Abstract：
INTRODUCTION:In vivo and in vitro evidence suggests that adenosine and its agonists play key roles in the process of ischemic preconditioning. The effects of low-dose adenosine infusion on ischemic preconditioning have not been thoroughly studied in humans. AIMS:We hypothesised that a low-dose adenosine infusion could reduce the ischemic burden evoked by physical exercise and improve the regional left ventricular (LV) systolic function. MATERIALS AND METHODS:We studied nine severely symptomatic male patients with severe coronary artery disease. Myocardial ischemia was induced by exercise on two separate occasions and quantified by Tissue Doppler Echocardiography. Prior to the exercise test, intravenous low-dose adenosine or placebo was infused over ten minutes according to a randomized, double blind, cross-over protocol. The LV walls were defined as ischemic if a reduction, no increment, or an increment of < 15% in peak systolic velocity (PSV) was observed during maximal exercise compared to the baseline values observed prior to placebo-infusion. Otherwise, the LV walls were defined as non-ischemic. RESULTS:PSV increased from baseline to maximal exercise in non-ischemic walls both during placebo (P = 0.0001) and low-dose adenosine infusion (P = 0.0009). However, in the ischemic walls, PSV increased only during low-dose adenosine infusion (P = 0.001), while no changes in PSV occurred during placebo infusion (P = NS). CONCLUSION:Low-dose adenosine infusion reduced the ischemic burden and improved LV regional systolic function in the ischemic walls of patients with exercise-induced myocardial ischemia, confirming that adenosine is a potential preconditioning agent in humans.
journal_name
Cardiovasc Ultrasoundjournal_title
Cardiovascular ultrasoundauthors
Sadigh B,Quintana M,Sylvén C,Berglund M,Brodin LAdoi
10.1186/1476-7120-7-52subject
Has Abstractpub_date
2009-11-05 00:00:00pages
52issn
1476-7120pii
1476-7120-7-52journal_volume
7pub_type
杂志文章,随机对照试验abstract：BACKGROUND:Although echocardiography has been incorporated into the diagnostic algorithm of patients with suspected infective endocarditis (IE), systematic usage in clinical practice remains ill defined. To determine the diagnostic accuracy of detecting vegetations using harmonic transthoracic echocardiography (hTTE) a...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-5-20
更新日期：2007-05-19 00:00:00
abstract：BACKGROUND:Adrenocortical carcinoma is a rare, highly malignant tumor. Cardiac involvement of the tumor is very rare. Echocardiography facilitates the evaluation of the cardiac involvement of the tumor. CASE PRESENTATION:We describe a patient with an adrenal tumor. Transthoracic echo showed its extension into the righ...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-1-5
更新日期：2003-05-16 00:00:00
abstract：BACKGROUND:Calcification is an independent predictor of mortality in calcific aortic valve disease (CAVD). The aim of this study was to evaluate the use of non-invasive, non-ionizing echocardiographic calibrated integrated backscatter (cIB) for monitoring progression and subsequent regression of aortic valvular calcifi...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-11-4
更新日期：2013-01-26 00:00:00
abstract：BACKGROUND:Theoretically, a cross-sectional image of any cardiac planes can be obtained from a STIC fetal heart volume dataset. We described a method to display 11 fetal echocardiographic planes from STIC volumes. METHODS:Fetal heart volume datasets were acquired by transverse acquisition from 200 normal fetuses at 15...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-8-41
更新日期：2010-09-15 00:00:00
abstract：OBJECTIVES:To describe the findings and evaluate appropriateness of a carotid artery study including the measurement of IMT, the presence of atherosclerotic plaque, and their correlation with cardiovascular risk factors. METHODS:555 patients (220 men; 67.06 +/- 12.44 years) were included in the study. 120 patients (21...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-6-52
更新日期：2008-10-16 00:00:00
abstract：PURPOSE:Left ventricular (LV) wall thickness can be measured at the posterior wall (PW) and the intraventricular septum (IVS) in a parasternal long axis view by transthoracic echocardiography. Thus, there are three methods to calculate relative wall thickness as follows: RWTPW = 2 × PWth/LVDd; RWTIVS + PW = (IVSth + PW...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/s12947-019-0179-6
更新日期：2019-12-03 00:00:00
abstract：BACKGROUND:Transthoracic echocardiography (TTE) may be used for direct inspection of various parts of the main coronary arteries for detection of coronary stenoses and occlusions. We aimed to assess the feasibility of TTE to visualise the complete segments of the left main (LM), left descending (LAD), circumflex (Cx) a...
