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Anti-acetylcholine receptor antibodies decrease after thymectomy in patients with myasthenia gravis. Clinical correlations.

Abstract：

:Clinical course and changes in serum levels of antibodies to the acetylcholine receptor (a-AChR) were followed in 82 patients with myasthenia gravis during a period of 1-8 years after thymectomy. Decrease in a-AChR immediately after thymectomy was influenced by changes in a total IgG. Immunosuppressive medication affected serum a-AChR at all points of time. In a subgroup of 41 patients without thymoma who had no immunosuppressive drugs, there was a steady decrease in a-AChR concomitant with clinical improvement from 6 weeks after thymectomy.

journal_name

J Autoimmun

journal_title

Journal of autoimmunity

authors

Kuks JB,Oosterhuis HJ,Limburg PC,The TH

doi

10.1016/0896-8411(91)90018-8

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

197-211

issue

2

eissn

0896-8411

issn

1095-9157

pii

0896-8411(91)90018-8

journal_volume

4

pub_type

杂志文章

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