Abstract:
BACKGROUND:The contractile response of patients with heart failure (HF) may be assessed by exercise stress echocardiography (ESE)-derived indexes. We sought to test whether ESE parameters are useful to identify the risk of adverse left ventricular (LV) remodeling in patients with chronic HF and reduced or mildly reduced LV ejection fraction (EF). METHODS:We enrolled 155 stabilized patients (age: 62 ± 11 years, 17% female, coronary artery disease 47%) with chronic HF, LV EF ≤50% and LV end-diastolic volume index > 75 ml/m2. All patients underwent a symptom-limited graded bicycle semi-supine ESE, with evaluation of peak stress LV EF, end-systolic pressure-volume relation (ESPVR, i.e. LV elastance) and cardiac power output to LV mass (CPOM). A complete echocardiographic study was performed at baseline and after 6 ± 3 months. Adverse LV remodeling was defined as the association of eccentric LV hypertrophy (LV mass: ≥115 g/m2 for male and ≥ 95 g/m2 for women, and relative wall thickness < 0.32) with an increase in LV end-systolic volume index ≥10% at six months. RESULTS:Adverse LV remodeling was detected in 34 (22%) patients. After adjustment for clinical, biochemical and echocardiographic data, peak ESPVR resulted in the most powerful independent predictor of adverse LV remodeling (OR: 12.5 [95% CI 4.5-33]; p < 0.0001) followed by ischemic aetiology (OR: 2.64 [95% 1.04-6.73]; p = 0.04). CONCLUSION:In patients with HF and reduced or mildly reduced EF, a compromised ESE-derived peak ESPVR, that reflects impaired LV contractility, resulted to be the most powerful predictor of adverse LV remodeling.
journal_name
Cardiovasc Ultrasoundjournal_title
Cardiovascular ultrasoundauthors
Fabiani I,Pugliese NR,Santini C,Miccoli M,D'Agostino A,Rovai I,Mazzola M,Pedrinelli R,Dini FLdoi
10.1186/s12947-019-0157-zsubject
Has Abstractpub_date
2019-04-06 00:00:00pages
6issue
1issn
1476-7120pii
10.1186/s12947-019-0157-zjournal_volume
17pub_type
杂志文章abstract:BACKGROUND:While echocardiographic grading of left ventricular (LV) diastolic dysfunction (DD) is used every day, the relationship between echocardiographic DD grade and hemodynamic abnormalities is uncertain. METHODS:We identified 460 consecutive patients who underwent transthoracic echocardiography within 24 h of el...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-015-0023-6
更新日期:2015-06-24 00:00:00
abstract::A high incidence of left ventricular diastolic dysfunction and increased risk of cardiovascular events have been reported in patients with diabetes mellitus. Sodium glucose cotransporter 2 (SGLT2) inhibitors selectively inhibit kidney glucose and sodium reabsorption, and cardiovascular benefits of SGLT2 inhibitors bey...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-019-0177-8
更新日期:2019-11-13 00:00:00
abstract:BACKGROUND:Aortic valve stenosis (AS) is the most common primary valvular heart disease leading to surgical or percutaneous aortic valve replacement (AVR) in Europe and its prevalence keeps growing. While other risk factors in severe AS are well documented, little is known about the prognostic value of left atrial (LA)...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-020-00231-0
更新日期:2021-01-02 00:00:00
abstract::Pulmonary embolism is a common cardiovascular emergency, but it is still often misdiagnosed due to its unspecific clinical symptoms. Elevated troponin concentrations are associated with greater morbidity and mortality in patients with pulmonary embolism. Right ventricular ischemia due to increased right ventricular af...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-8-50
更新日期:2010-11-24 00:00:00
abstract:BACKGROUND:The aim of this study was to define the independent determinants of left atrial appendage (LAA) thrombus among various echocardiographic parameters measured by Velocity Vector Imaging (VVI) in patients with nonvalvular atrial fibrillation (AF) receiving warfarin, particularly in patients with a low CHADS2 sc...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-10-50
更新日期:2012-12-27 00:00:00
abstract:BACKGROUND:Systemic sclerosis (SSc) is an autoimmune chronic disease characterized by diffuse fibrosis involving several organs, including heart. Aim of our study was to analyze left ventricular (LV) myocardial deformation, by use of 2D strain, in asymptomatic SSc patients with normal LV ejection fraction. METHODS:We ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-11-6
更新日期:2013-02-03 00:00:00
abstract:BACKGROUND:Non-ischemic dilated cardiomyopathy (DCM) is the most common cardiomyopathy worldwide, with significant mortality. Correct evaluation of the patient's myocardial function has important clinical significance in the diagnosis, therapeutic effect assessment and prognosis in non-ischemic DCM patients. This study...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-10-8