journal_title：Cardiovascular ultrasound
pub_type： 临床试验,杂志文章
doi：10.1186/1476-7120-7-58
更新日期：2009-12-22 00:00:00
abstract：BACKGROUND:In the last recent years a new percutaneous procedure, the MitraClip, has been validated for the treatment of mitral regurgitation. MitraClip procedure is a promising alternative for patients unsuitable for surgery as it reduces the risk of death related to surgery ensuring a similar result. Few data are pre...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-11-13
更新日期：2013-05-04 00:00:00
abstract：BACKGROUND:The contractile response of patients with heart failure (HF) may be assessed by exercise stress echocardiography (ESE)-derived indexes. We sought to test whether ESE parameters are useful to identify the risk of adverse left ventricular (LV) remodeling in patients with chronic HF and reduced or mildly reduce...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/s12947-019-0157-z
更新日期：2019-04-06 00:00:00
abstract：:In this case report we describe a rare case of right atrium myxoma that coexisted with antiphospholipid syndrome in a young woman. We describe the unusual findings and diagnostic challenges combined with a review of the literature. ...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-7-47
更新日期：2009-10-11 00:00:00
abstract：:A 63-year-old man was admitted to our hospital with a complaint of right lateroabdominal pain. He was diagnosed with metastatic colon cancer, and then developed multiple brain embolic infarctions 7 days after admission. Transesophageal echocardiography showed that mobile, echo-dense masses were attached to the anterio...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-9-8
更新日期：2011-02-28 00:00:00
abstract：BACKGROUND:The most widely used experimental models of infective endocarditis (IE) are the rabbit and rat models, in which cardiac valve lesions are induced by a polyethylene catheter introduced into the left ventricle through the aortic valve. Our study was designed to create a rabbit model of IE right-sided with echo...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-11-3
更新日期：2013-01-14 00:00:00
abstract：OBJECTIVE:Left ventricular wall stress has been investigated in a variety of populations, but the effect of food intake has not been evaluated. We assessed whether left ventricular wall stress is affected by food intake in healthy subjects. METHODS:Twenty-three healthy subjects aged 25.6 ± 4.5 years were investigated....
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-12-2
更新日期：2014-01-28 00:00:00
abstract：BACKGROUND:Non-ischemic dilated cardiomyopathy (DCM) is the most common cardiomyopathy worldwide, with significant mortality. Correct evaluation of the patient's myocardial function has important clinical significance in the diagnosis, therapeutic effect assessment and prognosis in non-ischemic DCM patients. This study...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-10-8
更新日期：2012-03-07 00:00:00
abstract：BACKGROUND:A hybrid approach to minimally invasive perventricular closure of VSD in infants is safe and effective, and has been performed under guidance of transesophageal echocardiography (TEE). We applied transthoracic echocardiographic (TTE) guidance to this hybrid approach, and compare results guided by TTE with th...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-11-8
更新日期：2013-03-11 00:00:00
abstract：:This review article is aimed at comparing the results of histopathological and clinical imaging studies to assess coronary collateral circulation in humans. The role of collaterals, as emerging from morphological studies in both normal and atherosclerotic coronary vessels, is described; in addition, present role and f...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章,评审
doi：10.1186/1476-7120-3-6
更新日期：2005-03-01 00:00:00
abstract：:Real-time three-dimensional (RT-3D) echocardiography has entered the clinical practice but true incremental value over standard two-dimensional echocardiography (2D) remains uncertain when applied to stress echo. The aim of the present study is to establish the additional value of RT-3D stress echo over standard 2D st...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-6-31
更新日期：2008-06-20 00:00:00
abstract：BACKGROUND:Use of preoperative echocardiography may help to identify patients with increased cardiac risk, who may benefit from modification of perioperative plan. The objective of our study was to evaluate the reliability of preoperative focused cardiac ultrasound (FoCUS) performed by an anaesthetist with basic ultras...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/s12947-015-0039-y
更新日期：2015-11-20 00:00:00
abstract：:Persistent left superior vena cava is rare but important congenital vascular anomaly. It results when the left superior cardinal vein caudal to the innominate vein fails to regress. It is most commonly observed in isolation but can be associated with other cardiovascular abnormalities including atrial septal defect, b...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章,评审
