: de Belder A,Moncada S

    更新日期:1995-07-01 00:00:00

  • Atrial septal defect in adults > or =40 years old: negative impact of low arterial oxygen saturation.

    abstract:BACKGROUND:Although good prognosis and clinical long-term outcome have been commonly reported in minimally symptomatic adult patients with ASD, this information has been based on studies with a relatively small number of adult patients. We studied unoperated patients aged over 40 years to define the patterns of present...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Rosas M,Attie F,Sandoval J,Castellano C,Buendía A,Zabal C,Granados N

    更新日期:2004-02-01 00:00:00

  • Mid-term results of mitral valve repair for ischemic mitral regurgitation with ETlogix ring: A single-center study.

    abstract:BACKGROUND:Ischemic mitral regurgitation (IMR) is a common complication of coronary artery disease and represents an independent predictor of mortality. In the IMR the pattern of mitral valve annular dilatation is asymmetrical: this can explain the long-term incidence of recurrent mitral regurgitation after surgical an...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Campisi S,Fuzellier JF,Haber B,Favre JP,Gerbay A,Vola M

    更新日期:2016-11-01 00:00:00

  • Sudden cardiac death after PCI and CABG in the bare-metal stent era: Incidence, prevalence, and predictors.

    abstract:BACKGROUND:Few prospective cohort studies have examined the relationship between reduced left ventricular ejection fraction (LVEF) and other comorbidities for precise risk stratification of sudden cardiac death (SCD) after coronary revascularization. METHODS:We analyzed 9877 consecutive patients who underwent first el...

    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Nishiyama K,Shizuta S,Doi T,Morimoto T,Kimura T

    更新日期:2010-10-08 00:00:00

  • Late onset atrioventricular nodal tachycardia.

    abstract::AV nodal tachycardia may present at any age, but onset in late adulthood is considered uncommon. To evaluate whether onset of AV nodal tachycardias at older age is related to organic heart disease (possibly setting the stage for re-entry due to degenerative structural changes) 32 consecutive patients with symptomatic ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Pentinga ML,Meeder JG,Crijns HJ,de Muinck ED,Wiesfeld AC,Lie KI

    更新日期:1993-03-01 00:00:00

  • Management of cardiac myxoma during pregnancy: a case series and review of the literature.

    abstract::Cardiac myxomas are the most common primary benign tumors of the heart. The reported incidence during pregnancy is extremely low with only 17 reported cases in the medical literature. Standard therapy involves surgical resection given the potential for embolization. In the pregnant patient, however, the risks of embol...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: John AS,Connolly HM,Schaff HV,Klarich K

    更新日期:2012-03-08 00:00:00

  • Prognostic power of NT-proBNP in left ventricular non-compaction cardiomyopathy.

    abstract:BACKGROUND:The risk of adverse events in patients with left ventricular non-compaction cardiomyopathy (LVNC) is substantial. This study was designed to determine the prognostic value of NT-proBNP, left ventricular ejection fraction (LVEF), NYHA class, and exercise capacity in LVNC patients. METHODS:Cox regression anal...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Stämpfli SF,Erhart L,Hagenbuch N,Stähli BE,Gruner C,Greutmann M,Niemann M,Kaufmann BA,Jenni R,Held L,Tanner FC

    更新日期:2017-06-01 00:00:00

  • Novel ECG parameters are strongly associated with inflammatory 18F-FDG PET findings in patients with suspected cardiac sarcoidosis.

    abstract:BACKGROUND:18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) is a feasible method to investigate the inflammatory activity of the myocardium in cardiac sarcoidosis. However, PET is costly and not as widely available as standard electrocardiogram (ECG). Current ECG findings related to cardiac sarcoidosis a...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Sipilä K,Tuominen H,Haarala A,Tikkakoski A,Kähönen M,Nikus K

    更新日期:2017-12-15 00:00:00

  • beta-blocker therapy in patients after aortic valve replacement for aortic regurgitation.

    abstract:BACKGROUND:beta-blocker therapy for dilated or ischemic cardiomyopathy is now an accepted and effective treatment. However, little is known about its efficacy in patients with postoperative impaired left ventricular function. This retrospective study was designed to assess the effects of beta-blocker therapy in patient...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Matsuyama K,Ueda Y,Ogino H,Sugita T,Sakakibara Y,Matsubayashi K,Nomoto T,Yoshimura S,Yoshioka T

    更新日期:2000-03-31 00:00:00

  • Lung ultrasound and short-term prognosis in heart failure patients.

    abstract:BACKGROUND:Heart failure (HF) is the leading cause of hospitalization for patients older than 65years, with a 30-day readmission rate of 20-25%. Although several markers have been evaluated to stratify timing of follow-up after an acute decompensation is mostly based on clinical judgment. Lung ultrasound (LUS) has been...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Cogliati C,Casazza G,Ceriani E,Torzillo D,Furlotti S,Bossi I,Vago T,Costantino G,Montano N

