Value of regional wall motion abnormality in the emergency room diagnosis of acute myocardial infarction. A prospective study using two-dimensional echocardiography.

abstract：BACKGROUND:It is not known whether subspecialty care by cardiologists improves outcomes in heart failure patients from the community over care by other physicians. METHODS AND RESULTS:Using administrative data, we monitored 38 702 consecutive patients with first-time hospitalization for heart failure in Ontario, Canad...

journal_title：Circulation

authors： Jong P,Gong Y,Liu PP,Austin PC,Lee DS,Tu JV

更新日期：2003-07-15 00:00:00

abstract：:One hundred consecutive men with a normal ECG at rest had a maximal treadmill test using 14 leads during and post-exercise. Coronary arteriography performed the following day revealed coronary stenoses greater than or equal to 70% in 66 patients. Test results obtained from a V5 lead were compared to different lead com...

journal_title：Circulation

authors： Chaitman BR,Bourassa MG,Wagniart P,Corbara F,Ferguson RJ

更新日期：1978-01-01 00:00:00

abstract：:In our approach to dynamic cardiomyoplasty, which consists of wrapping a skeletal muscle around the heart and stimulating the former in synchrony with heart contractions to augment ventricular contractility, we have transferred a latissimus dorsi muscle flap to the heart by way of a partial resection of the second rib...

journal_title：Circulation

authors： Chachques JC,Grandjean P,Schwartz K,Mihaileanu S,Fardeau M,Swynghedauw B,Fontaliran F,Romero N,Wisnewsky C,Perier P

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Ten percent to 20% of potential cardiac donors with brain injury and no previous cardiac history have myocardial dysfunction. We assessed components of the beta-receptor-G-protein-adenylyl cyclase complex as well as the contractile response in 10 explanted acutely failing human hearts (donor heart dysfunctio...

journal_title：Circulation

authors： White M,Wiechmann RJ,Roden RL,Hagan MB,Wollmering MM,Port JD,Hammond E,Abraham WT,Wolfel EE,Lindenfeld J

更新日期：1995-10-15 00:00:00

abstract：BACKGROUND:It is not clear why some plaque ruptures lead to acute coronary syndromes (ACS) but others do not. METHODS AND RESULTS:We analyzed 80 plaque ruptures in 74 patients and compared culprit lesions of ACS patients with nonculprit lesions of ACS patients and lesions of non-ACS patients; both culprit and nonculpr...

journal_title：Circulation

authors： Fujii K,Kobayashi Y,Mintz GS,Takebayashi H,Dangas G,Moussa I,Mehran R,Lansky AJ,Kreps E,Collins M,Colombo A,Stone GW,Leon MB,Moses JW

更新日期：2003-11-18 00:00:00

abstract：:Plasma and lipoprotein cholesterol and triglyceride concentrations were measured in Pima Indians, a genetically homogeneous population with a high prevalence of obesity and diabetes and a low frequency of coronary heart disease. The data for nondiabetic Pima Indians were compared with those of U.S. Caucasians measured...

journal_title：Circulation

authors： Howard BV,Davis MP,Pettitt DJ,Knowler WC,Bennett PH

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:After repair of aortic coarctation, patients may develop restenosis, aneurysms, and pseudoaneurysms at the site of prior repair. We assessed the outcomes of late reintervention on the descending aorta after aortic coarctation repair. METHODS AND RESULTS:From March 1954 to July 2008, 130 patients had operati...

journal_title：Circulation

authors： Brown ML,Burkhart HM,Connolly HM,Dearani JA,Hagler DJ,Schaff HV

更新日期：2010-09-14 00:00:00

abstract：BACKGROUND:Although aspirin is an effective, inexpensive, and safe treatment of acute myocardial infarction, the frequency of use of aspirin in actual medical practice is not known. Elderly patients, a group with low rates of utilization of effective therapies such as thrombolytic therapy, also may be at risk of not re...

journal_title：Circulation

authors： Krumholz HM,Radford MJ,Ellerbeck EF,Hennen J,Meehan TP,Petrillo M,Wang Y,Kresowik TF,Jencks SF

更新日期：1995-11-15 00:00:00

abstract：BACKGROUND:Recently, it was reported that the degree of microvascular injury and left ventricular functional recovery during the chronic period can be predicted after treatment of the infarct-related artery based on the coronary flow velocity (CFV) pattern assessed using a Doppler guidewire. The aim of this prospective...

journal_title：Circulation

authors： Yamamuro A,Akasaka T,Tamita K,Yamabe K,Katayama M,Takagi T,Morioka S

更新日期：2002-12-10 00:00:00

abstract：BACKGROUND:Approximately half of all patients with chronic heart failure (HF) have a decreased ejection fraction (EF) (systolic HF [SHF]); the other half have HF with a normal EF (diastolic HF [DHF]). However, the underlying pathophysiological differences between DHF and SHF patients are incompletely defined. The purpo...

journal_title：Circulation

authors： Zile MR,Bennett TD,St John Sutton M,Cho YK,Adamson PB,Aaron MF,Aranda JM Jr,Abraham WT,Smart FW,Stevenson LW,Kueffer FJ,Bourge RC