doi：10.1186/1476-7120-6-50
更新日期：2008-10-10 00:00:00
abstract：BACKGROUND:The morning hours are associated with increased cardiovascular (CV) risk, and vascular endothelial function (VEF) is a strong predictor of CV disease. A diurnal rhythm in VEF has been established but the morning variation in VEF is not well-documented. Thus, we tested if VEF is impaired across the vulnerable...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/s12947-015-0036-1
更新日期：2015-10-05 00:00:00
abstract：:A high incidence of left ventricular diastolic dysfunction and increased risk of cardiovascular events have been reported in patients with diabetes mellitus. Sodium glucose cotransporter 2 (SGLT2) inhibitors selectively inhibit kidney glucose and sodium reabsorption, and cardiovascular benefits of SGLT2 inhibitors bey...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/s12947-019-0177-8
更新日期：2019-11-13 00:00:00
abstract：BACKGROUND:The goal of this study was to determine if left ventricular (LV) global longitudinal strain (GLS) predicts heart failure (HF) readmission in patients with acute decompensated heart failure. METHODS AND RESULTS:Two hundred ninety one patients were enrolled at the time of admission for acute decompensated hea...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/s12947-017-0098-3
更新日期：2017-03-15 00:00:00
abstract：BACKGROUND:The aim of this study was to define the independent determinants of left atrial appendage (LAA) thrombus among various echocardiographic parameters measured by Velocity Vector Imaging (VVI) in patients with nonvalvular atrial fibrillation (AF) receiving warfarin, particularly in patients with a low CHADS2 sc...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-10-50
更新日期：2012-12-27 00:00:00
abstract：BACKGROUND:Shear Wave Elastography (SWE) imaging is a novel ultrasound technique for quantifying tissue elasticity. Studies have demonstrated that SWE is able to differentiate between diseased and normal tissue in a wide range clinical applications. However its applicability to atherosclerotic carotid disease has not b...
journal_title：Cardiovascular ultrasound
pub_type： 临床试验,杂志文章
doi：10.1186/1476-7120-12-49
更新日期：2014-12-08 00:00:00
abstract：:Miniaturization has evolved in the creation of a pocket-size imaging device which can be utilized as an ultrasound stethoscope. This study assessed the additional diagnostic power of pocket size device by both experts operators and trainees in comparison with physical examination and its appropriateness of use in comp...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-8-51
更新日期：2010-11-26 00:00:00
abstract：BACKGROUND:The percentage of hypertrophic cardiomyopathy (HCM) patients who are in high risk for Sudden Death (SD) constitutes only a minority of all HCM population but the incidence of SD in this subset is high (at least 5% annually). The identification of this small but important proportion of high risk HCM patients ...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-7-37
更新日期：2009-07-26 00:00:00
abstract：INTRODUCTION:Accidental hypothermia is a condition associated with significant morbidity and mortality. Hypothermia has been reported to affect left ventricular systolic and diastolic function. However, most of the data come from animal experimental studies. AIM OF THE STUDY:The purpose of the present study was to ass...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/s12947-015-0027-2
更新日期：2015-07-15 00:00:00
abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) is generally associated with a low to moderate increase of the left ventricular ejection fraction (LVEF). In some patients, however, LVEF improves remarkably and reaches near-normal values. The aim of the present study was to further characterize these so called 'super...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-8-35
更新日期：2010-09-01 00:00:00
abstract：:This review article summarizes the results of histopathological studies to assess heart failure in humans. Different histopathological features underlying the clinical manifestations of heart failure are reviewed. In addition, the present role of echocardiographic techniques in assessing the failing heart is briefly s...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章,评审
doi：10.1186/1476-7120-5-5
更新日期：2007-01-30 00:00:00
abstract：:Supravalvular mitral stenosis is a rare condition characterized by an abnormal ridge, with one or two orifices, covering and obstructing the mitral valve. Preoperative diagnosis is difficult with transtoracic echo (TTE), angiography and magnetic resonance imaging (MRI). In this case, a 36-year-old male, was admitted t...
journal_title：Cardiovascular ultrasound
pub_type： 杂志文章
doi：10.1186/1476-7120-3-19
更新日期：2005-08-11 00:00:00
