Quantification of cerebrospinal fluid ferritin as a biomarker for CNS malignant infiltration.


:Several markers have been studied for their ability to make the CNS infiltration diagnosis earlier and more precise; previous studies showed that CSF ferritin concentrations were higher in patients with malignant invasion of CNS. The objective was to determine the importance of CSF ferritin as a biomarker for the diagnosis of CNS neoplastic infiltration. This study is based on 93 CSF samples, divided into five groups: malignant cells present (n13); malignant cells not present (n26); inflammatory neurological diseases (n16); neurocysticercosis (n20); acute bacterial meningitis (n18). CSF ferritin values were determined by micro particle enzyme immunoassay. CSF ferritin level (mean+/-SD) in the group with neoplastic cells in the CSF was 42.8+/-49.7 ng/mL, higher than in the other groups (p<0.0001). We conclude that CSF ferritin with the cut off 20 ng/mL could be an adjuvant biomarker to the diagnosis of CNS malignant infiltration.


Arq Neuropsiquiatr


Almeida SM,Cunha DS,Yamada E,Doi EM,Ono M




Has Abstract


2008-09-01 00:00:00














  • [Effect of barbexaclone in convulsive crisis difficult to control].

    abstract::A therapeutic trial using barbexaclone in uncontrolled seizures was undertaken showing favourable results. Special reference to the association of barbexaclone with acetazolamide with good results in many cases is made. Collateral effects are minimal in pacients using barbexaclone. ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 临床试验,杂志文章


    authors: de Lima JM,Oliveira C,Duro LA,Poiares Nde M

    更新日期:1980-03-01 00:00:00

  • [Dermatopolymyositis: evaluation of 63 patients].

    abstract::Sixty-three patients with dermatopolymyositis were evaluated from the clinical, laboratory and therapeutical aspects during a period of 15 years: 39 are women and 24 men. The mean age was 36.8 +/- 15.6 years. No correlation was observed between clinical and isolated therapeutics employed; when corticosteroids and cyto...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Marchiori PE,Hirata MT,Scaff M,de Oliveira RM,Cossermelli W,Levy JA,de Assis JL

    更新日期:1987-06-01 00:00:00

  • Using clinical data to predict sleep hypoxemia in patients with acromegaly.

    abstract::Hypoxemia secondary to sleep apnea is commonly seen in patients with acromegaly, and this alteration apparently leads to considerable morbidity and mortality among such patients. With the objective of identifying hypoxemia based on clinical data, we conducted a cross-sectional study of 34 patients with acromegaly, all...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Rodrigues MP,Naves LA,Casulari LA,Silva CA,Araújo RR,Viegas CA

    更新日期:2007-06-01 00:00:00

  • Fluency in Parkinson's disease: disease duration, cognitive status and age.

    abstract::The objective of this study was to determine the frequency of occurrence and to characterize the typology of dysfluencies in individuals with Parkinson's disease (PD), including the variables age, gender, schooling, disease duration, score on the Hoehn and Yahr scale and cognitive status (score on Mini-Mental State Ex...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Brabo NC,Minett TS,Ortiz KZ

    更新日期:2014-05-01 00:00:00

  • [Myotonic dystrophy: study of clinico-genetic correlation in a pair of relatives (father-son)].

    abstract::We report the case of a child with myotonic dystrophy (DM) with symptoms beginning at the age of seven, whose genetic study showed an additional DNA fragment, greater than of his father, an asymptomatic carrier. The clinical and molecular analysis of this parent-child pair are probably the first described in Brazil, s...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Reed UC,Passos-Bueno MR,Nagahashi-Marie SK,Cerqueira A,Mendonça LI,Levy JA,Diament A,Zatz M

    更新日期:1994-12-01 00:00:00

  • Analysis of the albumin level, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio in Guillain-Barré syndrome.

    abstract::The purpose of this study was to investigate the prognostic value of the pretreatment and post-treatment albumin level, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) in subtypes of Guillain-Barré syndrome (GBS). A retrospective analysis of 62 patients with GBS treated between 2011 and 2015 in ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Ozdemir HH

    更新日期:2016-09-01 00:00:00

  • [Association of neuromotor retardation and chromosome lqH report of a case].

