Update on oral cyanocobalamin (vitamin B12) treatment in elderly patients.

Abstract:

:The objective of this review is to evaluate the usefulness of oral cobalamin (vitamin B12) treatment in elderly patients. PubMed was systematically searched for English and French articles published from January 1990 to January 2007. Prospective randomized studies (n=3), a systematic review by the Cochrane group (n=1) and prospective studies in a well defined population (n=5) provide evidence that oral cobalamin therapy may adequately treat cobalamin deficiency in elderly patients. However, the current literature does not suggest a strategy in terms of the form (hydroxy- or cyanocobalamin), frequency and duration of the treatment. This review confirms the previously reported efficacy of oral cobalamin treatment in elderly patients. Oral cobalamin treatment avoids the discomfort, inconvenience and cost of monthly injections.

journal_name

Drugs Aging

journal_title

Drugs & aging

authors

Andrès E,Vogel T,Federici L,Zimmer J,Kaltenbach G

doi

10.2165/0002512-200825110-00003

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

927-32

issue

11

eissn

1170-229X

issn

1179-1969

pii

25113

journal_volume

25

pub_type

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