Abstract：
:Treatment programs to prevent perinatal and postnatal HIV-1 transmission have become available in sub-Saharan Africa, leading to an emerging population of HIV-1 exposed uninfected (HEU) children. Exposure to HIV-1 in utero and during breastfeeding may increase the risk of morbidity and mortality in HEU children. This study estimated the association of the severity of maternal HIV-1 infection as assessed by CD4 count and viral load at baseline (7 d postpartum), with dmft count of their 5- to 7-yr-old HEU offspring. A follow-up study was conducted of HIV-1-infected mother-HEU children pairs (n = 164) from the Ugandan site of the ANRS 12341-PROMISE- PEP trial (ClinicalTrials.gov, number NCT00640263). HIV-1-infected mothers were interviewed and the HEU children were examined for caries using the World Health Organization's survey methods for field conditions and the dmft index. Directed acyclic graphs and negative binomial regression were used for analyses. The prevalence of 1 or more dmft was 48%. Negative binomial regression showed no association between the dmft count and maternal CD4 counts 7 d postpartum but a 10% lower dmft count with longer breastfeeding duration was found. Maternal CD4 count at birth was not associated with the dental caries experience in uninfected children born to women without severe immune suppression, while there appeared to be a protective effect of high viral load and breastfeeding duration.
journal_name
Eur J Oral Scijournal_title
European journal of oral sciencesauthors
Birungi N,Fadnes LT,Engebretsen IMS,Lie SA,Tumwine JK,Åstrøm AN,ANRS 12174 and 12341 study groups.doi
10.1111/eos.12669subject
Has Abstractpub_date
2020-02-01 00:00:00pages
46-54issue
1eissn
0909-8836issn
1600-0722journal_volume
128pub_type
杂志文章abstract：:This study tested the fluoride-release rate and the root caries inhibitory effect of dental adhesives. In phase 1, the fluoride released from samples (n = 5) of the adhesives A (Optibond Solo), B (One-up Bond F), C (Prime & Bond NT), D (Tenure Quick), and also of the controls [+] (glass-ionomer cement) and [-] (non-fl...
journal_title：European journal of oral sciences
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abstract：:Because low-fluoride toothpaste (500 p.p.m. F) has not clearly been shown to be effective for controlling caries in caries-active children, this experimental in situ study was conducted to evaluate whether its effect, when compared with a conventional toothpaste (1,000-1,500 p.p.m. F), would depend on the cariogenic c...
journal_title：European journal of oral sciences
pub_type： 杂志文章,随机对照试验
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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doi：10.1111/j.1600-0722.2011.00807.x
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
pub_type： 杂志文章,随机对照试验
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
pub_type： 杂志文章
doi：10.1111/j.1600-0722.2004.00169.x
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journal_title：European journal of oral sciences
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doi：10.1111/j.1600-0722.2008.00546.x
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
pub_type： 杂志文章
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更新日期：2012-12-01 00:00:00
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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journal_title：European journal of oral sciences
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