更新日期：2008-09-30 00:00:00

abstract：:In the United States each year, >5.3 million patients present to emergency departments with chest discomfort and related symptoms. Ultimately, >1.4 million individuals are hospitalized for unstable angina and non-ST-segment elevation myocardial infarction. For emergency physicians and cardiologists alike, these patien...

journal_title：Circulation

authors： Gibler WB,Cannon CP,Blomkalns AL,Char DM,Drew BJ,Hollander JE,Jaffe AS,Jesse RL,Newby LK,Ohman EM,Peterson ED,Pollack CV,American Heart Association Council on Clinical Cardiology (Subcommittee on Acute Cardiac Care).,Council on

更新日期：2005-05-24 00:00:00

abstract：:Recent studies have shown that blood flow during closed-chest cardiopulmonary resuscitation (CPR) results primarily from generalized changes in intrathoracic pressure rather than direct compression of the heart. Since ascending aortic and right atrial pressures rise and fall synchronously and to comparable levels duri...

journal_title：Circulation

authors： Ditchey RV,Winkler JV,Rhodes CA

更新日期：1982-08-01 00:00:00

abstract：:The echographic isovolumic contraction time (ICT) of the left ventricle (LV) was measured in order to assess alterations of LV performance in children with various forms of cardiac disease. The echographic ICT was defined as the interval between coaptation of the anterior and posterior mitral valve leaflets and aortic...

journal_title：Circulation

authors： Hirschfeld S,Meyer R,Korfhagen J,Kaplan S,Liebman J

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Pregnant women with congenital heart disease (CHD) are susceptible to cardiovascular, obstetric, and offspring complications. In women with CHD, cardiac dysfunction may compromise uteroplacental flow and contribute to the increased incidence of obstetric and offspring events. METHODS AND RESULTS:We performe...

journal_title：Circulation

authors： Pieper PG,Balci A,Aarnoudse JG,Kampman MA,Sollie KM,Groen H,Mulder BJ,Oudijk MA,Roos-Hesselink JW,Cornette J,van Dijk AP,Spaanderman ME,Drenthen W,van Veldhuisen DJ,ZAHARA II investigators.

更新日期：2013-12-03 00:00:00

abstract：BACKGROUND:Mechanisms by which neutrophils are attracted to the myocardium in ischemia/reperfusion are not fully defined. Lipopolysaccharide-induced CXC chemokine (LIX), cytokine-induced neutrophil chemoattractant (KC), and macrophage inflammatory protein-2 (MIP-2) are rodent chemokines with potent neutrophil-chemotact...

journal_title：Circulation

authors： Chandrasekar B,Smith JB,Freeman GL

更新日期：2001-05-08 00:00:00

abstract：BACKGROUND:Present therapies for acute coronary syndromes aim toward limiting platelet-platelet adhesion and aggregation processes. However, platelet-leukocyte interactions may contribute importantly to disease progression in the arterial wall. Recent studies suggest that prevention of platelet-leukocyte binding via P-...

journal_title：Circulation

authors： Sarma J,Laan CA,Alam S,Jha A,Fox KA,Dransfield I

更新日期：2002-05-07 00:00:00

abstract：BACKGROUND:Experimental studies suggest that arterial injury and inflammation lead to increased neointimal growth after stenting. Despite the increased use of coronary stents in humans, there are only limited pathological data on the morphological features of in-stent restenosis. METHODS AND RESULTS:Detailed histology...

journal_title：Circulation

authors： Farb A,Weber DK,Kolodgie FD,Burke AP,Virmani R

更新日期：2002-06-25 00:00:00

abstract：BACKGROUND:Premedication with clopidogrel has reduced thrombotic complications after percutaneous coronary revascularization procedures. However, because of the enhanced and irreversible platelet inhibition by clopidogrel, patients requiring surgical revascularization have a higher risk of bleeding complications and tr...

journal_title：Circulation

authors： Kapetanakis EI,Medlam DA,Petro KR,Haile E,Hill PC,Dullum MK,Bafi AS,Boyce SW,Corso PJ

更新日期：2006-04-04 00:00:00

abstract：:The specific and sensitivity of serum creatine phosphokinase cardiac specific isoenzyme (MB) in the diagnosis of acute myocardial infarction (AMI) was evaluated. An ion-exchange chromatographic technique was used to isolate MB. Sera layered on mini-columns of DEAE-Sephadex were eluted with Tris-buffered sodium chlorid...

journal_title：Circulation

authors： Varat MA,Mercer DW

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Preclinical systolic or diastolic dysfunction is associated with increased morbidity and mortality. We postulated that plasma brain natriuretic peptide (BNP) might serve as a biomarker for preclinical ventricular dysfunction (PCVD) but that the discriminatory values for BNP may vary with age and sex. METHOD...

journal_title：Circulation

authors： Redfield MM,Rodeheffer RJ,Jacobsen SJ,Mahoney DW,Bailey KR,Burnett JC Jr

