Endometrial effects of letrozole and clomiphene citrate in women with polycystic ovary syndrome using spiral artery Doppler.

Abstract:

OBJECTIVES:To compare the effects of letrozole and clomiphene citrate (CC) on endometrial response in PCOS using subendometrial spiral artery Doppler. METHODS:Fifty consecutive patients of anovulatory PCOS were recruited. Twenty-five patients (58 cycles) received 2.5-5 mg of letrozole; 25 patients (56 cycles) received 50-100 mg of CC (both orally on days 5-9 of menses). MAIN OUTCOME MEASURES:number of dominant follicles, endometrial thickness (ET), spiral artery resistance index (RI) and pulsatility index (PI) and pregnancy rate. RESULTS:The mean number of dominant follicles in letrozole group and CC groups was 1.63+/-1.02 and 1.62+/-0.96, respectively (P>0.05). The mean mid cycle ET was 6.9+/-0.74 mm in letrozole group and 5.9+/-0.53 mm in CC group (P<0.05). In letrozole and CC groups, the mean RI of spiral artery were 0.63+/-0.05 and 0.79+/-0.09, respectively, and the mean PI of spiral artery were 1.19+/-0.06 and 1.55+/-0.13, respectively. Both RI and PI in the letrozole group showed significant lower impedance compared to CC group (P<0.05). Pregnancy rate per cycle was 19% (11/58) in the letrozole group and 12.5% (7/56) in the CC group (P>0.05). CONCLUSION:The effect of letrozole showed a significantly better endometrial response compared to CC.

journal_name

Arch Gynecol Obstet

authors

Baruah J,Roy KK,Rahman SM,Kumar S,Sharma JB,Karmakar D

doi

10.1007/s00404-008-0714-4

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

311-4

issue

3

eissn

0932-0067

issn

1432-0711

journal_volume

279

pub_type

杂志文章,随机对照试验
  • Letrozole ovulation induction: an effective option in endometrial preparation for frozen-thawed embryo transfer.

    abstract:PURPOSE:To evaluate the clinical efficacy of letrozole on ovulation induction and hormone replacement therapy (HRT) during endometrial preparation for frozen-thawed embryo transfer (FET). METHODS:We analyzed totally 1,230 cycles of patients that underwent FET from October 2010 to September 2012. Seven hundred and thir...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-013-3044-0

    authors: Li SJ,Zhang YJ,Chai XS,Nie MF,Zhou YY,Chen JL,Tao GS

    更新日期:2014-03-01 00:00:00

  • Vaginal removal of prolapsed pedunculated submucous myoma: a short, simple, and definitive procedure with minimal morbidity.

    abstract:OBJECTIVE:Our objective was to evaluate the outcome of vaginal removal of prolapsed pedunculated submucous myomas over a 10-year period. STUDY DESIGN:Retrospective observational study. Fifty-two patients were admitted with the diagnosis of prolapsed pedunculated submucous myoma. Six patients were excluded because of a...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-003-0590-x

    authors: Golan A,Zachalka N,Lurie S,Sagiv R,Glezerman M

    更新日期:2005-01-01 00:00:00

  • Correction to: Breast cancer patients' satisfaction with individual therapy goals and treatment in a standardized integrative medicine consultancy service.

    abstract::In the original version of this article contained an error in figure 1. It was provided in German. ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s00404-018-4785-6

    authors: Hack CC,Antoniadis S,Hackl J,Langemann H,Schwitulla J,Fasching PA,Beckmann MW,Theuser AK

    更新日期:2018-07-01 00:00:00

  • Prophylactic mastectomy with immediate reconstruction combined with simultaneous laparoscopic salpingo-oophorectomy via a transmammary route: a novel surgical approach to female BRCA-mutation carriers.

    abstract:INTRODUCTION:Breast reconstruction with salpingo-oophorectomy can easily be performed in patients with genetic mutations increasing the risk for mammary and ovarian carcinoma. However, many patients are skeptical about having several surgeries, as they may result in additional anesthesiological risks as well as multipl...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-013-3133-0

    authors: Perabò M,Fink V,Günthner-Biller M,von Bodungen V,Friese K,Dian D

    更新日期:2014-06-01 00:00:00

  • Abdominopelvic tuberculosis mimicking advanced ovarian cancer and pelvic inflammatory disease: a series of 28 female cases.

    abstract:OBJECTIVE:To present and discuss 28 female cases with abdominopelvic tuberculosis (TB) and abnormal CA125 levels to better distinguish this disease from advanced ovarian cancer (AOC) and pelvic inflammatory disease (PID). Abdominopelvic tuberculosis (APTB) is one of the extrapulmonary tuberculosis (TB) sites, usually m...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-013-3034-2

    authors: Liu Q,Zhang Q,Guan Q,Xu JF,Shi QL

    更新日期:2014-03-01 00:00:00

  • Comparing the efficacy of intrauterine lidocaine and paracervical block in decreasing the pain associated with endometrial biopsy: a randomised trial.