    abstract::A case of neuromotor retardation in association with chromosome 1qh's reported. Chromosomes analysis of the patient and three relatives showed increased long arm on the n. degrees 1 chromosome, in all of them. However it is wmphasized that the clinical feautre could be secondary to various non genetics factors, also. ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Jorge SM,Ribeiro VM,Ferrari I,Moreira LM

    更新日期:1976-12-01 00:00:00

  • Epileptiform abnormalities and quantitative EEG in children with attention-deficit/hyperactivity disorder.

    abstract::There is much controversy about the importance of the electroencephalogram (EEG) in assessing the attention-deficit/hyperactivity disorder (ADHD). The objective of this study was to assess the use of EEG and quantitative EEG (qEEG) in ADHD children. Thirty ADHD children and 30 sex- and age-matched controls with no neu...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Fonseca LC,Tedrus GM,Moraes Cd,Vicente Machado Ad,Almeida MP,Oliveira DO

    更新日期:2008-09-01 00:00:00

  • Vascular parkinsonism: a case series of 17 patients.

    abstract:OBJECTIVE:To report the clinical and neuroimaging findings in a case series of vascular parkinsonism (VP). METHODS:Seventeen patients with VP were evaluated with motor, cognitive, and neuroimaging standardized tests and scales. RESULTS:All patients had arterial hypertension. Ten patients were male and the mean age of...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Vale TC,Caramelli P,Cardoso F

    更新日期:2013-10-01 00:00:00

  • EEG alpha peak frequency analysis during memorizing of figures in patients with mild cognitive impairment.

    abstract:OBJECTIVE:To investigate spectral analysis of electroencephalograms (EEG) for the alpha frequency band during rest and cognitive stimulation in healthy adults and individuals with mild cognitive impairment. METHOD:We analyzed 56 EEGs from 28 patients, 7 men and 21 women, 12 of whom (40%) were controls, 16 patients wit...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Schmidt MT,Anghinah R,Basile LF,Forlenza O,Gattaz WF

    更新日期:2009-06-01 00:00:00

  • [Acquired immunodeficiency syndrome: analysis of neurologic complications in 44 cases].

    abstract::We studied the clinical records of 280 patients admitted to our Hospital between 1985 and 1988, with a positive Elisa test for HIV-related antibodies: 15.71% (44) of these patients exhibited clinical abnormalities related to disease of the CNS. In 6 (13.6%) patients the neurological complication was the first manifest...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Puccioni M,Favoreto AC,André C,Peixoto CA,Novis SA

    更新日期:1989-12-01 00:00:00

  • In the land of giants: the legacy of José Dantas de Souza Leite.

    abstract::The authors describe the extraordinary contribution to science made by José Dantas de Souza Leite, who graduated from the Bahia School of Medicine and trained in Prof. Charcot's Neurology Service under the supervision of Charcot's most able pupil, Dr. Pierre Marie. Souza Leite presented his doctoral thesis on acromega...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 传,历史文章,杂志文章


    authors: Teive HA,Lima PM,Germiniani FM,Boguszewski CL

    更新日期:2015-07-01 00:00:00

  • Surgical treatment of refractory epilepsy associated with space occupying lesions. Experience and review.

    abstract::Surgery for space occupying lesions of the brain associated with intractable epilepsy represents a special problem because relief of the epilepsy in as much an operative goal as excision of the space occupying lesion itself. This study concerns 32 patients with space occupying lesions and intractable epilepsy who unde...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,评审


    authors: Brainer-Lima PT,Rao S,Cukiert A,Yacubian EM,Gronich G,Marino Júnior R

    更新日期:1996-09-01 00:00:00

  • Traditional biomarkers in narcolepsy: experience of a Brazilian sleep centre.

    abstract:UNLABELLED:This study was thought to characterized clinical and laboratory findings of a narcoleptic patients in an out patients unit at São Paulo, Brazil. METHOD:28 patients underwent polysomnographic recordings (PSG) and Multiple Sleep Latency Test (MSLT) were analyzed according to standard criteria. The analysis of...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Coelho FM,Pradella-Hallinan M,Pedrazzoli M,Soares CA,Fernandes GB,Gonçalves AL,Tufik S,Bittencourt LR