更新日期:2012-03-07 00:00:00
abstract:OBJECTIVE:Cardiac resynchronization therapy is proven efficacious in patients with heart failure (HF). Presence of biventricular HF is associated with a worse prognosis than having only left ventricular (LV) HF and pacing might deteriorate heart function. The aim of the study was to assess a possible significance of ri...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-9-28
更新日期:2011-10-26 00:00:00
abstract:BACKGROUND:Theoretically, a cross-sectional image of any cardiac planes can be obtained from a STIC fetal heart volume dataset. We described a method to display 11 fetal echocardiographic planes from STIC volumes. METHODS:Fetal heart volume datasets were acquired by transverse acquisition from 200 normal fetuses at 15...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-8-41
更新日期:2010-09-15 00:00:00
abstract::Global and regional left ventricular (LV) systolic dysfunction is a marker of coronary artery disease (CAD), which is conventionally assessed using two-dimensional echocardiography. Tissue Doppler imaging (TDI) has emerged as an adjunct tool in the diagnosis of regional wall motion abnormalities from CAD. We performed...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章,meta分析,评审
doi:10.1186/1476-7120-10-47
更新日期:2012-11-30 00:00:00
abstract:BACKGROUND:Calcification is an independent predictor of mortality in calcific aortic valve disease (CAVD). The aim of this study was to evaluate the use of non-invasive, non-ionizing echocardiographic calibrated integrated backscatter (cIB) for monitoring progression and subsequent regression of aortic valvular calcifi...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-11-4
更新日期:2013-01-26 00:00:00
abstract::Persistent left superior vena cava is rare but important congenital vascular anomaly. It results when the left superior cardinal vein caudal to the innominate vein fails to regress. It is most commonly observed in isolation but can be associated with other cardiovascular abnormalities including atrial septal defect, b...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章,评审
doi:10.1186/1476-7120-6-50
更新日期:2008-10-10 00:00:00
abstract:OBJECTIVE:Left ventricular wall stress has been investigated in a variety of populations, but the effect of food intake has not been evaluated. We assessed whether left ventricular wall stress is affected by food intake in healthy subjects. METHODS:Twenty-three healthy subjects aged 25.6 ± 4.5 years were investigated....
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-12-2
更新日期:2014-01-28 00:00:00
abstract:OBJECTIVES:To describe the findings and evaluate appropriateness of a carotid artery study including the measurement of IMT, the presence of atherosclerotic plaque, and their correlation with cardiovascular risk factors. METHODS:555 patients (220 men; 67.06 +/- 12.44 years) were included in the study. 120 patients (21...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-6-52
更新日期:2008-10-16 00:00:00
abstract::A 63-year-old man was admitted to our hospital with a complaint of right lateroabdominal pain. He was diagnosed with metastatic colon cancer, and then developed multiple brain embolic infarctions 7 days after admission. Transesophageal echocardiography showed that mobile, echo-dense masses were attached to the anterio...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-9-8
更新日期:2011-02-28 00:00:00
abstract:BACKGROUND:The goal of this study was to determine if left ventricular (LV) global longitudinal strain (GLS) predicts heart failure (HF) readmission in patients with acute decompensated heart failure. METHODS AND RESULTS:Two hundred ninety one patients were enrolled at the time of admission for acute decompensated hea...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-017-0098-3
更新日期:2017-03-15 00:00:00
abstract:BACKGROUND:The developments in echocardiography or ultrasound cardiography (UCG) have improved our clinical capabilities. However, advanced hardware and software capabilities have resulted in UCG facilities of dubious clinical benefits. Is tissue Doppler echocardiography (TDE) is one such example? PRESENTATION OF THE ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-2-12
更新日期:2004-08-12 00:00:00
abstract:BACKGROUND:Left ventricular (LV) ejection fraction (LVEF) assessed by two-dimensional echocardiography (2DE) is the most widely used parameter for clinical decision-making, but reproducibility and accuracy problems remain. We evaluated the usefulness of a novel training program based on cardiac magnetic resonance (CMR)...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-019-0173-z
更新日期:2019-10-31 00:00:00
