Abstract：
:This study evaluated the effect of different concentrations of 2-hydroxyethyl methacrylate (HEMA) on the inhibition of matrix metalloproteinase-2 (MMP-2) in vitro. Mouse gingival explants were cultured overnight in Dulbecco's modified Eagle's minimal essential medium, following which the expression of secreted enzymes was analyzed by gelatin zymography and the effects of different amounts of HEMA on enzyme activity were investigated. The gelatinolytic proteinases present in the conditioned media were characterized as being matrix metalloproteinases (MMPs) by means of specific chemical inhibition. The MMPs present in the conditioned media were identified, using immunoprecipitation, as MMP-2. Three major bands were detected in the zymographic assays and were characterized, according to their respective molecular weights, into the following forms of MMP-2: zymogene (72 kDa), intermediate (66 kDa), and active (62 kDa). All forms of MMP-2 were inhibited by HEMA in a dose-dependent manner, implying that MMP-2 may be inhibited by HEMA in vivo.
journal_name
Eur J Oral Scijournal_title
European journal of oral sciencesauthors
Carvalho RV,Ogliari FA,de Souza AP,Silva AF,Petzhold CL,Line SR,Piva E,Etges Adoi
10.1111/j.1600-0722.2008.00591.xsubject
Has Abstractpub_date
2009-02-01 00:00:00pages
64-7issue
1eissn
0909-8836issn
1600-0722pii
EOS591journal_volume
117pub_type
杂志文章abstract：:This study evaluated the effect of topical fluoride application on enamel hardness after in-office bleaching. Twelve human incisors were cut along the long axis, resulting in 24 halves used in four treatment groups (n = 6 in each group): (i) untreated group (C); (ii) in-office bleaching material (B); (iii) treatment w...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/eos.12386
更新日期：2017-12-01 00:00:00
abstract：:There is evidence that the quantity of antigen load is crucial for the activation of IgA immune responses. In order to investigate the relevance of these findings in aggressive periodontitis, salivary antibody responses were measured during non-surgical and antibiotic treatment. Twenty-one patients with generalized ag...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1034/j.1600-0722.2003.00040.x
更新日期：2003-06-01 00:00:00
abstract：:Granulocyte elastase was determined in the gingival crevicular fluid (GCF) of 18 periodontitis patients. They initially had similar severity of disease but had responded differently to 5-yr maintenance, 13 responders and 5 non-responders. A total of 102 sites were investigated and categorized as: i) consistently healt...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.1995.tb00121.x
更新日期：1995-04-01 00:00:00
abstract：:Treatment programs to prevent perinatal and postnatal HIV-1 transmission have become available in sub-Saharan Africa, leading to an emerging population of HIV-1 exposed uninfected (HEU) children. Exposure to HIV-1 in utero and during breastfeeding may increase the risk of morbidity and mortality in HEU children. This ...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/eos.12669
更新日期：2020-02-01 00:00:00
abstract：:Ectopic tooth transplants are known to receive rich innervation of local neurons, but the precise location and structural features of neurites in the pulp and periodontal ligament (PDL) of such transplants are unclear. In this experiment, the molar tooth germs of rat embryos and incisors of young rats were subcutaneou...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2008.00546.x
更新日期：2008-08-01 00:00:00
abstract：:Oral health problems are reported more frequently in children with disabilities, but the reasons for this are not fully known. The present study was conducted to illuminate and to gain a deeper understanding of the possible barriers preventing children with disabilities from receiving oral health care on the same prem...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2012.00961.x
更新日期：2012-06-01 00:00:00
