Abstract:
:The effective diffusivity of oxygen, D(e), in Ca-alginate and PVA-SbQ gels was measured using a two-chamber vessel with a membrane between the two chambers. The effect of cell density, C(c), on D(e) in Ca-alginate gels was studied. The effective diffusivity of oxygen decreased with increasing cell density, to C(c) = 170 kg dry cells/m(3) gel. The dependency of D(e) on cell density was discussed in terms of a random-pore model. The model correlated well with experimental data, i.e., kD(e)/D(0) = 0.86(1 - 1.47 x 10(-3) C(c))(2). Here, k is the partition coefficient, and D(0) is diffusivity in water.
journal_name
Biotechnol Bioengjournal_title
Biotechnology and bioengineeringauthors
Sun Y,Furusaki S,Yamauchi A,Ichimura Kdoi
10.1002/bit.260340107subject
Has Abstractpub_date
1989-06-05 00:00:00pages
55-8issue
1eissn
0006-3592issn
1097-0290journal_volume
34pub_type
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