Abstract:
PURPOSE:To evaluate with 1H-magnetic resonance spectroscopy (MRS) the metabolites rations of the foramen of Monro's region in patients with tuberous sclerosis complex (TSC). METHOD:Twelve patients with TSC and an age and gender-matched control group underwent MR imaging at a 1.5T scanner, and 1H-MRS at the foramen of Monro level with a multivoxel acquisition. Similar volumes of interest were selected in each side of the foramen of Monro and in the basal ganglia (lentiform nuclei). The obtained N-acetylaspartate (NAA), creatine (Cr) and choline (Cho) peak amplitude values and ratios were studied. The statistical analysis was performed and p<0.05 was considered statically significant. RESULTS:There was no significant difference between the NAA/Cr and Cho/Cr ratios near to the foramen of Monro and basal ganglia of the TSC patients compared with the controls (p>0.05). CONCLUSION:The NAA/Cr and Cho/Cr ratios near to the foramen of Monro and basal ganglia of TSC patients are similar to the rations obtained in the control group.
journal_name
Arq Neuropsiquiatrjournal_title
Arquivos de neuro-psiquiatriaauthors
Carvalho-Neto Ad,Bruck I,Antoniuk SA,Marchiori E,Gasparetto ELdoi
10.1590/s0004-282x2008000300003subject
Has Abstractpub_date
2008-06-01 00:00:00pages
303-7issue
2Beissn
0004-282Xissn
1678-4227pii
S0004-282X2008000300003journal_volume
66pub_type
杂志文章abstract:OBJECTIVE:To describe the clinical activities at the Neuroimmunology Clinic of the Universidade Federal de São Paulo (UNIFESP) from 1994 to 2013. METHOD:The final diagnosis of all patients that attended the center was reviewed and established upon specific guidelines for each disease. The number of total appointments ...
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