Left Ventricular global longitudinal strain predicts heart failure readmission in acute decompensated heart failure.

Abstract:

BACKGROUND:The goal of this study was to determine if left ventricular (LV) global longitudinal strain (GLS) predicts heart failure (HF) readmission in patients with acute decompensated heart failure. METHODS AND RESULTS:Two hundred ninety one patients were enrolled at the time of admission for acute decompensated heart failure between January 2011 and September 2013. Left ventricle global longitudinal strain (LV GLS) by velocity vector imaging averaged from 2, 3 and 4-chamber views could be assessed in 204 out of 291 (70%) patients. Mean age was 63.8 ± 15.2 years, 42% of the patients were males and 78% were African American or Hispanic. Patients were followed until the first HF hospital readmission up to 44 months. Patients were grouped into quartiles on the basis of LV GLS. Kaplan-Meier curves showed significantly higher readmission rates in patients with worse LV GLS (log-rank p < 0.001). After adjusting for age, sex, history of ischemic heart disease, dementia, New York Heart Association class, LV ejection fraction, use of angiotensin converting enzyme inhibitors or angiotensin receptor blockers, systolic and diastolic blood pressure on admission and sodium level on admission, worse LV GLS was the strongest predictor of recurrent HF readmission (p < 0.001). The ejection fraction was predictive of readmission in univariate, but not in multivariate analysis. CONCLUSION:LV GLS is an independent predictor of HF readmission after acute decompensated heart failure with a higher risk of readmission in case of progressive worsening of LV GLS, independent of the ejection fraction.

journal_name

Cardiovasc Ultrasound

authors

Romano S,Mansour IN,Kansal M,Gheith H,Dowdy Z,Dickens CA,Buto-Colletti C,Chae JM,Saleh HH,Stamos TD

doi

10.1186/s12947-017-0098-3

subject

Has Abstract

pub_date

2017-03-15 00:00:00

pages

6

issue

1

issn

1476-7120

pii

10.1186/s12947-017-0098-3

journal_volume

15

pub_type

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