更新日期：2004-06-29 00:00:00

abstract：BACKGROUND:Several of the theories on the pathogenesis of atherosclerosis may be integrated into a single multifactorial one. According to this theory, the most likely sequence of events involved in early atherosclerosis is vascular dysfunction and/or injury, monocyte recruitment and macrophage formation, lipid deposit...

journal_title：Circulation

authors： Badimon JJ,Fuster V,Chesebro JH,Badimon L

更新日期：1993-03-01 00:00:00

abstract：:To investigate whether a fixed external reference system should be used to most accurately describe regional left ventricular wall motion, we used vectors to analyze a simple model of ventricular contraction. If measured in a fixed external reference system, motion of implanted radiopaque midwall markers may contain t...

journal_title：Circulation

authors： Clayton PD,Jeppson GM,Klausner SC

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Serum uric acid (UA) could be a valid prognostic marker and useful for metabolic, hemodynamic, and functional (MFH) staging in chronic heart failure (CHF). METHODS AND RESULTS:For the derivation study, 112 patients with CHF (age 59+/-12 years, peak oxygen consumption [Vo2] 17+/-7 mL/kg per minute) were recr...

journal_title：Circulation

authors： Anker SD,Doehner W,Rauchhaus M,Sharma R,Francis D,Knosalla C,Davos CH,Cicoira M,Shamim W,Kemp M,Segal R,Osterziel KJ,Leyva F,Hetzer R,Ponikowski P,Coats AJ

更新日期：2003-04-22 00:00:00

abstract：BACKGROUND:Endogenous nitric oxide (NO) has been reported to inhibit oxygen consumption in the normal heart, so that nonselective inhibition of NO synthase (NOS) caused an increase of myocardial oxygen consumption (MVO2). Although endothelial NOS responses are depressed in congestive heart failure (CHF), inducible NOS ...

journal_title：Circulation

authors： Chen Y,Traverse JH,Du R,Hou M,Bache RJ

更新日期：2002-07-09 00:00:00

abstract：BACKGROUND:The risk of recurrent venous thrombosis is 2-fold higher in men than in women. In contrast, no such sex difference in the risk of first venous thrombosis has been reported. We hypothesized that, for a first event, a risk difference between the sexes is masked by female exposure to reproductive factors (oral ...

journal_title：Circulation

authors： Roach RE,Lijfering WM,Rosendaal FR,Cannegieter SC,le Cessie S

更新日期：2014-01-07 00:00:00

abstract：OBJECTIVES:To determine, using systematic review of the biomedical literature, whether pacing reduces risk of recurrent syncope and relevant clinical outcomes among adult patients with reflex-mediated syncope. METHODS:MEDLINE (through PubMed), EMBASE, and the Cochrane Central Register of Controlled Trials (through Oct...

journal_title：Circulation

authors： Varosy PD,Chen LY,Miller AL,Noseworthy PA,Slotwiner DJ,Thiruganasambandamoorthy V

更新日期：2017-08-01 00:00:00

abstract：:Mitochondria have emerged as a central factor in the pathogenesis and progression of heart failure, and other cardiovascular diseases, as well, but no therapies are available to treat mitochondrial dysfunction. The National Heart, Lung, and Blood Institute convened a group of leading experts in heart failure, cardiova...

journal_title：Circulation

authors： Tian R,Colucci WS,Arany Z,Bachschmid MM,Ballinger SW,Boudina S,Bruce JE,Busija DW,Dikalov S,Dorn GW II,Galis ZS,Gottlieb RA,Kelly DP,Kitsis RN,Kohr MJ,Levy D,Lewandowski ED,McClung JM,Mochly-Rosen D,O'Brien KD,O'R

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:A number of parameters reflecting the effects of idiopathic dilated cardiomyopathy (IDC) on the structure and function of myosin from the human myocardium were analyzed. METHODS AND RESULTS:The content of the regulatory light chain, LC2, was reduced in myopathic heart myosin in contrast to the controls in w...

journal_title：Circulation

authors： Margossian SS,White HD,Caulfield JB,Norton P,Taylor S,Slayter HS

更新日期：1992-05-01 00:00:00

abstract：:From November 1981 to November 1982, intra-aortic balloon pumping (IABP) was used after surgery in eight patients who were from 6 weeks to 6 years old and who weighed from 4.2 to 16.2 kg. In seven patients, specially constructed intra-aortic balloons with 2.5 and 5.0 ml volumes mounted on No. 5F catheters were used. I...

journal_title：Circulation

authors： Veasy LG,Blalock RC,Orth JL,Boucek MM

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Mitral regurgitation (MR) generally accompanies inferobasal myocardial infarction (MI), with leaflet tethering by displaced papillary muscles. Mitral regurgitation is also reported with anteroapical MI without global dilatation or inferior wall motion abnormalities. We hypothesized that anteroapical MI exten...

journal_title：Circulation

authors： Yosefy C,Beeri R,Guerrero JL,Vaturi M,Scherrer-Crosbie M,Handschumacher MD,Levine RA

更新日期：2011-04-12 00:00:00