    更新日期:2016-09-01 00:00:00

  • Statins reduce relapse rate in Takayasu arteritis.

    abstract:BACKGROUND:To investigate the effect of statins on relapse of Takayasu arteritis (TAK), which frequently occurs after achievement of remission. METHODS:We conducted a retrospective study on TAK patients with active disease, diagnosed between 2012 and 2017. Relapse was defined as recurrence of active disease after achi...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Kwon OC,Oh JS,Park MC,Hong S,Lee CK,Yoo B,Kim YG

    更新日期:2019-07-15 00:00:00

  • Surgical treatment of Takayasu's arteritis.

    abstract::Takayasu's disease is an unusual arteritis that affects young females. Stroke is a common presenting symptom usually due to sudden occlusion of one or more thoracic aortic arch arteries. The author recommends prophylactic bypass of involved aortic arch arteries to prevent strokes. Abdominal aortic involvement causes s...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Giordano JM

    更新日期:2000-08-31 00:00:00

  • Mitochondrial oxidative stress, endothelial function and metabolic control in patients with type II diabetes and periodontitis: A randomised controlled clinical trial.

    abstract:BACKGROUND:Periodontitis (PD) and type 2 diabetes (T2D) are characterized by increased mitochondrial oxidative stress production (mtROS), which has been associated with a greater risk of cardiovascular diseases (CVD). Intensive PD treatment (IPT) can significantly improve endothelial function and metabolic control, alt...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,随机对照试验


    authors: Masi S,Orlandi M,Parkar M,Bhowruth D,Kingston I,O'Rourke C,Virdis A,Hingorani A,Hurel SJ,Donos N,D'Aiuto F,Deanfield J

    更新日期:2018-11-15 00:00:00

  • Cannabis-induced coronary artery thrombosis and acute anterior myocardial infarction in a young man.

    abstract::Information concerning acute myocardial infarction after cannabis usage is limited and the actual mechanism of cannabis-induced myocardial infarction is not well known. In the report, we described a young man with an acute myocardial infarction and cannabis-induced coronary thrombosis. ...

    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Tatli E,Yilmaztepe M,Altun G,Altun A

    更新日期:2007-09-03 00:00:00

  • Gender differences among Norwegian patients with heart failure.

    abstract:BACKGROUND:Recent studies have suggested differences in outcome and treatment between men and women with heart failure. The aim of this study was to see if there were gender differences in the treatment and outcome in real life heart failure patients. METHODS:Norwegian Heart Failure Registry was used. Three-thousand-s...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究


    authors: Brandsaeter B,Atar D,Agewall S,Norwegian Heart failure Registry.

    更新日期:2011-02-03 00:00:00

  • Critical potential of early cardiac surgery for infective endocarditis with cardio-embolic strokes.

    abstract:BACKGROUND:Early cardiac surgery may have a trade-off between stabilized hemodynamics with controlled infection and a risk of peri-operative death in patients with infective endocarditis (IE) complicated with cardio-embolic strokes. METHODS:We retrospectively studied clinical characteristics and outcomes in 68 consecu...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Suzuki M,Takanashi S,Ohshima Y,Nagatomo Y,Seki A,Takamisawa I,Tobaru T,Naito K,Kin H,Umemura J,Takayama M,Sumiyoshi T,Tomoike H

    更新日期:2017-01-15 00:00:00

  • Hypotension during exercise caused by venodilatation.

    abstract::A 54-year-old woman without organic heart disease presented with presyncopal symptoms during work. A decreased cardiac output was demonstrated by haemodynamic measurements during exercise. Treatment with fludrocortisone and ephedrine was initiated with a good haemodynamic and symptomatic result. ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Rohold A,Svanegaard J,Thayssen P

    更新日期:1990-01-01 00:00:00

  • Current status of thromboangiitis obliterans (Buerger's disease) in Japan.

    abstract::We analysed clinical features and outcome in 850 patients with thromboangiitis obliterans (TAO), based on the 1993 Nationwide Survey of Vasculitis database collected from 3722 clinical sites in Japan. The survey was designed to assess clinical manifestation categorized by Fontaine's classification, distribution of les...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Sasaki S,Sakuma M,Yasuda K

    更新日期:2000-08-31 00:00:00

  • Prognostic role of inducible ventricular tachycardia in patients with dilated cardiomyopathy and asymptomatic nonsustained ventricular tachycardia.

    abstract::We studied the prognostic relevance of inducible ventricular tachycardia in 32 patients with dilated cardiomyopathy and spontaneous nonsustained asymptomatic ventricular tachycardia. Programmed ventricular stimulation included basic drive cycle lengths of 600, 500, 430, 370, 330 and 300 msec at single, double, and tri...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Gössinger HD,Jung M,Wagner L,Stain C,Siostrzonek P,Schwarzinger I,Mösslacher H

