Abstract：
:Alexia without agraphia is a rare disconnection syndrome characterized by the loss of reading ability with retention of writing and verbal comprehension. We report a patient who developed alexia without agraphia after undergoing a biopsy for a malignant glioma involving the left thalamus. A 15-year-old right-handed male presented with 3 days of severe headache, and vomiting, and 1 month of blurry vision in his right visual field. Magnetic resonance imaging of the brain disclosed a large exophytic mass originating in the left thalamus, with mass effect and hydrocephalus. The patient underwent biopsy of the left thalamic mass via a transcallosal approach. Postoperatively, the patient complained of inability to read or identify letters. Examination revealed alexia without agraphia. The syndrome of alexia without agraphia can be rarely caused after surgery. A transcallosal procedure through the splenium of the corpus callosum may disrupt the visual association fibers traveling from the right occipital cortex to the left angular gyrus. In our case the syndrome occurred because of a preexisting right homonymous hemianopia resulting from a left thalamic tumor.
journal_name
Pediatr Neuroljournal_title
Pediatric neurologyauthors
Tamhankar MA,Coslett HB,Fisher MJ,Sutton LN,Liu GTdoi
10.1016/S0887-8994(03)00417-Xsubject
Has Abstractpub_date
2004-02-01 00:00:00pages
140-2issue
2eissn
0887-8994issn
1873-5150pii
S088789940300417Xjournal_volume
30pub_type
杂志文章abstract：:Serial examination of the cerebral hemispheres of 20 sudden infant death syndrome victims revealed high incidence of leukomalacia (40%), leptomeningeal glioneuronal heterotopias (70%) at the base of the cerebrum, and astrogliosis (65%) in the white matter and medulla reticular formation compared with 20 age-matched co...
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
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