abstract:BACKGROUND:Myocardial contractility can be investigated using longitudinal peak strain. It can be calculated using the Doppler-derived TDI method and the non-Doppler method based on tissue tracking on B-mode images. Both are validated and show good reproducibility, but no comparative analysis of their results has yet b...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-5-7
更新日期:2007-02-07 00:00:00
abstract:BACKGROUND:There is strong evidence that left atrial (LA) size is a prognostic marker in a variety of heart diseases. Recently, real-time three-dimensional echocardiography (RT3DE) has been reported as a useful tool for studying the phasic changes of the left atrial volumes. The aim of this study was to investigate the...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-9-38
更新日期:2011-11-24 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus (HIV) infection and antiretroviral treatment are associated with metabolic and cardiovascular complications that potentially increase the risk of atherosclerosis and cardiovascular disease in this population. Measurement of arterial wall thickness has been used as a surrogate of ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-9-9
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Dual imaging stress echocardiography, combining the evaluation of wall motion and coronary flow reserve (CFR) on the left anterior descending artery (LAD), and computed tomography coronary angiography (CTCA) are established techniques for assessing prognosis in chest pain patients. In this study we compared ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-015-0013-8
更新日期:2015-04-21 00:00:00
abstract::In this case report we describe a rare case of right atrium myxoma that coexisted with antiphospholipid syndrome in a young woman. We describe the unusual findings and diagnostic challenges combined with a review of the literature. ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-7-47
更新日期:2009-10-11 00:00:00
abstract:BACKGROUND:We hypothesized that longitudinal pulmonary arterial deformation during the cardiac cycle reflects pulmonary arterial capacitance. To examine this hypothesis, we assessed whether tissue Doppler-derived pulmonary annular motion could serve as a novel way to evaluate pulmonary arterial capacitance in pediatric...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-016-0081-4
更新日期:2016-09-07 00:00:00
abstract:BACKGROUND:Blood flow between the right and left ventricles is subject to the continuity equation and systolic ventricular interdependence. Quantification of this relationship might aid in understanding inter-ventricular function. The purpose of this study was to evaluate and quantify ventricular interdependence by dir...
journal_title:Cardiovascular ultrasound
pub_type: 临床试验,杂志文章
doi:10.1186/1476-7120-9-42
更新日期:2011-12-20 00:00:00
abstract:BACKGROUND:Transthoracic echocardiography (TTE) may be used for direct inspection of various parts of the main coronary arteries for detection of coronary stenoses and occlusions. We aimed to assess the feasibility of TTE to visualise the complete segments of the left main (LM), left descending (LAD), circumflex (Cx) a...
journal_title:Cardiovascular ultrasound
pub_type: 临床试验,杂志文章
doi:10.1186/1476-7120-7-58
更新日期:2009-12-22 00:00:00
abstract:PURPOSE:Left ventricular (LV) wall thickness can be measured at the posterior wall (PW) and the intraventricular septum (IVS) in a parasternal long axis view by transthoracic echocardiography. Thus, there are three methods to calculate relative wall thickness as follows: RWTPW = 2 × PWth/LVDd; RWTIVS + PW = (IVSth + PW...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-019-0179-6
更新日期:2019-12-03 00:00:00
abstract:BACKGROUND:The association of a Classical left bundle branch block (LBBB) contraction pattern and better outcome after cardiac resynchronization therapy (CRT) has only been studied using vendor-specific software for echocardiographic speckle-tracked longitudinal strain analysis. The purpose of this study was to assess ...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/s12947-019-0160-4
更新日期:2019-05-21 00:00:00
abstract:BACKGROUND:We investigated longitudinal right ventricular (RV) function assessed using speckle-tracking strain echocardiography in patient with myocardial infarction (MI), and identified the contributing factors for RV dysfunction. METHODS:We retrospectively studied 71 patients with old MI (the OMI group) and 45 norma...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-11-23
更新日期:2013-06-27 00:00:00
abstract:BACKGROUND:Although echocardiography has been incorporated into the diagnostic algorithm of patients with suspected infective endocarditis (IE), systematic usage in clinical practice remains ill defined. To determine the diagnostic accuracy of detecting vegetations using harmonic transthoracic echocardiography (hTTE) a...
journal_title:Cardiovascular ultrasound
pub_type: 杂志文章
doi:10.1186/1476-7120-5-20
更新日期:2007-05-19 00:00:00