    更新日期:1990-11-01 00:00:00

  • Characteristics and outcomes of patients requiring bailout use of glycoprotein IIb/IIIa inhibitors for thrombotic complications of percutaneous coronary intervention: An analysis from the CHAMPION PHOENIX trial.

    abstract:AIMS:To describe the characteristics and outcomes of patients receiving bailout glycoprotein IIb/IIIa inhibitors (GPI) for thrombotic complications of percutaneous coronary intervention (PCI) in a large, contemporary trial. METHODS AND RESULTS:In the CHAMPION PHOENIX trial, the use of GPI was restricted to bailout for...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,随机对照试验


    authors: Abtan J,Ducrocq G,Steg PG,Stone GW,Mahaffey KW,Gibson CM,Hamm C,Price MJ,Prats J,Elkin S,Deliargyris EN,White HD,Menozzi A,Harrington RA,Bhatt DL,MPH on Behalf of the CHAMPION PHOENIX Investigators.

    更新日期:2019-03-01 00:00:00

  • Long-term prognosis after hospital admission for acute myocardial infarction from 1987 to 2006.

    abstract:BACKGROUND:Recent population-based estimates for long-term cardiovascular disease (CVD) mortality after hospitalization for a first acute myocardial infarction (AMI) are not well established. METHODS:Data from the Swedish hospital discharge and death registries were used to record all first-ever hospital admissions in...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究


    authors: Dudas K,Lappas G,Rosengren A

    更新日期:2012-03-22 00:00:00

  • The importance of right ventricular evaluation in risk assessment and therapeutic strategies: Raising the bar in pulmonary arterial hypertension.

    abstract::Pulmonary arterial hypertension is an obstructive pulmonary vasculopathy that leads to increased pulmonary vascular resistance, right ventricular overload and failure, and death. Patients' clinical status and prognosis depend mostly on the capability of the right ventricle to adapt to the increased afterload, maintain...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: Badagliacca R,Papa S,Matsubara H,Lang IM,Poscia R,Manzi G,Vizza CD

    更新日期:2020-02-15 00:00:00

  • Right anterior mini-thoracotomy direct aortic self-expanding trans-catheter aortic valve implantation: A single center experience.

    abstract:OBJECTIVE:Transcatheter aortic valve implantation (TAVI) has been designed to treat elderly patients with severe aortic stenosis at high risk for surgery. These patients are also often affected by severe iliac-femoral arteriopathy, rendering the trans-femoral approach unusable. We report our experience with the direct-...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Bruschi G,De Marco F,Botta L,Barosi A,Colombo P,Mauri S,Cannata A,Morici N,Colombo T,Fratto P,Nonini S,Soriano F,Mondino M,Giannattasio C,Klugmann S

    更新日期:2015-02-15 00:00:00

  • Cardiovascular risk and hypertension control in Italy. Data from the 2015 World Hypertension Day.

    abstract:BACKGROUND:Cardiovascular diseases (CVD) are the first cause of death and disability in western countries. Despite therapeutic advances, their prevalence is constantly increasing. Detailed assessment of modifiable CV risk factors could improve CVD prevention and management. METHODS:to assess CV risk and hypertension c...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Torlasco C,Faini A,Makil E,Ferri C,Borghi C,Veglio F,Desideri G,Agabiti Rosei E,Ghiadoni L,Pauletto P,Pontremoli R,Stornello M,Tocci G,Galletti F,Trimarco B,Parati G,Council of the Italian Society of Hypertension.

    更新日期:2017-09-15 00:00:00

  • Prognostic significance of exercise thallium-201 myocardial perfusion imaging compared to stress echocardiography and clinical variables in patients with unstable angina who respond to medical treatment.

    abstract::The prognostic value of thallium-201 imaging in patients with unstable angina is not well established. Forty consecutive patients with unstable angina who had responded to medical therapy underwent predischarge symptom-limited exercise testing and 39 of them underwent exercise thallium-201 imaging, on average 3 days a...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Amanullah AM,Lindvall K,Bevegård S

    更新日期:1993-04-01 00:00:00

  • Trends in case-fatality in 22968 patients admitted for the first time with atrial fibrillation in Scotland, 1986-1995.

    abstract:BACKGROUND:Although atrial fibrillation (AF) is an important cause of cardiovascular morbidity and mortality there is a paucity of data describing hospitalisation rates and case-fatality associated with this common arrhythmia. This study examines recent trends in first-ever hospitalisations for AF in Scotland. METHODS...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Stewart S,MacIntyre K,Chalmers JW,Boyd J,Finlayson A,Redpath A,Pell JP,Capewell S,McMurray JJ

    更新日期:2002-03-01 00:00:00