    更新日期:2010-10-01 00:00:00

  • Désiré-Magloire Bourneville and his contributions to pediatric neurology.

    abstract::Désiré-Magloire Bourneville ought to be thought of as the father of Pediatric Neurology for his significant contributions to the field. He worked as a physician, politician, writer, and editor. He was the first to describe the autosomal dominant genetic condition known as "tuberous sclerosis complex", after conducting...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 传,历史文章,杂志文章


    authors: Gómez-López MT,Palacios-Sánchez L,Meerbeke AVV,Botero-Meneses JS

    更新日期:2019-05-13 00:00:00

  • Rosalie: the Brazilian female monkey of Charcot.

    abstract::Jean-Martin Charcot, the father of Neurology, a very austere and reserved man that did not express affection freely for human being, had a profound affection to animals, particularly to a small female monkey, called "Rosalie", which came from Brazil and was a gift of Dom Pedro II to Charcot. ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 传,历史文章,杂志文章


    authors: Teive HA,Arruda WO,Werneck LC

    更新日期:2005-09-01 00:00:00

  • Primary intracerebral and subarachnoid hemorrhage. An approach to diagnosis and therapy.

    abstract::The diagnosis of primary intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) has become easier with the advent of modern imaging techniques. The incidence of ICH has declined, while SAH has remained relatively constant. The prognosis for both disorders remains dismal and the mortality rate is substantiall...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,评审


    authors: Fisher M

    更新日期:1991-09-01 00:00:00

  • Exposure to pesticides and heterozygote genotype of GSTP1-Alw26I are associated to Parkinson's disease.

    abstract:OBJECTIVE:This study aimed to analyze the frequency of GSTP1-Alw26I polymorphism and to estimate its association with toxic substances in Parkinson's disease (PD). METHODS:A study group with 154 patients - subdivided into familial and sporadic PD groups - and 158 elderly individuals without the disease (control group)...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Longo GS,Pinhel MS,Sado CL,Gregório ML,Amorim GS,Florim GS,Mazeti CM,Martins DP,Oliveira FN,Tognola WA,Nakazone MA,Souza DR

    更新日期:2013-07-01 00:00:00

  • [Percutaneous vertebroplasty: option of treatment for osteoporotic vertebral fracture].

    abstract::Percutaneous vertebroplasty (PV) is a minimally invasive procedure used to treat focal pain from compressive vertebral fracture. The PV is indicated for the treatment of debilitating vertebral pain from osteoporotic vertebral fractures, metastatic disease (osteolytic), myeloma and hemagioma. We analyzed the results of...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Figueiredo N,Amaral Filho JC,Serra Ada R,Nogueira AM,Garcia VC,Weissheimer FL

    更新日期:2003-09-01 00:00:00

  • Evaluation of ubiquitin C-terminal hydrolase-L1 enzyme levels in patients with epilepsy.

    abstract:OBJECTIVE:Ubiquitin C-terminal Hydrolase-L1 (UCH-L1) enzyme levels were investigated in patients with epilepsy, epileptic seizure, remission period, and healthy individuals. METHODS:Three main groups were evaluated, including epileptic seizure, patients with epilepsy in the non-seizure period, and healthy volunteers. ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Yasak IH,Yilmaz M,GÖnen M,Atescelik M,Gurger M,Ilhan N,Goktekin MC

    更新日期:2020-07-01 00:00:00

  • Association between cognitive function and parameters of echocardiography and coronary artery angiography.

    abstract::We aimed to determine whether there is an association between cognition and the results of echocardiography and angiography, based on neuropsychological assessments. METHODS:We assessed the cognition of 85 patients who had recently undergone coronary artery angiography. We calculated the Gensini score for the coronar...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Hashemi M,Jervekani ZT,Mortazavi S,Maracy MR,Barekatain M

    更新日期:2018-04-01 00:00:00

  • [Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study].

    abstract:UNLABELLED:The P300 component of the event-related potential (ERP) is a general measurement of "cognitive efficiency". It is an index of the ability of an individual's central nervous system (CNS) to process incoming information. OBJECTIVE:To compare the neuromodulatory effects of caffeine and bromazepam on the visual...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,随机对照试验


    authors: Montenegro M,Veiga H,Deslandes A,Cagy M,McDowell K,Pompeu F,Piedade R,Ribeiro P