    abstract:PURPOSE:Almost 50% of the patients experience moderate-to-severe pain during endometrial biopsy. The study aimed to examine the effectiveness of intrauterine lidocaine for relieving pain during endometrial biopsy. METHODS:A randomised trial was conducted in 120 patients undergoing endometrial biopsy. Sixty-seven women...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-013-3036-0

    authors: Cengiz H,Dağdeviren H,Kaya C,Yeşil A,Çaypınar SS

    更新日期:2014-03-01 00:00:00

  • Fentanyl HCl iontophoretic transdermal system versus intravenous morphine pump after gynecologic surgery.

    abstract:OBJECTIVE:To compare the efficacy and safety of fentanyl iontophoretic transdermal system (ITS) with morphine intravenous patient-controlled analgesia (IV PCA) for pain management following gynecologic surgery. METHOD:A subgroup (n = 275) of gynecologic surgery patients from a randomized study (N = 636) of patients tr...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00404-007-0339-z

    authors: Ahmad S,Hewitt DJ,Damaraju CV

    更新日期:2007-09-01 00:00:00

  • Appendiceal endometriosis presenting as perforated appendicitis: report of a case and review of the literature.

    abstract::While endometriosis is a common disorder in women of reproductive age, appendiceal endometriosis accounts for less than 1% of all pelvic endometriotic lesions. Involvement at this site may present as acute appendicitis and be diagnosed only upon postoperative histopathologic examination. We report such an occurrence o...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-008-0922-y

    authors: Akbulut S,Dursun P,Kocbiyik A,Harman A,Sevmis S

    更新日期:2009-09-01 00:00:00

  • Fibroadenoma of the vulva.

    abstract::A well-circumscribed mass was excised from the vulva of a 37-year-old woman. Histological and immunohistochemical findings showed the characteristic features of fibroadenoma of breast. The concepts about the histogenesis of this lesion were discussed. ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s004040050281

    authors: Güler G,Usubütün A,Küçükali T

    更新日期:2000-04-01 00:00:00

  • Amniotic fluid CA-125 as a marker of intra-amniotic inflammation associated with preterm delivery: a preliminary single center study.

    abstract:OBJECTIVE:The purpose of this study was to investigate whether amniotic fluid (AF) CA-125 in patients with preterm labor or preterm premature rupture of membranes can help predict intra-amniotic inflammation (IAI), microbial invasion of the amniotic cavity (MIAC) and imminent delivery. METHODS:We recruited 36 women wh...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-015-3775-1

    authors: Seong WJ

    更新日期:2016-01-01 00:00:00

  • Maternal mortality in southern Israel.

    abstract::Between 1969 and 1991 there were 166,410 births in Southern Israel with 13 maternal deaths (7.8/100,000). In the Jewish population there were 119,130 deliveries with 7 maternal deaths (5.9/100,000), and the Bedouins had 47,280 deliveries with 6 maternal deaths (12.7/100,000). Prenatal care was an important preventive ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/BF02426359

    authors: Leiberman JR,Fraser D,Mazor M,Glezerman M

    更新日期:1993-01-01 00:00:00

  • Is there a role for placental histopathology in predicting the recurrence of preterm birth?

    abstract:PURPOSE:Spontaneous preterm birth (sPTB) is a major cause of neonatal morbidity and mortality with a relatively high rate to recurrence. Our aim was to study the role of placental histopathology in predicting recurrence of sPTB. METHODS:We conducted a retrospective cohort study. The medical records and placental patho...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-019-05266-x

    authors: Mizrachi Y,Barber E,Torem M,Tairy D,Weiner E,Bar J,Schreiber L,Kovo M

    更新日期:2019-10-01 00:00:00

  • Prognostic significance of estrogen receptor alpha and beta expression in human serous carcinomas of the ovary.

    abstract:BACKGROUND:Ovarian cancer is a gynecologic cancer with a high mortality rate. This shows the need of effective screening methods and reliable cancer markers for ovarian cancer staging and appropriate effective cancer treatment. METHODS:Expression of estrogen receptor alpha and beta was studied by immunhistochemical an...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-009-1185-y

    authors: Burges A,Brüning A,Dannenmann C,Blankenstein T,Jeschke U,Shabani N,Friese K,Mylonas I

    更新日期:2010-03-01 00:00:00

  • Retained foetal bones: an intrauterine cause of chronic pelvic pain.