abstract：:This study aimed to investigate the effect of glutamate-evoked masseter muscle pain on intramuscular oxygenation during rest and sustained elevated muscle activity (SEMA). Seventeen healthy individuals participated in two sessions in which they were injected with glutamate and saline in random order. Each session was ...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/eos.12383
更新日期：2017-12-01 00:00:00
abstract：:This study compared SYBR Green real-time quantitative PCR (qPCR) with standard plate counting for the enumeration of Streptococcus mutans in oral samples. Oral samples (n = 710) were collected from high-caries-risk children for quantification of S. mutans by qPCR using primer pairs. The S. mutans copy number was calcu...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2011.00888.x
更新日期：2011-12-01 00:00:00
abstract：:Resin infiltration of non-cavitated proximal caries lesions has been shown to inhibit further demineralization. However, the effect of resin infiltration in cavitated lesions is unknown. Therefore, the aim of this in vitro study was to evaluate infiltration patterns of proximal caries lesions differing in Internationa...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2011.00807.x
更新日期：2011-04-01 00:00:00
abstract：:The aim of this study was to visualize fluid movement through dental enamel in vivo. Fifty permanent upper central incisors, from subjects aged 10-70 yr, and 5 permanent central just-erupted incisors, from subjects aged 6-7 yr, were included in the study. An impression was obtained by vinyl polyxiloxane, and replicas ...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2007.00445.x
更新日期：2007-06-01 00:00:00
abstract：:This study investigated the effect of low-power, non-thermal atmospheric pressure plasma (NT-APP) treatments, in pulsed and conventional modes, on the adhesion of resin composite to dentin and on the durability of the bond between resin composite and dentin. A pencil-type NT-APP jet was applied in pulsed and conventio...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/eos.12153
更新日期：2014-12-01 00:00:00
abstract：:Genetic factors underlie the susceptibility and the resistance to dental fluorosis (DF). The A/J (DF susceptible) and 129P3/J (DF resistant) mouse strains have previously been used to detect quantitative trait loci (QTLs) associated with DF on chromosome (Chr) 2 and Chr 11. In the present study, increased marker densi...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2011.00868.x
更新日期：2011-12-01 00:00:00
abstract：:The renin-angiotensin system is thought to be involved in inflammatory processes such as periodontitis. However, its precise role is still unclear. Therefore, in the present study the expression of the angiotensin II type 1 receptor (AT1R) was investigated in inflamed human gingival tissue, and the possible involvemen...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2011.00850.x
更新日期：2011-10-01 00:00:00
abstract：:The aims were to test the hypotheses that experimental masseter muscle pain leads to recruitment and/or derecruitment of motor units at different sites within the masseter and that the patterns of change in motor unit activity differ between sites. Single motor unit (SMU) activity was recorded at two sites within the ...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/eos.12561
更新日期：2018-10-01 00:00:00
abstract：:As a result of their presence throughout the mouth in the submucosa or between muscle fibers, minor salivary glands secrete directly and continuously into the oral cavity, providing mucosal surfaces with highly glycosylated proteins that are active in bacterial aggregation and in oral tissue lubrication. In this study...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2009.00700.x
更新日期：2010-02-01 00:00:00
abstract：:Originally identified as the active components within osteoinductive extracts derived from bone, the BMPs now are known to include a large family of proteins within the TGF-beta superfamily of growth and differentiation factors. Members of the BMP family have been determined to be key signaling molecules in embryogene...