    更新日期:2005-06-01 00:00:00

  • Cortical projection of the inferior choroidal point as a reliable landmark to place the corticectomy and reach the temporal horn through a middle temporal gyrus approach.

    abstract:OBJECTIVE:To establish preoperatively the localization of the cortical projection of the inferior choroidal point (ICP) and use it as a reliable landmark when approaching the temporal horn through a middle temporal gyrus access. To review relevant anatomical features regarding selective amigdalohippocampectomy (AH) for...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Frigeri T,Rhoton A,Paglioli E,Azambuja N

    更新日期:2014-10-01 00:00:00

  • [Excessive daytime sleepiness, central type sleep apnea and myotonic dystrophy].

    abstract::Two cases of myotonic dystrophy with excessive daytime somnolence are described. All-night polysomnographic studies were performed revealing high number of central sleep apnea which triggered micro-arousals and awakenings leading to decrease of sleep efficiency as well as of stage 3, 4 and REM. Obstructive and mixed a...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Reimão R,Lemmi H,Bertorini T

    更新日期:1985-12-01 00:00:00

  • Clinical and epidemiological profile of patients diagnosed with multiple sclerosis in João Pessoa, Paraíba, Brazil.

    abstract::Prevalence rates of multiple sclerosis (MS) suggest an interrelationship between genetic and environmental factors, ranging worldwide.Objectives Clinical and epidemiological characterization of MS patients in João Pessoa, Paraíba city.Methods Study involving patients treated in five services in the city.Results It inc...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Negreiros AA,Sousa-Munõz RL,Oliveira BE,Nóbrega PV,Monteiro LL

    更新日期:2015-09-01 00:00:00

  • [Semantic dementia: clinical and neuroimaging evaluation. Case report].

    abstract::Semantic dementia is a clinical syndrome in the spectrum of frontotemporal lobar degeneration group. We report on a 63 years old man who presented with memory disorder of semantic nature for visual and mainly verbal material when he was 57 years old. Mild behavior impairment was present and related to exaggerated resp...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Caixeta L,Mansur LL

    更新日期:2005-06-01 00:00:00

  • Basal encephalocele associated with morning glory syndrome: case report.

    abstract::The basal encephaloceles refer to rare entities and they correspond to herniation of brain tissue through defects of skull along the cribiform plate or the sphenoid bone. A rare morning glory syndrome, with characteristic retinal defect has been reported in association with basal encephaloceles. Hypophysis hormonal de...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Minotto I,Abdala N,Miachon AA,Spinola e Castro AM,Imamura P,Nogueira RG

    更新日期:2007-12-01 00:00:00

  • An update in the management of spinal metastases.

    abstract::The best clinical treatment for spinal metastases requires an integrated approach with input from an interdisciplinary cancer team. The principle goals of treatment are maintenance or improvement in neurologic function and ambulation, spinal stability, durable tumor control, and pain relief. The past decade has witnes...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,评审


    authors: Joaquim AF,Powers A,Laufer I,Bilsky MH

    更新日期:2015-09-01 00:00:00

  • [Possible etiologies of West syndrome: evaluation of 95 patients].

    abstract:OBJECTIVE:To describe the etiologies of West syndrome (WS) among children followed in a rehabilitation center. METHOD:Retrospective study with emphasis in the following items: gender, age at the diagnosis of WS and its etiology. The etiologies were divided into three categories: symptomatic, cryptogenic and idiopathic...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Matta AP,Chiacchio SV,Leyser M

    更新日期:2007-09-01 00:00:00

  • Pyridoxine-dependent epilepsy initially responsive to phenobarbital.

    abstract::Pyridoxine-dependent epilepsy is a rare autosomal recessive disorder characterized by recurrent seizures that are not controlled by anticonvulsant medications but remits after administration of pyridoxine. We report on a 30 day-old girl who presented with seizures during the first day of life, initially responsive to ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Lin J,Lin K,Masruha MR,Vilanova LC

    更新日期:2007-12-01 00:00:00