    abstract::Intrauterine retention of foetal bones is an uncommon but recognised complication of late termination of pregnancy. Secondary subfertility, abnormal uterine bleeding and vaginal discharge are the usual presenting complaints. We report a case of prolonged retention of foetal bones for 14 years in a woman who presented ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-008-0686-4

    authors: Kalu E,Richardson R

    更新日期:2009-02-01 00:00:00

  • Effectiveness of short-term maintenance treatment with cabergoline in microadenoma-related and idiopathic hyperprolactinemia.

    abstract:OBJECTIVE:This study aimed to determine the effectiveness of short-term maintenance treatment with cabergoline and to find out minimum effective dosage of cabergoline during maintenance treatment for patients with microadenoma-related and idiopathic hyperprolactinemia. STUDY DESIGN:Cabergoline was administered orally ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-010-1562-6

    authors: Buyukbayrak EE,Karageyim Karsidag AY,Kars B,Balcik O,Pirimoglu M,Unal O,Turan C

    更新日期:2010-11-01 00:00:00

  • Primary ovarian trabecular carcinoid tumor: a case report and literature review.

    abstract:INTRODUCTION:Carcinoid tumors are uncommon neoplasms in the diffuse peripheral endocrine system. Ovarian carcinoids are rare and can be primary or transplanted. Primary ovarian carcinoids make up approximately 0.5-1.7% of all carcinoid tumors. CASE REPORT:We describe the case of a 55-year-old female patient. A tumor i...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-010-1600-4

    authors: Bai X,Li N,Wang F,Li S,Yu Q

    更新日期:2010-10-01 00:00:00

  • The relation of pelvic pain and dense adhesions to Doppler ultrasound findings in patients with ovarian endometriomas.

    abstract:PURPOSE:To study the relation of pelvic pain symptoms and pelvic adhesions to Doppler ultrasound findings in patients with ovarian endometriomas. METHODS:62 patients who underwent laparoscopic surgery for endometrioma were divided into two groups according to their pelvic pain symptoms. Group 1 (n = 27) included patie...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-012-2630-x

    authors: Seckin B,Oruc AS,Turkcapar F,Ugur M

    更新日期:2013-04-01 00:00:00

  • Cytogenetics of human spermatozoa. The frequency of various chromosome aberrations and their relationship to clinical and biological parameters.

    abstract::Human sperm chromosomes can be visualized after their fusion with zona-free hamster eggs. We analyzed a total of 867 metaphases from 33 men that had been classified into three different groups. We present a detailed summary of the kind and frequency of chromosome aberrations we encountered. A comparison of our results...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:

    authors: Rosenbusch B,Sterzik K

    更新日期:1994-01-01 00:00:00

  • A comparison of misoprostol, controlled-release dinoprostone vaginal insert and oxytocin for cervical ripening.

    abstract:OBJECTIVE:We compared the safety and effectiveness of oxytocin, dinoprostone and misoprostol for cervical priming. STUDY DESIGN:A total of 218 patients were enrolled to receive between one and three treatments according to physicians' options. The end points were: (1) vaginal delivery or Bishop score ≥ 8 at the end of...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-011-1844-7

    authors: Silfeler DB,Tandogan B,Ayvaci H,Silfeler I,Yenidede I,Dayicioglu V

    更新日期:2011-12-01 00:00:00

  • Metabolic changes in follicular fluids of patients treated with recombinant versus urinary human chorionic gonadotropin for triggering ovulation in assisted reproductive technologies: a metabolomics pilot study.

    abstract:INTRODUCTION:The main goal of this retrospective cohort study is the assessment of the effects of administration of recombinant-hCG (r-hCG) versus urinary-hCG (u-hCG) on follicular fluid (FF) composition of women who underwent in vitro fertilization (IVF) treatments. MATERIALS AND METHODS:We selected 70 patients with ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-020-05609-z

    authors: Castiglione Morelli MA,Iuliano A,Schettini SCA,Petruzzi D,Ferri A,Colucci P,Viggiani L,Ostuni A

    更新日期:2020-09-01 00:00:00

  • High-grade serous ovarian cancer: the clone wars.

    abstract:BACKGROUND:The last 5 years' studies using next-generation sequencing provided evidences that many types of solid tumors present spatial and temporal genetic heterogeneity and are composed of multiple populations of genetically distinct subclones that evolve over time following a pattern of branched evolution. The evol...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-017-4292-1

    authors: Salomon-Perzyński A,Salomon-Perzyńska M,Michalski B,Skrzypulec-Plinta V

    更新日期:2017-03-01 00:00:00

  • The individualized significance of lymphadenectomy across all age groups and histologies in malignant ovarian germ cell tumors.