journal_title：European journal of oral sciences
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0722.1998.tb02170.x
更新日期：1998-01-01 00:00:00
abstract：:The non-stick properties of thin-film coatings on dental-restorative instruments were investigated by static contact-angle measurement using dental filler resin as well as by scanning electron microscopy of the amount of sticking dental restorative material. Furthermore, using a customized dipping measurement set-up, ...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/eos.12372
更新日期：2017-12-01 00:00:00
abstract：:Recent thinking about the role of regional socioeconomic context in generating health inequalities has argued for the collection of true 'area' data that accurately reflect the characteristics of a region. We investigated whether a range of attributes of regional environments, constructed from factor analysis of vario...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2011.00831.x
更新日期：2011-08-01 00:00:00
abstract：:Patients with cardiac implantable electrical devices should take precautions when exposed to electromagnetic fields. Possible interference as a result of proximity to electromagnets or electricity flow from electronic tools employed in clinical odontology remains controversial. The objective of this study was to exami...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/eos.12183
更新日期：2015-06-01 00:00:00
abstract：:An oxygen inhibition layer develops on surfaces exposed to air during polymerization of particulate filling composite. This study assessed the thickness of the oxygen inhibition layer of short-fiber-reinforced composite in comparison with conventional particulate filling composites. The effect of an oxygen inhibition ...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/eos.12167
更新日期：2015-02-01 00:00:00
abstract：:The objective of this clinical study was to assess the internal and marginal accuracy of computer-aided design/computer-aided manufacturing (CAD/CAM)-generated four-unit all-ceramic posterior fixed dental prostheses (FDPs). The data were compared with the results of three-unit metal-ceramic and all-ceramic FDPs that w...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2008.00580.x
更新日期：2008-12-01 00:00:00
abstract：:Subepithelial soft tissue and bone obtained from the implant bed in the vicinity of stainless steel and titanium miniplates and screws were evaluated with respect to the presence of immunocompetent cells. The study included tissue specimens from 19 patients, in whom the implants (14 stainless steel and 5 titanium) had...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.1995.tb00010.x
更新日期：1995-02-01 00:00:00
abstract：:This study tested the fluoride-release rate and the root caries inhibitory effect of dental adhesives. In phase 1, the fluoride released from samples (n = 5) of the adhesives A (Optibond Solo), B (One-up Bond F), C (Prime & Bond NT), D (Tenure Quick), and also of the controls [+] (glass-ionomer cement) and [-] (non-fl...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2005.00214.x
更新日期：2005-06-01 00:00:00
abstract：:The amelogenin proteins are required for normal enamel development, and the most abundant amelogenins expressed from alternatively spliced mRNAs are M180 and leucine-rich amelogenin protein (LRAP). The X-Chromosomal Amelogenin (Amelx) null [knockout (KO)] mouse has an enamel defect similar to human X-linked amelogenes...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2011.00882.x
更新日期：2011-12-01 00:00:00
abstract：:Self-etching primers and adhesives contain very hydrophilic methacrylate monomers that result in high water sorptions by their polymers. Water sorption plasticizes the polymers and lowers their mechanical properties. The purpose of this work was to rank the hydrophilicity of a series of acidic primers by their Hoy's s...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2007.00452.x
更新日期：2007-06-01 00:00:00
abstract：:A derivative (EMD) of enamel matrix proteins (EMPs) is used for periodontal regeneration because EMPs are believed to induce the formation of acellular extrinsic fiber cementum (AEFC). Other reports, however, indicate that EMPs have osteogenic potential. The aim of this study was to characterize the nature of the tiss...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2006.00300.x
更新日期：2006-05-01 00:00:00
abstract：:The aim of this study was to assess post-trial treatment costs, clinical outcomes [decayed, missing or filled surfaces (DMFS) scores], and utilization of dental services among adolescents who had participated in a randomized clinical trial (RCT) in Pori, Finland, in 2001-2005. At baseline the children were 11-12 yr of...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2010.00726.x
更新日期：2010-06-01 00:00:00
abstract：:The aims of this study were to evaluate the effect of two caries-preventive programs, and to apply the laser fluorescence method, DIAGNOdent, for longitudinal quantification of changes in incipient carious lesions. Twelve subjects with 127 test teeth exhibiting white spot lesions on the buccal surfaces after completed...
journal_title：European journal of oral sciences
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-0722.2006.00395.x
更新日期：2006-10-01 00:00:00
abstract：:High mobility group protein B1 (HMGB1), a bone-active cytokine and an osteocyte alarmin, might have dual functions in bone metabolism that could benefit bone formation and accelerate osteoclastogenic activity. High mobility group protein B1 was recently shown to be involved in tooth movement. Here, we investigated the...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/eos.12644
更新日期：2019-10-01 00:00:00
abstract：:The aim of the present study was to examine the accuracy of linear measurements on radiographs of interproximal bone loss in intrabony defects utilizing the gold standard of surgical measurements. In 22 patients with untreated advanced periodontal disease, 33 standardized radiographs were taken presurgically. The hori...
journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1034/j.1600-0722.2000.00729.x
更新日期：2000-02-01 00:00:00
