Abstract：
:We investigated whether children presenting with a first seizure experienced anxiety and depressive signs. Children (aged 7-17 years) with a first unprovoked afebrile seizure participated. These patients (mean age, 12 +/- 2.7 years S.D.; 14 female/8 male) completed the Revised Child Manifest Anxiety Scale (n = 22) and Children's Depression Inventory (n = 20). Scores were compared with: (1) published norms, and (2) control patients with new medical signs. Compared with the published norms, children reported greater total anxiety (P < 0.02), worry/oversensitivity (P < 0.008), and social concerns/concentration (P < 0.005). However, compared with the control patients, no difference was seen between groups. Total Children's Depression Inventory scores were higher than for published norms (P = 0.05) and control patients (P = 0.04). Children with a first seizure reported greater interpersonal problems (P < 0.01), ineffectiveness (P < 0.03), and negative self-esteem (P < 0.05) than published norms, and increased negative mood (P = 0.04), ineffectiveness (P = 0.04), anhedonia (P = 0.05), and negative self-esteem (P = 0.05) than control patients. Our results suggest that anxiety may be related to an illness or to the hospital experience itself, whereas depressive signs may be a comorbidity present at time of presentation of the first seizure. If a larger cohort substantiates these results, early screening for these signs would be of clinical importance.
journal_name
Pediatr Neuroljournal_title
Pediatric neurologyauthors
Loney JC,Wirrell EC,Sherman EM,Hamiwka LDdoi
10.1016/j.pediatrneurol.2008.07.005subject
Has Abstractpub_date
2008-10-01 00:00:00pages
236-40issue
4eissn
0887-8994issn
1873-5150pii
S0887-8994(08)00325-1journal_volume
39pub_type
杂志文章abstract：:A prospective study of the efficacy of seizure cessation by phenobarbital versus phenytoin administration utilized both clinical and electroencephalographic expressions of seizure behaviors. The phenomenon of uncoupling was defined as the persistence of electrographic seizures despite the suppression of >or=50% clinic...
journal_title：Pediatric neurology
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
pub_type： 杂志文章
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journal_title：Pediatric neurology
pub_type： 杂志文章
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更新日期：2010-08-01 00:00:00
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journal_title：Pediatric neurology
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更新日期：2009-11-01 00:00:00
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pub_type： 杂志文章
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更新日期：2006-08-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/0887-8994(86)90075-5
更新日期：1986-11-01 00:00:00
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journal_title：Pediatric neurology
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更新日期：1995-04-01 00:00:00
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journal_title：Pediatric neurology
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更新日期：2014-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：1992-11-01 00:00:00
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更新日期：2009-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-03-01 00:00:00
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
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更新日期：2010-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：2016-09-01 00:00:00
abstract：:The third case of cyclic vomiting syndrome with a large mitochondrial deoxyribonucleic acid rearrangement is described. Multiple neuromuscular anomalies are present that meet the diagnostic criteria for Kearns-Sayre syndrome, as well as severe symmetrical growth retardation. A 3-kilobase mitochondrial deoxyribonucleic...
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更新日期：2007-02-01 00:00:00
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