    abstract:PURPOSE:To evaluate the therapeutic role of lymphadenectomy on patients with malignant ovarian germ cell tumor (MOGCT) and to investigate the risk factors of lymph node metastasis. METHODS:Patients of MOGCT between 1988 and 2013 with definite lymph node information were extracted from the Surveillance, Epidemiology, a...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-020-05772-3

    authors: Wang J,Chen R,Li J,Lu X

    更新日期:2020-12-01 00:00:00

  • Sonographic evaluation of kidney parenchymal growth in the fetus.

    abstract:OBJECTIVE:The aim of the study was to establish a nomogram for renal parenchymal thickness throughout pregnancy. METHODS:One-hundred and twenty-eight healthy women with singleton, well-dated, uncomplicated second- or third-trimester pregnancies were prospectively evaluated for renal parenchymal thickness on routine ul...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-012-2376-5

    authors: Hadar E,Davidovits M,Mashiach R,Vardimon D,Bardin R,Efrat Z,Danon D,Roth S,Meizner I

    更新日期:2012-10-01 00:00:00

  • Revisit of risk factors for major obstetric hemorrhage: insights from a large medical center.

    abstract:PURPOSE:To revisit risk factors of major obstetric hemorrhage in a large obstetric center. STUDY DESIGN:A retrospective case control study was conducted based on institutional electronic database and blood bank registry of a single center, 2005-2014. The major obstetric hemorrhage event was defined as transfusion of ≥...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-015-3725-y

    authors: Helman S,Drukker L,Fruchtman H,Ioscovich A,Farkash R,Avitan T,Samueloff A,Grisaru-Granovsky S

    更新日期:2015-10-01 00:00:00

  • Fetal transverse cerebellar diameter measured by ultrasound does not differ between genders.

    abstract:PURPOSE:The aim of this study was to determine the correlation between fetal transverse cerebellar diameter (TCD) and gestational age of male and female fetus in women under low-risk prenatal care between the 13th and 40th week of gestation. METHODS:A cross-sectional study was carried out with 184 pregnant women, at t...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-010-1644-5

    authors: Holanda-Filho JA,Souza AI,Souza AS,Figueroa JN,Ferreira AL,Cabral-Filho JE

    更新日期:2011-08-01 00:00:00

  • Fecundity and morbidity following acute pelvic inflammatory disease treated with doxycycline and metronidazole.

    abstract::We studied fecundity and late sequelae of 39 women who had laparoscopic and microbiological sampling-proven acute pelvic inflammatory disease (PID) treated with the same antimicrobial regimen. The grade and etiology of index PID were classified using laparoscopy, endometrial biopsy and microbiological cultures from th...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-002-0376-6

    authors: Heinonen PK,Leinonen M

    更新日期:2003-10-01 00:00:00

  • Unexpected malignancies after laparoscopic-assisted supracervical hysterectomies (LASH): an analysis of 1,584 LASH cases.

    abstract:OBJECTIVE:The objective of this research was to identify the rate of unexpected malignancies after laparoscopic-assisted supracervical hysterectomies (LASH) and describe the therapy regime. METHODS:The research is based on a retrospective chart analysis of patients undergoing a simple hysterectomy in the gynecological...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-012-2559-0

    authors: Theben JU,Schellong AR,Altgassen C,Kelling K,Schneider S,Große-Drieling D

    更新日期:2013-03-01 00:00:00

  • Congenital diaphragmatic hernia, etiology and management, a 10-year analysis of a single center.

    abstract:OBJECTIVE:To analyze congenital diaphragmatic hernia (CDH) during a 10-year period at the University of Kiel, from 1995 through 2004, in order to develop a strategy to improve prenatal diagnosis, to be able to consider endoscopical treatment for selected cases and to assess the current postnatal treatment strategies. ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-007-0407-4

    authors: Beck C,Alkasi O,Nikischin W,Engler S,Caliebe A,Leuschner I,von Kaisenberg CS

    更新日期:2008-01-01 00:00:00

  • Does tumor grade influence the rate of lymph node metastasis in apparent early stage ovarian cancer?

    abstract:PURPOSE:To evaluate the prevalence of regional lymph node (LN) metastasis in patients with non-clear cell epithelial ovarian cancer apparently confined to the ovary, stratified by tumor grade. METHODS:The National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database was accessed (1988-2014). ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-018-4789-2

    authors: Nasioudis D,Mastroyannis SA,Ko EM,Latif NA

    更新日期:2018-07-01 00:00:00

  • Prolactin and cortisol levels during spontaneous and oxytocin induced labour and the effect of meperidine.

    abstract::The effect of stress during labour on the plasma concentration of prolactin and cortisol was studied in 30 healthy multiparous women. The plasma concentrations of prolactin and cortisol were measured by radioimmunoassay during oxytocin induced labour, spontaneous labour, delivery and postpartum 24 h. The parturients w...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/BF01560086

    authors: Onur E,Erçal T,Karslioğlu I

    更新日期:1989-01-01 00:00:00